Yoshua Bengio

Biographie

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Pour plus d’information, contactez Marie-Josée Beauchamp, adjointe administrative à marie-josee.beauchamp@mila.quebec.

Reconnu comme une sommité mondiale en intelligence artificielle, Yoshua Bengio s’est surtout distingué par son rôle de pionnier en apprentissage profond, ce qui lui a valu le prix A. M. Turing 2018, le « prix Nobel de l’informatique », avec Geoffrey Hinton et Yann LeCun. Il est professeur titulaire à l’Université de Montréal, fondateur et conseiller scientifique de Mila – Institut québécois d’intelligence artificielle, et codirige en tant que senior fellow le programme Apprentissage automatique, apprentissage biologique de l'Institut canadien de recherches avancées (CIFAR). Il occupe également la fonction de conseiller spécial et directeur scientifique fondateur d’IVADO.

En 2018, il a été l’informaticien qui a recueilli le plus grand nombre de nouvelles citations au monde. En 2019, il s’est vu décerner le prestigieux prix Killam. Depuis 2022, il détient le plus grand facteur d’impact (h-index) en informatique à l’échelle mondiale. Il est fellow de la Royal Society de Londres et de la Société royale du Canada, et officier de l’Ordre du Canada.

Soucieux des répercussions sociales de l’IA et de l’objectif que l’IA bénéficie à tous, il a contribué activement à la Déclaration de Montréal pour un développement responsable de l’intelligence artificielle.

Étudiants actuels

Jamal Abou Haibeh

Collaborateur·rice alumni - McGill

Mohammed Abukalam

Collaborateur·rice alumni - UdeM

agassoussisalwane2@gmail.com

Salwane Agassoussi

UdeM

Berkes Anaïs

Collaborateur·rice de recherche - Cambridge University

Superviseur⋅e principal⋅e :

Rim Assouel

Doctorat - UdeM

Ayoub Atanane

Collaborateur·rice alumni - Université du Québec à Rimouski

Stefan Bauer

Visiteur de recherche indépendant

Co-superviseur⋅e :

Guillaume Lajoie

Paul Bertin

Doctorat - UdeM

Ghait Boukachab

Collaborateur·rice alumni - UQAR

Shahana Chatterjee

Collaborateur·rice de recherche - N/A

Superviseur⋅e principal⋅e :

Doctorat - UdeM

Collaborateur·rice de recherche - KAIST

Doctorat - UdeM

Doctorat - UdeM

Collaborateur·rice alumni - UdeM

Eric Elmoznino

Doctorat - UdeM

Co-superviseur⋅e :

Doctorat - UdeM

Doctorat - UdeM

Doctorat - UdeM

Co-superviseur⋅e :

Leo Feng

Doctorat - UdeM

Stagiaire de recherche - UdeM

Ivan Grega

Stagiaire de recherche - UdeM

Pietro Greiner

Doctorat

Mohsin Hasan

Doctorat - UdeM

mohsin.hasan@mila.quebec

Edward Hu

Doctorat - UdeM

Moksh Jain

Doctorat - UdeM

moksh.jain@mila.quebec

Maîtrise recherche - UdeM

Co-superviseur⋅e :

Collaborateur·rice alumni - UdeM

Hyeonah Kim

Postdoctorat - UdeM

Superviseur⋅e principal⋅e :

Alex Hernandez

Minsu Kim

Stagiaire de recherche - UdeM

Collaborateur·rice de recherche - UdeM

Michał Koziarski

Collaborateur·rice alumni - UdeM

Salem Lahlou

Collaborateur·rice alumni - UdeM

Tabitha Edith Lee

Postdoctorat - UdeM

Superviseur⋅e principal⋅e :

Seanie Lee

Collaborateur·rice alumni - UdeM

Collaborateur·rice alumni

Zhen Liu

Collaborateur·rice alumni - UdeM

Superviseur⋅e principal⋅e :

Liam Paull

Kanika Madan

Doctorat - UdeM

Mohammed Mahfoud

Collaborateur·rice alumni - UdeM

Nikolay Malkin

Collaborateur·rice alumni - UdeM

Cristian Dragos Manta

Doctorat - UdeM

Co-superviseur⋅e :

Dhanya Sridhar

Sören Mindermann

Collaborateur·rice de recherche - UdeM

Sarthak Mittal

Doctorat - UdeM

Superviseur⋅e principal⋅e :

Doctorat - UdeM

Superviseur⋅e principal⋅e :

Postdoctorat - UdeM

Superviseur⋅e principal⋅e :

Visiteur de recherche indépendant - UdeM

Padideh Nouri

Doctorat - UdeM

Superviseur⋅e principal⋅e :

Ali Parviz

Collaborateur·rice de recherche - Ying Wu Coll of Computing

Lena Podina

Doctorat - University of Waterloo

Superviseur⋅e principal⋅e :

David Rolnick

Camille Rochefort-Boulanger

Nassim Rahaman

Collaborateur·rice alumni - Max-Planck-Institute for Intelligent Systems

Doctorat - UdeM

Postdoctorat - UdeM

Visiteur de recherche indépendant - UdeM

Postdoctorat - UdeM

Doctorat - UdeM

Superviseur⋅e principal⋅e :

Julie Hussin

Victor Schmidt

Collaborateur·rice alumni - UdeM

Postdoctorat - UdeM

Maîtrise recherche - UdeM

Marcin Sendera

Collaborateur·rice alumni - UdeM

Vedant Shah

Maîtrise recherche - UdeM

Postdoctorat

Marco Stock

Visiteur de recherche indépendant - Technical University of Munich

marco.stock@tum.de

Mélisande Astrid Crystal Teng

Doctorat - UdeM

Co-superviseur⋅e :

Collaborateur·rice de recherche - RWTH Aachen University (Rheinisch-Westfälische Technische Hochschule Aachen)

Superviseur⋅e principal⋅e :

David Rolnick

alexander.tong@mila.quebec

Alex Tong

Postdoctorat - UdeM

Postdoctorat - UdeM

Co-superviseur⋅e :

Doctorat - UdeM

Superviseur⋅e principal⋅e :

Collaborateur·rice de recherche - UdeM

Zichao Yan

Collaborateur·rice alumni - UdeM

Omar G. Younis

Collaborateur·rice de recherche

Collaborateur·rice de recherche - KAIST

Skipper : combiner l’abstraction spatiale et temporelle afin d’améliorer la généralisation

Nicole Zhang

Doctorat - McGill

Superviseur⋅e principal⋅e :

Doctorat - UdeM

Superviseur⋅e principal⋅e :

Doctorat - UdeM

Harry Zhao

Doctorat - McGill

Superviseur⋅e principal⋅e :

Billets de blogue

Generic thumbnail for Mila Blog articles.

22 février 2024

par

Mingde Harry Zhao

Safa Alver

Harm van Seijen

Romain Laroche

Doina Precup

Yoshua Bengio

Mise à l’échelle au service du raisonnement et de l’apprentissage automatique basé sur un modèle

Scaling in the service of reasoning & model-based ML

4 avril 2023

par

Yoshua Bengio

Edward J. Hu

Une collaboration entre Mila et Relation Therapeutics pour découvrir in vitro de nouvelles associations médicamenteuses synergiques

A collaboration between Mila and Relation Therapeutics to discover novel synergistic combinations of drugs in vitro

23 mars 2022

par

Paul Bertin

Jake P. Taylor-King

Yoshua Bengio

Les réseaux de flot génératifs

15 mars 2022

par

Yoshua Bengio

Publications

Trajectory Flow Matching with Applications to Clinical Time Series Modelling

Xi Zhang

Yuan Pu

Yuki Kawamura

Andrew Loza

Dennis Shung

Alexander Tong

Modeling stochastic and irregularly sampled time series is a challenging problem found in a wide range of applications, especially in medici… (voir plus)ne. Neural stochastic differential equations (Neural SDEs) are an attractive modeling technique for this problem, which parameterize the drift and diffusion terms of an SDE with neural networks. However, current algorithms for training Neural SDEs require backpropagation through the SDE dynamics, greatly limiting their scalability and stability. To address this, we propose **Trajectory Flow Matching** (TFM), which trains a Neural SDE in a *simulation-free* manner, bypassing backpropagation through the dynamics. TFM leverages the flow matching technique from generative modeling to model time series. In this work we first establish necessary conditions for TFM to learn time series data. Next, we present a reparameterization trick which improves training stability. Finally, we adapt TFM to the clinical time series setting, demonstrating improved performance on three clinical time series datasets both in terms of absolute performance and uncertainty prediction.

2024-09-25

NeurIPS.cc/2024/Conference (spotlight)

openreview.net

A neuronal least-action principle for real-time learning in cortical circuits

Walter Senn

Dominik Dold

Akos F. Kungl

Benjamin Ellenberger

Jakob Jordan

João Sacramento

Mihai A. Petrovici

One of the most fundamental laws of physics is the principle of least action. Motivated by its predictive power, we introduce a neuronal lea… (voir plus)st-action principle for cortical processing of sensory streams to produce appropriate behavioural outputs in real time. The principle postulates that the voltage dynamics of cortical pyramidal neurons prospectively minimizes the local somato-dendritic mismatch error within individual neurons. For output neurons, the principle implies minimizing an instantaneous behavioural error. For deep network neurons, it implies the prospective firing to overcome integration delays and correct for possible output errors right in time. The neuron-specific errors are extracted in the apical dendrites of pyramidal neurons through a cortical microcircuit that tries to explain away the feedback from the periphery, and correct the trajectory on the fly. Any motor output is in a moving equilibrium with the sensory input and the motor feedback during the ongoing sensory-motor transform. Online synaptic plasticity reduces the somato-dendritic mismatch error within each cortical neuron and performs gradient descent on the output cost at any moment in time. The neuronal least-action principle offers an axiomatic framework to derive local neuronal and synaptic laws for global real-time computation and learning in the brain.

2024-09-23

bioRxiv (prépublication)

A neuronal least-action principle for real-time learning in cortical circuits

Walter Senn

Dominik Dold

Akos F. Kungl

Benjamin Ellenberger

Jakob Jordan

João Sacramento

Mihai A. Petrovici

2024-09-23

bioRxiv (prépublication)

AI content detection in the emerging information ecosystem: new obligations for media and tech companies

Alistair Knott

Dino Pedreschi

Toshiya Jitsuzumi

Susan Leavy

D. Eyers

Tapabrata Chakraborti

Andrew Trotman

Sundar Sundareswaran

Ricardo Baeza-Yates

Przemyslaw Biecek

Adrian Weller

Paul D. Teal

Subhadip Basu

Mehmet Haklidir

Virginia Morini

Stuart Russell

2024-09-21

Ethics and Information Technology (publié)

A high-throughput phenotypic screen combined with an ultra-large-scale deep learning-based virtual screening reveals novel scaffolds of antibacterial compounds

Gabriele Scalia

Steven T. Rutherford

Ziqing Lu

Kerry R. Buchholz

Nicholas Skelton

Kangway Chuang

Nathaniel Diamant

Jan-Christian Hütter

Jerome-Maxim Luescher

Anh Miu

Jeff Blaney

Leo Gendelev

Elizabeth Skippington

Greg Zynda

Nia Dickson

Michał Koziarski

Aviv Regev

Man-Wah Tan

Tommasso Biancalani

The proliferation of multi-drug-resistant bacteria underscores an urgent need for novel antibiotics. Traditional discovery methods face chal… (voir plus)lenges due to limited chemical diversity, high costs, and difficulties in identifying structurally novel compounds. Here, we explore the integration of small molecule high-throughput screening with a deep learning-based virtual screening approach to uncover new antibacterial compounds. Leveraging a diverse library of nearly 2 million small molecules, we conducted comprehensive phenotypic screening against a sensitized Escherichia coli strain that, at a low hit rate, yielded thousands of hits. We trained a deep learning model, GNEprop, to predict antibacterial activity, ensuring robustness through out-of-distribution generalization techniques. Virtual screening of over 1.4 billion compounds identified potential candidates, of which 82 exhibited antibacterial activity, illustrating a 90X improved hit rate over the high-throughput screening experiment GNEprop was trained on. Importantly, a significant portion of these newly identified compounds exhibited high dissimilarity to known antibiotics, indicating promising avenues for further exploration in antibiotic discovery.

2024-09-14

bioRxiv (prépublication)

A high-throughput phenotypic screen combined with an ultra-large-scale deep learning-based virtual screening reveals novel scaffolds of antibacterial compounds

Gabriele Scalia

Steven T. Rutherford

Ziqing Lu

Kerry R. Buchholz

Nicholas Skelton

Kangway Chuang

Nathaniel Diamant

Jan-Christian Hütter

Jerome-Maxim Luescher

Anh Miu

Jeff Blaney

Leo Gendelev

Elizabeth Skippington

Greg Zynda

Nia Dickson

Michał Koziarski

Aviv Regev

Man-Wah Tan

Tommaso Biancalani

2024-09-14

bioRxiv (prépublication)

Foundational Challenges in Assuring Alignment and Safety of Large Language Models

Usman Anwar

Abulhair Saparov

Javier Rando

Daniel Paleka

Miles Turpin

Peter Hase

Ekdeep Singh Lubana

Erik Jenner

Stephen Casper

Oliver Sourbut

Benjamin L. Edelman

Zhaowei Zhang

Mario Günther

Anton Korinek

Jose Hernandez-Orallo

Lewis Hammond

Eric J Bigelow

Alexander Pan

Lauro Langosco

Tomasz Korbak … (voir 22 de plus)

Heidi Chenyu Zhang

Ruiqi Zhong

Sean O hEigeartaigh

Gabriel Recchia

Giulio Corsi

Alan Chan

Markus Anderljung

Lilian Edwards

Aleksandar Petrov

Christian Schroeder de Witt

Danqi Chen

Samuel Albanie

Sumeet Ramesh Motwani

Tegan Maharaj

Jakob Nicolaus Foerster

Philip Torr

Florian Tramèr

He He

Atoosa Kasirzadeh

Yejin Choi

David Scott Krueger

2024-09-02

TMLR (accepté)

openreview.net

Zero-Shot Object-Centric Representation Learning

Aniket Rajiv Didolkar

Andrii Zadaianchuk

Anirudh Goyal

Michael Curtis Mozer

Georg Martius

Maximilian Seitzer

The goal of object-centric representation learning is to decompose visual scenes into a structured representation that isolates the entities… (voir plus). Recent successes have shown that object-centric representation learning can be scaled to real-world scenes by utilizing pre-trained self-supervised features. However, so far, object-centric methods have mostly been applied in-distribution, with models trained and evaluated on the same dataset. This is in contrast to the wider trend in machine learning towards general-purpose models directly applicable to unseen data and tasks. Thus, in this work, we study current object-centric methods through the lens of zero-shot generalization by introducing a benchmark comprising eight different synthetic and real-world datasets. We analyze the factors influencing zero-shot performance and find that training on diverse real-world images improves transferability to unseen scenarios. Furthermore, inspired by the success of task-specific fine-tuning in foundation models, we introduce a novel fine-tuning strategy to adapt pre-trained vision encoders for the task of object discovery. We find that the proposed approach results in state-of-the-art performance for unsupervised object discovery, exhibiting strong zero-shot transfer to unseen datasets.

2024-08-17

ArXiv (prépublication)

Zero-Shot Object-Centric Representation Learning

Aniket Rajiv Didolkar

Andrii Zadaianchuk

Anirudh Goyal

Michael Curtis Mozer

Georg Martius

Maximilian Seitzer

2024-08-17

ArXiv (prépublication)

Zero-Shot Object-Centric Representation Learning

Aniket Rajiv Didolkar

Andrii Zadaianchuk

Anirudh Goyal

Michael Curtis Mozer

Georg Martius

Maximilian Seitzer

2024-08-17

ArXiv (prépublication)

Can a Bayesian Oracle Prevent Harm from an Agent?

Michael K. Cohen

Nikolay Malkin

Matt MacDermott

Damiano Fornasiere

Pietro Greiner

Younesse Kaddar

Is there a way to design powerful AI systems based on machine learning methods that would satisfy probabilistic safety guarantees? With the … (voir plus)long-term goal of obtaining a probabilistic guarantee that would apply in every context, we consider estimating a context-dependent bound on the probability of violating a given safety specification. Such a risk evaluation would need to be performed at run-time to provide a guardrail against dangerous actions of an AI. Noting that different plausible hypotheses about the world could produce very different outcomes, and because we do not know which one is right, we derive bounds on the safety violation probability predicted under the true but unknown hypothesis. Such bounds could be used to reject potentially dangerous actions. Our main results involve searching for cautious but plausible hypotheses, obtained by a maximization that involves Bayesian posteriors over hypotheses. We consider two forms of this result, in the iid case and in the non-iid case, and conclude with open problems towards turning such theoretical results into practical AI guardrails.

2024-08-09

ArXiv (prépublication)

openreview.net

Cell Morphology-Guided Small Molecule Generation with GFlowNets

Stephen Zhewen Lu

Ziqing Lu

Ehsan Hajiramezanali

Tommaso Biancalani

Gabriele Scalia

Michał Koziarski

High-content phenotypic screening, including high-content imaging (HCI), has gained popularity in the last few years for its ability to char… (voir plus)acterize novel therapeutics without prior knowledge of the protein target. When combined with deep learning techniques to predict and represent molecular-phenotype interactions, these advancements hold the potential to significantly accelerate and enhance drug discovery applications. This work focuses on the novel task of HCI-guided molecular design. Generative models for molecule design could be guided by HCI data, for example with a supervised model that links molecules to phenotypes of interest as a reward function. However, limited labeled data, combined with the high-dimensional readouts, can make training these methods challenging and impractical. We consider an alternative approach in which we leverage an unsupervised multimodal joint embedding to define a latent similarity as a reward for GFlowNets. The proposed model learns to generate new molecules that could produce phenotypic effects similar to those of the given image target, without relying on pre-annotated phenotypic labels. We demonstrate that the proposed method generates molecules with high morphological and structural similarity to the target, increasing the likelihood of similar biological activity, as confirmed by an independent oracle model.

2024-08-09

ArXiv (prépublication)