Portrait de Guy Wolf

Guy Wolf

Membre académique principal
Chaire en IA Canada-CIFAR
Professeur agrégé, Université de Montréal, Département de mathématiques et statistiques
Concordia University
CHUM - Montreal University Hospital Center
Sujets de recherche
Apprentissage automatique médical
Apprentissage de représentations
Apprentissage multimodal
Apprentissage profond
Apprentissage spectral
Apprentissage sur graphes
Exploration des données
Modélisation moléculaire
Recherche d'information
Réseaux de neurones en graphes
Systèmes dynamiques
Théorie de l'apprentissage automatique

Biographie

Guy Wolf est professeur agrégé au Département de mathématiques et de statistique de l'Université de Montréal. Ses intérêts de recherche se situent au carrefour de l'apprentissage automatique, de la science des données et des mathématiques appliquées. Il s'intéresse particulièrement aux méthodes d'exploration de données qui utilisent l'apprentissage multiple et l'apprentissage géométrique profond, ainsi qu'aux applications pour l'analyse exploratoire des données biomédicales.

Ses recherches portent sur l'analyse exploratoire des données, avec des applications en bio-informatique. Ses approches sont multidisciplinaires et combinent l'apprentissage automatique, le traitement du signal et les outils mathématiques appliqués. En particulier, ses travaux récents utilisent une combinaison de géométries de diffusion et d'apprentissage profond pour trouver des modèles émergents, des dynamiques et des structures dans les mégadonnées à grande dimension (par exemple, dans la génomique et la protéomique de la cellule unique).

Étudiants actuels

Maîtrise recherche - UdeM
Co-superviseur⋅e :
Doctorat - UdeM
Collaborateur·rice alumni
Collaborateur·rice alumni - UdeM
Collaborateur·rice de recherche - Western Washington University (faculty; assistant prof))
Co-superviseur⋅e :
Collaborateur·rice alumni - McGill
Maîtrise recherche - Concordia
Superviseur⋅e principal⋅e :
Doctorat - Concordia
Superviseur⋅e principal⋅e :
Maîtrise recherche - UdeM
Superviseur⋅e principal⋅e :
Stagiaire de recherche - UdeM
Postdoctorat - UdeM
Doctorat - UdeM
Doctorat - UdeM
Co-superviseur⋅e :
Maîtrise recherche - Concordia
Superviseur⋅e principal⋅e :
Doctorat - UdeM
Doctorat - UdeM
Co-superviseur⋅e :
Postdoctorat - Concordia
Superviseur⋅e principal⋅e :
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Doctorat - UdeM
Doctorat - Concordia
Superviseur⋅e principal⋅e :
Maîtrise recherche - UdeM
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Collaborateur·rice de recherche - UdeM
Co-superviseur⋅e :
Stagiaire de recherche - Western Washington University
Superviseur⋅e principal⋅e :
Postdoctorat - UdeM
Collaborateur·rice de recherche - McGill (assistant professor)

Publications

Channel Selection for Test-Time Adaptation Under Distribution Shift
Pedro Vianna
Muawiz Sajjad Chaudhary
An Tang
Guy Cloutier
Michael Eickenberg
To ensure robustness and generalization to real-world scenarios, test-time adaptation has been recently studied as an approach to adjust mod… (voir plus)els to a new data distribution during inference. Test-time batch normalization is a simple and popular method that achieved compelling performance on domain shift benchmarks by recalculating batch normalization statistics on test batches. However, in many practical applications this technique is vulnerable to label distribution shifts. We propose to tackle this challenge by only selectively adapting channels in a deep network, minimizing drastic adaptation that is sensitive to label shifts. We find that adapted models significantly improve the performance compared to the baseline models and counteract unknown label shifts.
Understanding Graph Neural Networks with Generalized Geometric Scattering Transforms
Michael Perlmutter
Alexander Tong
Feng Gao
Matthew Hirn
The scattering transform is a multilayered wavelet-based deep learning architecture that acts as a model of convolutional neural networks. R… (voir plus)ecently, several works have introduced generalizations of the scattering transform for non-Euclidean settings such as graphs. Our work builds upon these constructions by introducing windowed and non-windowed geometric scattering transforms for graphs based upon a very general class of asymmetric wavelets. We show that these asymmetric graph scattering transforms have many of the same theoretical guarantees as their symmetric counterparts. As a result, the proposed construction unifies and extends known theoretical results for many of the existing graph scattering architectures. In doing so, this work helps bridge the gap between geometric scattering and other graph neural networks by introducing a large family of networks with provable stability and invariance guarantees. These results lay the groundwork for future deep learning architectures for graph-structured data that have learned filters and also provably have desirable theoretical properties.
Comparison of Radiologists and Deep Learning for US Grading of Hepatic Steatosis.
Pedro Vianna
Sara-Ivana Calce
Pamela Boustros
Cassandra Larocque-Rigney
Laurent Patry-Beaudoin
Yi Hui Luo
Emre Aslan
John Marinos
Talal M. Alamri
Kim-Nhien Vu
Jessica Murphy-Lavallée
Jean-Sébastien Billiard
Emmanuel Montagnon
Hongliang Li
Samuel Kadoury
Bich Nguyen
Shanel Gauthier
Benjamin Thérien
Michael Chassé
Guy Cloutier
An Tang
Background Screening for nonalcoholic fatty liver disease (NAFLD) is suboptimal due to the subjective interpretation of US images. Purpose T… (voir plus)o evaluate the agreement and diagnostic performance of radiologists and a deep learning model in grading hepatic steatosis in NAFLD at US, with biopsy as the reference standard. Materials and Methods This retrospective study included patients with NAFLD and control patients without hepatic steatosis who underwent abdominal US and contemporaneous liver biopsy from September 2010 to October 2019. Six readers visually graded steatosis on US images twice, 2 weeks apart. Reader agreement was assessed with use of κ statistics. Three deep learning techniques applied to B-mode US images were used to classify dichotomized steatosis grades. Classification performance of human radiologists and the deep learning model for dichotomized steatosis grades (S0, S1, S2, and S3) was assessed with area under the receiver operating characteristic curve (AUC) on a separate test set. Results The study included 199 patients (mean age, 53 years ± 13 [SD]; 101 men). On the test set (n = 52), radiologists had fair interreader agreement (0.34 [95% CI: 0.31, 0.37]) for classifying steatosis grades S0 versus S1 or higher, while AUCs were between 0.49 and 0.84 for radiologists and 0.85 (95% CI: 0.83, 0.87) for the deep learning model. For S0 or S1 versus S2 or S3, radiologists had fair interreader agreement (0.30 [95% CI: 0.27, 0.33]), while AUCs were between 0.57 and 0.76 for radiologists and 0.73 (95% CI: 0.71, 0.75) for the deep learning model. For S2 or lower versus S3, radiologists had fair interreader agreement (0.37 [95% CI: 0.33, 0.40]), while AUCs were between 0.52 and 0.81 for radiologists and 0.67 (95% CI: 0.64, 0.69) for the deep learning model. Conclusion Deep learning approaches applied to B-mode US images provided comparable performance with human readers for detection and grading of hepatic steatosis. Published under a CC BY 4.0 license. Supplemental material is available for this article. See also the editorial by Tuthill in this issue.
F66. FROM GENE TO COGNITION: MAPPING THE EFFECTS OF GENOMIC DELETIONS AND DUPLICATIONS ON COGNITIVE ABILITY
Sayeh Kazem
Kuldeep Kumar
Guillaume Huguet
Myriam Lizotte
Thomas Renne
Jakub Kopal
Stefan Horoi
Martineau Jean-Louis
Zohra Saci
Laura Almasy
David C. Glahn
Sébastien Jacquemont
Graph topological property recovery with heat and wave dynamics-based features on graphs
Dhananjay Bhaskar
Yanlei Zhang
Charles Xu
Xingzhi Sun
Oluwadamilola Fasina
Maximilian Nickel
Michael Perlmutter
Automated liver segmentation and steatosis grading using deep learning on B-mode ultrasound images
Pedro Vianna
Merve Kulbay
Pamela Boustros
Sara-Ivana Calce
Cassandra Larocque-Rigney
Laurent Patry-Beaudoin
Yi Hui Luo
Muawiz Chaudary
Samuel Kadoury
Bich Nguyen
Emmanuel Montagnon
Michael Chassé
An Tang
Guy Cloutier
Early detection of nonalcoholic fatty liver disease (NAFLD) is crucial to avoid further complications. Ultrasound is often used for screenin… (voir plus)g and monitoring of hepatic steatosis, however it is limited by the subjective interpretation of images. Computer assisted diagnosis could aid radiologists to achieve objective grading, and artificial intelligence approaches have been tested across various medical applications. In this study, we evaluated the performance of a two-stage hepatic steatosis detection deep learning framework, with a first step of liver segmentation and a subsequent step of hepatic steatosis classification. We evaluated the models on internal and external datasets, aiming to understand the generalizability of the framework. In the external dataset, our segmentation model achieved a Dice score of 0.92 (95% CI: 0.78, 1.00), and our classification model achieved an area under the receiver operating characteristic curve of 0.84 (95% CI: 0.79, 0.89). Our findings highlight the potential benefits of applying artificial intelligence models in NAFLD assessment.
Neural FIM for learning Fisher information metrics from point cloud data
Oluwadamilola Fasina
Guillaume Huguet
Alexander Tong
Yanlei Zhang
Maximilian Nickel
Ian Adelstein
Although data diffusion embeddings are ubiquitous in unsupervised learning and have proven to be a viable technique for uncovering the under… (voir plus)lying intrinsic geometry of data, diffusion embeddings are inherently limited due to their discrete nature. To this end, we propose neural FIM, a method for computing the Fisher information metric (FIM) from point cloud data - allowing for a continuous manifold model for the data. Neural FIM creates an extensible metric space from discrete point cloud data such that information from the metric can inform us of manifold characteristics such as volume and geodesics. We demonstrate Neural FIM’s utility in selecting parameters for the PHATE visualization method as well as its ability to obtain information pertaining to local volume illuminating branching points and cluster centers embeddings of a toy dataset and two single-cell datasets of IPSC reprogramming and PBMCs (immune cells).
Pretrained Language Models to Solve Graph Tasks in Natural Language
Frederik Wenkel
Boris Knyazev
Pretrained large language models (LLMs) are powerful learners in a variety of language tasks. We explore if LLMs can learn from graph-struct… (voir plus)ured data when the graphs are described using natural language. We explore data augmentation and pretraining specific to the graph domain and show that LLMs such as GPT-2 and GPT-3 are promising alternatives to graph neural networks.
Simulation-Free Schrödinger Bridges via Score and Flow Matching
Alexander Tong
Nikolay Malkin
Kilian FATRAS
Lazar Atanackovic
Yanlei Zhang
Guillaume Huguet
We present simulation-free score and flow matching ([SF]…
Geometry Regularized Autoencoders
Andres F. Duque Correa
Sacha Morin
Kevin R. Moon
A fundamental task in data exploration is to extract low dimensional representations that capture intrinsic geometry in data, especially for… (voir plus) faithfully visualizing data in two or three dimensions. Common approaches use kernel methods for manifold learning. However, these methods typically only provide an embedding of the input data and cannot extend naturally to new data points. Autoencoders have also become popular for representation learning. While they naturally compute feature extractors that are extendable to new data and invertible (i.e., reconstructing original features from latent representation), they often fail at representing the intrinsic data geometry compared to kernel-based manifold learning. We present a new method for integrating both approaches by incorporating a geometric regularization term in the bottleneck of the autoencoder. This regularization encourages the learned latent representation to follow the intrinsic data geometry, similar to manifold learning algorithms, while still enabling faithful extension to new data and preserving invertibility. We compare our approach to autoencoder models for manifold learning to provide qualitative and quantitative evidence of our advantages in preserving intrinsic structure, out of sample extension, and reconstruction. Our method is easily implemented for big-data applications, whereas other methods are limited in this regard.
Identifying Critical Neurons in ANN Architectures using Mixed Integer Programming
Mostafa ElAraby
Data Imputation with an Autoencoder and MAGIC
Devin Eddington
Andres Felipe Duque Correa
Kevin R. Moon
Missing data is a common problem in many applications. Imputing missing values is a challenging task, as the imputations need to be accurate… (voir plus) and robust to avoid introducing bias in downstream analysis. In this paper, we propose an ensemble method that combines the strengths of a manifold learning-based imputation method called MAGIC and an autoencoder deep learning model. We call our method Deep MAGIC. Deep MAGIC is trained on a linear combination of the mean squared error of the original data and the mean squared error of the MAGIC-imputed data. Experimental results on three benchmark datasets show that Deep MAGIC outperforms several state-of-the-art imputation methods, demonstrating its effectiveness and robustness in handling large amounts of missing data.