Portrait de Guillaume Dumas

Guillaume Dumas

Membre académique associé
Professeur agrégé, Université de Montréal, Département de psychiatrie et d’addictologie
Professeur adjoint, McGill University, Département de psychiatrie
Sujets de recherche
Apprentissage automatique médical
Apprentissage par renforcement
Apprentissage profond
Biologie computationnelle
Neurosciences computationnelles
Systèmes dynamiques
Théorie de l'apprentissage automatique
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Google Scholar
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Biographie

Guillaume Dumas est professeur agrégé de psychiatrie computationnelle à la Faculté de médecine de l'Université de Montréal et chercheur principal du laboratoire de psychiatrie de précision et de physiologie sociale du Centre de recherche du CHU Sainte-Justine. Il est titulaire de la chaire IVADO IA en santé mentale et chercheur-boursier junior 1 du Fonds de recherche du Québec - Santé (FRQS) dans le domaine de l’ IA en santé et de la santé numérique. En 2023, il a été retenu dans le cadre du Programme des chercheurs mondiaux CIFAR-Azrieli pour le programme de recherche Cerveau, esprit et conscience. Il a également été nommé parmi les Futurs leaders canadiens de la recherche sur le cerveau par la Fondation Brain Canada.

Il a auparavant été chercheur permanent en neurosciences et en biologie computationnelle à l'Institut Pasteur (Paris, France), ainsi que chercheur postdoctoral au Center for Complex Systems and Brain Sciences à l’Université Florida Atlantic (FAU), aux États-Unis. Il est titulaire d'un diplôme d'ingénieur en ingénierie avancée et informatique (École centrale Paris), de deux masters (physique théorique, Université Paris-Saclay; sciences cognitives, ENS/EHESS/Paris 5) et d'un doctorat en neurosciences cognitives (Sorbonne Université).

Ses recherches visent à combiner l’intelligence artificielle, les neurosciences cognitives et la médecine numérique à travers un programme interdisciplinaire suivant deux axes principaux :

- L’intelligence artificielle en santé mentale, par la création de nouveaux algorithmes pour étudier le développement de l'architecture cognitive humaine et pour fournir une médecine personnalisée en neuropsychiatrie grâce à des données allant du génome à celles des téléphones intelligents;

- Les neurosciences sociales en intelligence artificielle, par la traduction de la recherche fondamentale sur le cerveau et le formalisme des systèmes dynamiques en des modèles hybrides neurocomputationnels et d’apprentissage automatique (NeuroML) et de nouvelles architectures présentant des capacités d'apprentissage social (NeuroIA Sociale et IHM).

Étudiants actuels

Saskia Helbling
Postdoctorat - UdeM
Site web
Github
Google Scholar
Nadine Mohamed
Maîtrise recherche - UdeM
Rémy Ramadour
Visiteur de recherche indépendant - CHU Sainte Justine / Université de Montréal
Site web
Github
Mahta Ramezanian
Maîtrise recherche - UdeM
Superviseur⋅e principal⋅e :
Irina Rish
Pascal Tikeng Notsawo
Doctorat - UdeM
Superviseur⋅e principal⋅e :
Guillaume Rabusseau
Site web
Github
Google Scholar

Publications

Parsing Autism Heterogeneity: Transcriptomic Subgrouping of Imaging-Derived Phenotypes in Autism.
Johanna Leyhausen
Caroline Gurr
Lisa M. Berg
Hanna Seelemeyer
Bassem Hermila
Tim Schäfer
Andreas Chiocchetti
Charlotte M. Pretzsch
Eva Loth
Beth Oakley
Jan K. Buitelaar
Christian Beckmann
Tony Charman
Thomas Bourgeron
Eli Barthome
Tobias Banaschewski
Jumana Ahmad
Sara Ambrosino
Bonnie Auyeung
Simon Baron-Cohen … (voir 56 de plus)
Sarah Baumeister
Sven Bölte
Carsten Bours
Michael Brammer
Daniel Brandeis
Claudia Brogna
Yvette de Bruijn
Bhismadev Chakrabarti
Ineke Cornelissen
Daisy Crawley
Flavio Dell’Acqua
Guillaume Dumas
Sarah Durston
Christine Ecker
Jessica Faulkner
Vincent Frouin
Pilar Garcés
David Goyard
Lindsay Ham
Hannah Hayward
Joerg F. Hipp
Rosemary Holt
Mark Johnson
Emily J. H. Jones
Prantik Kundu
Meng-Chuan Lai
Xavier Liogier D’ardhuy
Michael V. Lombardo
David J. Lythgoe
René Mandl
Andre Marquand
Luke Mason
Maarten Mennes
Andreas Meyer-Lindenberg
Carolin Moessnang
Nico Bast
Larry O’Dwyer
Marianne Oldehinkel
Bob Oranje
Gahan Pandina
Antonio Persico
Barbara Ruggeri
Amber N. V. Ruigrok
Jessica Sabet
Roberto Sacco
Antonia San José Cáceres
Emily Simonoff
Will Spooren
Julian Tillmann
Roberto Toro
Heike Tost
Jack Waldman
Steve C. R. Williams
Caroline Wooldridge
Marcel P. Zwiers
Declan Murphy
2025-06-30
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging (publié)
doi.org
Inter-brain Synchronization in the Alpha Band during Minimal Tactile Interaction
Chen Lam Loh
Leonardo Zapata-Fonseca
Mark M. James
Guillaume Dumas
Tom Froese
Recently the minimal requirements for inter-brain coupling have attracted attention. Moreover, researchers have found that brains can couple… (voir plus) not only when individuals are in the same space, but also during technologically mediated interactions. Here we investigate whether inter-brain synchronization occurs when both conditions of spatial isolation and minimal interaction are satisfied. In particular, we use a real-time interaction paradigm, the Perceptual Crossing Experiment where individuals must locate their partners in a minimal virtual space using tactile stimuli alone. We report novel findings that contribute to our understanding of inter-brain synchronization and the minimal conditions of social interaction in virtual spaces : 1)inter-brain synchronization is present in the Alpha band during online minimal interaction, 2)five behavioral patterns and three inter-brain patterns can be found in the PCE and 3)different behavioral patterns in the interaction environment recruited different inter-brain networks such that frontal-fronto-central synchrony occurs when people are further apart in space, interacting with a multitude of objects. These findings have important implications for the understanding of social interaction processes, such that inter-brain coupling can occur even without extensive communication channels.
2025-06-23
bioRxiv (prépublication)
doi.org
Impact de l'antibiothérapie par Daptomycine dans le traitement des bactériémies à Enterococcus faecium en réanimation : l'étude rétrospective multicentrique ENTERODAPTO.
S. Herbel
Guillaume Dumas
L. Chantelot
J. Massol
Q. Moyon
J. Ricard
E. Azoulay
C. Hauw-Berlemont
E. Maury
T. Urbina
2025-05-31
Médecine et Maladies Infectieuses Formation (publié)
doi.org
A systematic review of hyperscanning in clinical encounters
Lena Adel
Lisane Moses
Elisabeth Irvine
Kyle T Greenway
Guillaume Dumas
Michael Lifshitz
2025-05-31
Neuroscience and Biobehavioral Reviews (publié)
doi.org
Response letter to “Confounding by indication and exposure misclassification may undermine corticosteroid effect estimates in ICU patients with alcohol-related hepatitis”
Guillaume Dumas
Maxime Gasperment
Hafid AIT-OUFELLA
2025-05-23
Annals of Intensive Care (publié)
doi.org
Persistent signs of poisoning after massive drug ingestion: move the ultrasound probe to the stomach.
N. Lautrou-cabasson
H. Pirollet
C. Lombois
Guillaume Dumas
2025-05-14
Intensive Care Medicine (publié)
doi.org
Proceedings of 1st Workshop on Advancing Artificial Intelligence through Theory of Mind
Mouad Abrini
Omri Abend
Dina M. Acklin
Henny Admoni
Gregor Aichinger
Nitay Alon
Zahra Ashktorab
Ashish Atreja
Moises Auron
Alexander Aufreiter
Raghav Awasthi
Soumya Banerjee
Joseph Barnby
Rhea Basappa
Severin Bergsmann
Djallel Bouneffouf
Patrick Callaghan
Marc Cavazza
Thierry Chaminade
Sonia Chernova … (voir 88 de plus)
Mohamed Chetouan
Moumita Choudhury
Axel Cleeremans
J. Cywinski
Fabio Cuzzolin
Hokin Deng
N'yoma Diamond
C. D. Pasquasio
Guillaume Dumas
Max J. van Duijn
Mahapatra Dwarikanath
Qingying Gao
Ashok Goel
Rebecca R. Goldstein
Matthew C. Gombolay
Gabriel Enrique Gonzalez
Amar Halilovic
Tobias Halmdienst
Mahimul Islam
Julian Jara-Ettinger
Natalie Kastel
Renana Keydar
Ashish K. Khanna
Mahdi Khoramshahi
Jihyun Kim
Mihyeon Kim
Youngbin Kim
Senka Krivic
Nikita Krasnytskyi
Arun Kumar
Junehyoung Kwon
EunJu Lee
Shane Lee
Peter R. Lewis 0001
Xue Li
Yijiang Li
Michal Lewandowski
Nathan Lloyd
Matthew B. Luebbers
Dezhi Luo
Haiyun Lyu
Dwarikanath Mahapatra
Kamal Maheshwari
Mallika Mainali
P. Mathur
Patrick Mederitsch
Shuwa Miura
Manuel Preston de Miranda
Reuth Mirsky
Shreya Mishra
Nina M. Moorman
Katelyn Morrison
John Muchovej
Bernhard Nessler
Felix Nessler
Hieu Minh Jord Nguyen
Abby Ortego
F. Papay
Antoine Pasquali
Hamed Rahimi
C. Raghu
Amanda L. Royka
Stefan Sarkadi
Jaelle Scheuerman
Simon Schmid
Paul Schrater
Anik Sen
Zahra Sheikhbahaee
Ke Shi
Reid G. Simmons
Nishant Singh
Mason O. Smith
Ramira van der Meulen
Anthia Solaki
Haoran Sun
Viktor Szolga
Matthew E. Taylor
Travis Taylor
Sanne van Waveren
Juan David Vargas
R. Verbrugge
Eitan Wagner
Justin D. Weisz
Ximing Wen
William Yeoh
Wenlong Zhang
Michelle Zhao
Shlomo Zilberstein
2025-04-27
ArXiv (prépublication)
doi.org
arxiv.org
Cortical differences across psychiatric disorders and associated common and rare genetic variants
Kuldeep Kumar
Zhijie Liao
Jakub Kopal
Clara Moreau
Christopher R. K. Ching
Claudia Modenato
Will Snyder
Sayeh Kazem
Charles-Olivier Martin
C.O. Martin
Anne-Marie Bélanger
Valérie K. Fontaine
Khadije Jizi
Rune Boen
Guillaume Huguet
Zohra Saci
Leila Kushan
Ana I. Silva
Marianne B.M. van den Bree
David E.J. Linden … (voir 16 de plus)
Michael J. Owen
Jeremy Hall
Sarah Lippé
Guillaume Dumas
Bogdan Draganski
Laura Almasy
Sophia I. Thomopoulos
Neda Jahanshad
Ida E. Sønderby
Ole A. Andreassen
David C. Glahn
Armin Raznahan
Carrie Bearden
Tomáš Paus
Paul M. Thompson
Sébastien Jacquemont
2025-04-18
medRxiv (prépublication)
doi.org
Online HD-tRNS over the right temporoparietal junction modulates social inference but not motor coordination
Quentin Moreau
Vincent Chamberland
Lisane Moses
Gabriela Milanova
Guillaume Dumas
Social interactions are fundamental to human cognition, with the right temporoparietal junction (rTPJ) playing a key role in integrating mot… (voir plus)or coordination and social inference. While transcranial random noise stimulation (tRNS) is a promising technique for modulating cortical excitability in real time, its effect on dynamic social processes remains largely unexplored. This study applied high-definition tRNS (HD-tRNS) over the rTPJ during an interactive task to modulate motor coordination and social inference. Eighty neurotypical adults (49 female) were equally distributed across two experiments: Experiment 1, a block design with randomized active and sham stimulation blocks; or Experiment 2, a trial-by-trial design with intermixed stimulation protocols. Participants performed a coordination task with a covert virtual partner programmed to behave cooperatively or competitively. Kinematic data and self-reported attributions of humanness and cooperativeness were analyzed. The results showed that HD-tRNS over the rTPJ did not affect motor coordination or overall task performance in either experiment. However, in Experiment 1, active stimulation progressively reduced attributed humanness and cooperativeness toward the competitive virtual partner, suggesting enhanced detection of antagonistic intent. This gradual modulation of social inference was absent in Experiment 2, where frequent protocol switching likely disrupted the buildup of stimulation effects. Together, these findings highlight the rTPJ's causal role in self–other distinction, underscore the importance of stimulation protocol design in shaping social cognition, and support the exploration of targeted neuromodulation in clinical and developmental populations with atypical social cognition.
2025-04-18
eNeuro (publié)
doi.org
Contemporary review of critical illness following allogeneic hematopoietic stem cell transplant in adults.
Laveena Munshi
Guillaume Dumas
Bruno Ferreryro
Cristina Gutierrez
Boris Böll
Pedro Castro
Sanjay Chawla
Matteo Di Nardo
Antoine Lafarge
Colleen McEvoy
Djamel Mokart
Antonio Paulo Nassar
Judith Nelson
Frédéric Pène
Peter Schellongowski
Elie Azoulay
2025-04-15
Intensive Care Medicine (publié)
doi.org
Alcohol related hepatitis in intensive care units: clinical and biological spectrum and mortality risk factors: a multicenter retrospective study
Maxime Gasperment
Léa Duhaut
Nicolas Terzi
Côme Gerard
Luc Haudebourg
Alexandre Demoule
Mialy Randrianarisoa
Vincent Castelain
Sacha Sarfati
Fabienne Tamion
Charlene Le Moal
Christophe Guitton
Gabriel Preda
Arnaud Galbois
Thibault Vieille
Gaël Piton
Marika Rudler
Guillaume Dumas
Hafid AIT-OUFELLA
Background Alcohol related hepatitis is responsible for high morbidity and mortality, but little is known about the management of patients w… (voir plus)ith hepatitis specifically in intensive care units (ICU). Methods Retrospective study including patients with alcohol related hepatitis hospitalized in 9 French ICUs (2006–2017). Alcohol related hepatitis was defined histologically or by an association of clinical and biological criteria according to current guidelines. Results 187 patients (median age: 53 [43–60]; male: 69%) were included. A liver biopsy was performed in 51% of cases. Patients were admitted for impaired consciousness (71%), sepsis (64%), shock (44%), respiratory failure (37%). At admission, median SOFA and MELD scores were 10 [7–13] and 31 [26–40] respectively. 63% of patients received invasive mechanical ventilation, 62% vasopressors, and 36% renal replacement therapy. 66% of patients received corticosteroids, and liver transplantation was performed in 16 patients (8.5%). ICU and in-hospital mortality were 37% and 53% respectively. By multivariate analysis, ICU mortality was associated with SOFA score (without total bilirubin) (SHR 1.08 [1.02–1.14] per one-point increase), arterial lactate (SHR 1.08 [1.03–1.13] per 1 mmol/L) and MELD score (SHR 1.09 [1.04–1.14] per 1 point), while employment was associated with increased survival (HR 0.49 [0.28–0.86]). After propensity score weighting, the use of corticosteroids did not affect ICU mortality in the overall population but had a beneficial effect in the subgroup of patients with histological proof. Patient prognosis was also better in responders assessed by Lille score at day 7 (OR 6.67 [2.44–20.15], p  0.001). Conclusion Alcohol related hepatitis is a severe condition leading to high mortality in ICU patients. Severity of organ failure
2025-04-14
Annals of Intensive Care (publié)
doi.org
Genetic modulation of brain dynamics in neurodevelopmental disorders: the impact of copy number variations on resting-state EEG
Adrien E. E. Dubois
Elisabeth Audet-Duchesne
Inga Sophia Knoth
Charles-Olivier Martin
Khadije Jizi
Petra Tamer
Nadine Younis
Sébastien Jacquemont
Guillaume Dumas
Sarah Lippé
Research has shown that many copy number variations (CNVs) increase the risk of neurodevelopmental disorders (e.g., autism, ADHD, schizophre… (voir plus)nia). However, little is known about the effects of CNVs on brain development and function. Resting-state electroencephalography (EEG) is a suitable method to study the disturbances of neuronal functioning in CNVs. We aimed to determine whether there are resting-state EEG signatures that are characteristic of children with pathogenic CNVs. EEG resting-state brain activity of 109 CNV carriers (66 deletion carriers, 43 duplication carriers) aged 3 to 17 years was recorded for 4 minutes. To better account for developmental variations, EEG indices (power spectral density and functional connectivity) were corrected with a normative model estimated from 256 Healthy Brain Network controls. Results showed a decreased exponent of the aperiodic activity and a reduced alpha peak frequency in CNV carriers. Additionally, the study showed altered periodic components and connectivity in several frequency bands. Deletion and duplication carriers exhibited a similar overall pattern of deviations in spectral and connectivity measures, although the significance and effect sizes relative to the control group varied across frequency bands. Deletion and duplication carriers can be differentiated by their periodic power in the gamma band and connectivity in the low alpha band, with duplication carriers showing more disrupted alterations than deletion carriers. The distinctive alterations in spectral patterns were found to be most prominent during adolescence. The results suggest that CNV carriers show electrophysiological alterations compared to neurotypical controls, regardless of the gene dosage effect and their affected genomic region. At the same time, while duplications and deletions share common electrophysiological alterations, each exhibits distinct brain alteration signatures that reflect gene dosage-specific effects.
2025-04-09
Translational Psychiatry (publié)
doi.org