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Simon Lemieux

Alumni

Publications

Deep learning of chest X-rays can predict mechanical ventilation outcome in ICU-admitted COVID-19 patients
Daniel Gourdeau
Olivier Potvin
Jason Henry Biem
Lyna Abrougui
Patrick Archambault
Carl Chartrand-Lefebvre
Louis Dieumegarde
Louis Gagnon
Raphaelle Giguère
Alexandre Hains
Marie-Hélène Lévesque
Simon Nepveu
Lorne Rosenbloom
An Tang
Issac Yang
Nathalie Duchesne … (voir 1 de plus)
Simon Duchesne
Tracking and predicting COVID-19 radiological trajectory on chest X-rays using deep learning
Daniel Gourdeau
Olivier Potvin
Patrick Archambault
Carl Chartrand‐lefebvre
Louis Dieumegarde
Reza Forghani
Alexandre Hains
David Hornstein
Huy Khiem Le
Marie‐hélène Lévesque
Diego R. Martin
Lorne Rosenbloom
An Tang
Fabrizio Vecchio
Issac Y Yang
N. Duchesne
Simon Duchesne
Tracking and predicting COVID-19 radiological trajectory on chest X-rays using deep learning
Daniel Gourdeau
Olivier Potvin
Patrick Archambault
Carl Chartrand-Lefebvre
Louis Dieumegarde
Reza Forghani
Alexandre Hains
David Hornstein
Marie-Hélène Lévesque
Diego Martin
Lorne Rosenbloom
An Tang
Fabrizio Vecchio
Issac Yang
Nathalie Duchesne
Simon Duchesne
Tracking and predicting COVID-19 radiological trajectory on chest X-rays using deep learning
Daniel Gourdeau
Olivier Potvin
Patrick Archambault
Carl Chartrand-Lefebvre
Louis Dieumegarde
Reza Forghani
Alexandre Hains
David Hornstein
Marie-Hélène Lévesque
Diego Martin
Lorne Rosenbloom
An Tang
Fabrizio Vecchio
Issac Yang
Nathalie Duchesne
Simon Duchesne
Radiological findings on chest X-ray (CXR) have shown to be essential for the proper management of COVID-19 patients as the maximum severity… (voir plus) over the course of the disease is closely linked to the outcome. As such, evaluation of future severity from current CXR would be highly desirable. We trained a repurposed deep learning algorithm on the CheXnet open dataset (224,316 chest X-ray images of 65,240 unique patients) to extract features that mapped to radiological labels. We collected CXRs of COVID-19-positive patients from an open-source dataset (COVID-19 image data collection) and from a multi-institutional local ICU dataset. The data was grouped into pairs of sequential CXRs and were categorized into three categories: ‘Worse’, ‘Stable’, or ‘Improved’ on the basis of radiological evolution ascertained from images and reports. Classical machine-learning algorithms were trained on the deep learning extracted features to perform immediate severity evaluation and prediction of future radiological trajectory. Receiver operating characteristic analyses and Mann-Whitney tests were performed. Deep learning predictions between “Worse” and “Improved” outcome categories and for severity stratification were significantly different for three radiological signs and one diagnostic (‘Consolidation’, ‘Lung Lesion’, ‘Pleural effusion’ and ‘Pneumonia’; all P 0.05). Features from the first CXR of each pair could correctly predict the outcome category between ‘Worse’ and ‘Improved’ cases with a 0.81 (0.74–0.83 95% CI) AUC in the open-access dataset and with a 0.66 (0.67–0.64 95% CI) AUC in the ICU dataset. Features extracted from the CXR could predict disease severity with a 52.3% accuracy in a 4-way classification. Severity evaluation trained on the COVID-19 image data collection had good out-of-distribution generalization when testing on the local dataset, with 81.6% of intubated ICU patients being classified as critically ill, and the predicted severity was correlated with the clinical outcome with a 0.639 AUC. CXR deep learning features show promise for classifying disease severity and trajectory. Once validated in studies incorporating clinical data and with larger sample sizes, this information may be considered to inform triage decisions.
TRACKING AND PREDICTING COVID-19 RADIOLOGICAL TRAJECTORY USING DEEP LEARNING ON CHEST X-RAYS: INITIAL ACCURACY TESTING
Simon Duchesne
Olivier Potvin
Daniel Gourdeau
Patrick Archambault
Carl Chartrand-Lefebvre
Louis Dieumegarde
Reza Forghani
Alexandre Hains
David Hornstein
Marie-Hélène Lévesque
Diego Martin
Lorne Rosenbloom
An Tang
Fabrizio Vecchio
Issac Yang
Nathalie Duchesne
Theano: A Python framework for fast computation of mathematical expressions
Rami Al-rfou'
Amjad Almahairi
Christof Angermüller
Frédéric Bastien
Justin S. Bayer
A. Belikov
A. Belopolsky
Josh Bleecher Snyder
Paul F. Christiano
Marc-Alexandre Côté
Myriam Côté
Julien Demouth
Sander Dieleman
M'elanie Ducoffe
Ziye Fan
Mathieu Germain
Ian G Goodfellow
Matthew Graham
Balázs Hidasi
Arjun Jain
Kai Jia
Mikhail V. Korobov
Vivek Kulkarni
Pascal Lamblin
Eric Larsen
S. Lee
Simon-mark Lefrancois
J. Livezey
Cory R. Lorenz
Jeremiah L. Lowin
Qianli M. Ma
R. McGibbon
Mehdi Mirza
Alberto Orlandi
Colin Raffel
Daniel Renshaw
Matthew David Rocklin
Markus Dr. Roth
Peter Sadowski
John Salvatier
Jan Schlüter
John D. Schulman
Gabriel Schwartz
Iulian V. Serban
Samira Shabanian
Sigurd Spieckermann
S. Subramanyam
Gijs van Tulder
Sebastian Urban
Dustin J. Webb
M. Willson
Lijun Xue
Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficie… (voir plus)ntly. Since its introduction, it has been one of the most used CPU and GPU mathematical compilers - especially in the machine learning community - and has shown steady performance improvements. Theano is being actively and continuously developed since 2008, multiple frameworks have been built on top of it and it has been used to produce many state-of-the-art machine learning models. The present article is structured as follows. Section I provides an overview of the Theano software and its community. Section II presents the principal features of Theano and how to use them, and compares them with other similar projects. Section III focuses on recently-introduced functionalities and improvements. Section IV compares the performance of Theano against Torch7 and TensorFlow on several machine learning models. Section V discusses current limitations of Theano and potential ways of improving it.
Theano: A Python framework for fast computation of mathematical expressions
Rami Al-rfou'
Amjad Almahairi
Christof Angermüller
Frédéric Bastien
Justin S. Bayer
A. Belikov
A. Belopolsky
J. Bergstra
Josh Bleecher Snyder
Paul F. Christiano
Marc-Alexandre Côté
Myriam Côté
Julien Demouth
Sander Dieleman
M'elanie Ducoffe
Ziye Fan
Mathieu Germain
Ian J. Goodfellow
Matthew Graham
Balázs Hidasi
Arjun Jain
S'ebastien Jean
Kai Jia
Mikhail V. Korobov
Vivek Kulkarni
Pascal Lamblin
Eric P. Larsen
S. Lee
Simon-mark Lefrancois
J. Livezey
Cory R. Lorenz
Jeremiah L. Lowin
Qianli M. Ma
R. McGibbon
Mehdi Mirza
Alberto Orlandi
Colin Raffel
Daniel Renshaw
Matthew David Rocklin
Markus Dr. Roth
Peter Sadowski
John Salvatier
Jan Schlüter
John D. Schulman
Gabriel Schwartz
Iulian V. Serban
Samira Shabanian
Sigurd Spieckermann
S. Subramanyam
Gijs van Tulder
Joseph P. Turian
Sebastian Urban
Dustin J. Webb
M. Willson
Lijun Xue
Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficie… (voir plus)ntly. Since its introduction, it has been one of the most used CPU and GPU mathematical compilers - especially in the machine learning community - and has shown steady performance improvements. Theano is being actively and continuously developed since 2008, multiple frameworks have been built on top of it and it has been used to produce many state-of-the-art machine learning models. The present article is structured as follows. Section I provides an overview of the Theano software and its community. Section II presents the principal features of Theano and how to use them, and compares them with other similar projects. Section III focuses on recently-introduced functionalities and improvements. Section IV compares the performance of Theano against Torch7 and TensorFlow on several machine learning models. Section V discusses current limitations of Theano and potential ways of improving it.