Portrait de Yoshua Bengio

Yoshua Bengio

Membre académique principal
Chaire en IA Canada-CIFAR
Professeur titulaire, Université de Montréal, Département d'informatique et de recherche opérationnelle
Fondateur et Conseiller scientifique, Équipe de direction
Sujets de recherche
Apprentissage automatique médical
Apprentissage de représentations
Apprentissage par renforcement
Apprentissage profond
Causalité
Modèles génératifs
Modèles probabilistes
Modélisation moléculaire
Neurosciences computationnelles
Raisonnement
Réseaux de neurones en graphes
Réseaux de neurones récurrents
Théorie de l'apprentissage automatique
Traitement du langage naturel

Biographie

*Pour toute demande média, veuillez écrire à medias@mila.quebec.

Pour plus d’information, contactez Cassidy MacNeil, adjointe principale et responsable des opérations cassidy.macneil@mila.quebec.

Reconnu comme une sommité mondiale en intelligence artificielle, Yoshua Bengio s’est surtout distingué par son rôle de pionnier en apprentissage profond, ce qui lui a valu le prix A. M. Turing 2018, le « prix Nobel de l’informatique », avec Geoffrey Hinton et Yann LeCun. Il est professeur titulaire à l’Université de Montréal, fondateur et conseiller scientifique de Mila – Institut québécois d’intelligence artificielle, et codirige en tant que senior fellow le programme Apprentissage automatique, apprentissage biologique de l'Institut canadien de recherches avancées (CIFAR). Il occupe également la fonction de conseiller spécial et directeur scientifique fondateur d’IVADO.

En 2018, il a été l’informaticien qui a recueilli le plus grand nombre de nouvelles citations au monde. En 2019, il s’est vu décerner le prestigieux prix Killam. Depuis 2022, il détient le plus grand facteur d’impact (h-index) en informatique à l’échelle mondiale. Il est fellow de la Royal Society de Londres et de la Société royale du Canada, et officier de l’Ordre du Canada.

Soucieux des répercussions sociales de l’IA et de l’objectif que l’IA bénéficie à tous, il a contribué activement à la Déclaration de Montréal pour un développement responsable de l’intelligence artificielle.

Étudiants actuels

Collaborateur·rice alumni - McGill
Collaborateur·rice de recherche - Cambridge University
Superviseur⋅e principal⋅e :
Doctorat - UdeM
Collaborateur·rice de recherche - N/A
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Doctorat - UdeM
Collaborateur·rice de recherche - KAIST
Collaborateur·rice alumni - UdeM
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Visiteur de recherche indépendant
Superviseur⋅e principal⋅e :
Doctorat - UdeM
Co-superviseur⋅e :
Doctorat - UdeM
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice alumni - UdeM
Postdoctorat - UdeM
Superviseur⋅e principal⋅e :
Postdoctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice alumni
Collaborateur·rice alumni - UdeM
Doctorat - UdeM
Co-superviseur⋅e :
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Visiteur de recherche indépendant - UdeM
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice de recherche - Ying Wu Coll of Computing
Collaborateur·rice de recherche - University of Waterloo
Superviseur⋅e principal⋅e :
Collaborateur·rice alumni - Max-Planck-Institute for Intelligent Systems
Doctorat - UdeM
Postdoctorat - UdeM
Postdoctorat - UdeM
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice alumni - UdeM
Postdoctorat
Co-superviseur⋅e :
Collaborateur·rice alumni - Polytechnique
Co-superviseur⋅e :
Doctorat - UdeM
Co-superviseur⋅e :
Collaborateur·rice de recherche
Superviseur⋅e principal⋅e :
Collaborateur·rice alumni - UdeM
Collaborateur·rice alumni - UdeM
Co-superviseur⋅e :
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice de recherche
Collaborateur·rice de recherche - UdeM
Doctorat - McGill
Superviseur⋅e principal⋅e :
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice alumni - McGill
Superviseur⋅e principal⋅e :

Publications

GraphMix: Improved Training of GNNs for Semi-Supervised Learning
We present GraphMix, a regularization method for Graph Neural Network based semi-supervised object classification, whereby we propose to tra… (voir plus)in a fully-connected network jointly with the graph neural network via parameter sharing and interpolation-based regularization. Further, we provide a theoretical analysis of how GraphMix improves the generalization bounds of the underlying graph neural network, without making any assumptions about the "aggregation" layer or the depth of the graph neural networks. We experimentally validate this analysis by applying GraphMix to various architectures such as Graph Convolutional Networks, Graph Attention Networks and Graph-U-Net. Despite its simplicity, we demonstrate that GraphMix can consistently improve or closely match state-of-the-art performance using even simpler architectures such as Graph Convolutional Networks, across three established graph benchmarks: Cora, Citeseer and Pubmed citation network datasets, as well as three newly proposed datasets: Cora-Full, Co-author-CS and Co-author-Physics.
COVI-AgentSim: an Agent-based Model for Evaluating Methods of Digital Contact Tracing
Prateek Gupta
Nasim Rahaman
Hannah Alsdurf
Abhinav Sharma
Nanor Minoyan
Soren Harnois Leblanc
Pierre-Luc St. Charles
Akshay Patel
Joumana Ghosn
Yang Zhang
Bernhard Schölkopf
Christopher Pal
Joanna Merckx
The rapid global spread of COVID-19 has led to an unprecedented demand for effective methods to mitigate the spread of the disease, and vari… (voir plus)ous digital contact tracing (DCT) methods have emerged as a component of the solution. In order to make informed public health choices, there is a need for tools which allow evaluation and comparison of DCT methods. We introduce an agent-based compartmental simulator we call COVI-AgentSim, integrating detailed consideration of virology, disease progression, social contact networks, and mobility patterns, based on parameters derived from empirical research. We verify by comparing to real data that COVI-AgentSim is able to reproduce realistic COVID-19 spread dynamics, and perform a sensitivity analysis to verify that the relative performance of contact tracing methods are consistent across a range of settings. We use COVI-AgentSim to perform cost-benefit analyses comparing no DCT to: 1) standard binary contact tracing (BCT) that assigns binary recommendations based on binary test results; and 2) a rule-based method for feature-based contact tracing (FCT) that assigns a graded level of recommendation based on diverse individual features. We find all DCT methods consistently reduce the spread of the disease, and that the advantage of FCT over BCT is maintained over a wide range of adoption rates. Feature-based methods of contact tracing avert more disability-adjusted life years (DALYs) per socioeconomic cost (measured by productive hours lost). Our results suggest any DCT method can help save lives, support re-opening of economies, and prevent second-wave outbreaks, and that FCT methods are a promising direction for enriching BCT using self-reported symptoms, yielding earlier warning signals and a significantly reduced spread of the virus per socioeconomic cost.
Generating Multiscale Amorphous Molecular Structures Using Deep Learning: A Study in 2D.
Michael Kilgour
Nicolas Gastellu
David Y. T. Hui
Amorphous molecular assemblies appear in a vast array of systems: from living cells to chemical plants and from everyday items to new device… (voir plus)s. The absence of long-range order in amorphous materials implies that precise knowledge of their underlying structures throughout is needed to rationalize and control their properties at the mesoscale. Standard computational simulations suffer from exponentially unfavorable scaling of the required compute with system size. We present a method based on deep learning that leverages the finite range of structural correlations for an autoregressive generation of disordered molecular aggregates up to arbitrary size from small-scale computational or experimental samples. We benchmark performance on self-assembled nanoparticle aggregates and proceed to simulate monolayer amorphous carbon with atomistic resolution. This method bridges the gap between the nanoscale and mesoscale simulations of amorphous molecular systems.
A learning-based algorithm to quickly compute good primal solutions for Stochastic Integer Programs
Andrea Lodi
Sriram Sankaranarayanan
We propose a novel approach using supervised learning to obtain near-optimal primal solutions for two-stage stochastic integer programming (… (voir plus)2SIP) problems with constraints in the first and second stages. The goal of the algorithm is to predict a "representative scenario" (RS) for the problem such that, deterministically solving the 2SIP with the random realization equal to the RS, gives a near-optimal solution to the original 2SIP. Predicting an RS, instead of directly predicting a solution ensures first-stage feasibility of the solution. If the problem is known to have complete recourse, second-stage feasibility is also guaranteed. For computational testing, we learn to find an RS for a two-stage stochastic facility location problem with integer variables and linear constraints in both stages and consistently provide near-optimal solutions. Our computing times are very competitive with those of general-purpose integer programming solvers to achieve a similar solution quality.
Mastering Rate based Curriculum Learning
Deriving Differential Target Propagation from Iterating Approximate Inverses
Predicting COVID-19 Pneumonia Severity on Chest X-ray With Deep Learning
Beiyi Shen
Almas F Abbasi
Hoshmand Kochi Mahsa
Marzyeh Ghassemi
Haifang Li
Tim Q Duong
Introduction The need to streamline patient management for coronavirus disease-19 (COVID-19) has become more pressing than ever. Chest X-ray… (voir plus)s (CXRs) provide a non-invasive (potentially bedside) tool to monitor the progression of the disease. In this study, we present a severity score prediction model for COVID-19 pneumonia for frontal chest X-ray images. Such a tool can gauge the severity of COVID-19 lung infections (and pneumonia in general) that can be used for escalation or de-escalation of care as well as monitoring treatment efficacy, especially in the ICU. Methods Images from a public COVID-19 database were scored retrospectively by three blinded experts in terms of the extent of lung involvement as well as the degree of opacity. A neural network model that was pre-trained on large (non-COVID-19) chest X-ray datasets is used to construct features for COVID-19 images which are predictive for our task. Results This study finds that training a regression model on a subset of the outputs from this pre-trained chest X-ray model predicts our geographic extent score (range 0-8) with 1.14 mean absolute error (MAE) and our lung opacity score (range 0-6) with 0.78 MAE. Conclusions These results indicate that our model’s ability to gauge the severity of COVID-19 lung infections could be used for escalation or de-escalation of care as well as monitoring treatment efficacy, especially in the ICU. To enable follow up work, we make our code, labels, and data available online.
Learning to Navigate the Synthetically Accessible Chemical Space Using Reinforcement Learning
Sai Krishna Gottipati
Boris Sattarov
Sufeng Niu
Yashaswi Pathak
Haoran Wei
Karam J. Thomas
Connor W. Coley
Over the last decade, there has been significant progress in the field of machine learning for de novo drug design, particularly in deep gen… (voir plus)erative models. However, current generative approaches exhibit a significant challenge as they do not ensure that the proposed molecular structures can be feasibly synthesized nor do they provide the synthesis routes of the proposed small molecules, thereby seriously limiting their practical applicability. In this work, we propose a novel forward synthesis framework powered by reinforcement learning (RL) for de novo drug design, Policy Gradient for Forward Synthesis (PGFS), that addresses this challenge by embedding the concept of synthetic accessibility directly into the de novo drug design system. In this setup, the agent learns to navigate through the immense synthetically accessible chemical space by subjecting commercially available small molecule building blocks to valid chemical reactions at every time step of the iterative virtual multi-step synthesis process. The proposed environment for drug discovery provides a highly challenging test-bed for RL algorithms owing to the large state space and high-dimensional continuous action space with hierarchical actions. PGFS achieves state-of-the-art performance in generating structures with high QED and penalized clogP. Moreover, we validate PGFS in an in-silico proof-of-concept associated with three HIV targets. Finally, we describe how the end-to-end training conceptualized in this study represents an important paradigm in radically expanding the synthesizable chemical space and automating the drug discovery process.
S2RMs: Spatially Structured Recurrent Modules
Nasim Rahaman
Muhammad Waleed Gondal
Manuel Wuthrich
Stefan Bauer
Y. Sharma
Bernhard Schölkopf
Compositional Generalization by Factorizing Alignment and Translation
Jacob Russin
R. O’Reilly
Exploiting Syntactic Structure for Better Language Modeling: A Syntactic Distance Approach
Wenyu Du
Timothy J. O’Donnell
Yue Zhang
It is commonly believed that knowledge of syntactic structure should improve language modeling. However, effectively and computationally eff… (voir plus)iciently incorporating syntactic structure into neural language models has been a challenging topic. In this paper, we make use of a multi-task objective, i.e., the models simultaneously predict words as well as ground truth parse trees in a form called "syntactic distances", where information between these two separate objectives shares the same intermediate representation. Experimental results on the Penn Treebank and Chinese Treebank datasets show that when ground truth parse trees are provided as additional training signals, the model is able to achieve lower perplexity and induce trees with better quality.
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition
The recent development of sequencing technologies revolutionized our understanding of the inner workings of the cell as well as the way dise… (voir plus)ase is treated. A single RNA sequencing (RNA-Seq) experiment, however, measures tens of thousands of parameters simultaneously. While the results are information rich, data analysis provides a challenge. Dimensionality reduction methods help with this task by extracting patterns from the data by compressing it into compact vector representations. We present the factorized embeddings (FE) model, a self-supervised deep learning algorithm that learns simultaneously, by tensor factorization, gene and sample representation spaces. We ran the model on RNA-Seq data from two large-scale cohorts and observed that the sample representation captures information on single gene and global gene expression patterns. Moreover, we found that the gene representation space was organized such that tissue-specific genes, highly correlated genes as well as genes participating in the same GO terms were grouped. Finally, we compared the vector representation of samples learned by the FE model to other similar models on 49 regression tasks. We report that the representations trained with FE rank first or second in all of the tasks, surpassing, sometimes by a considerable margin, other representations. A toy example in the form of a Jupyter Notebook as well as the code and trained embeddings for this project can be found at: https://github.com/TrofimovAssya/FactorizedEmbeddings. Supplementary data are available at Bioinformatics online.