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The SARS-CoV-2 (Covid-19) pandemic has caused significant strain on public health institutions around the world. Contact tracing is an essen… (voir plus)tial tool to change the course of the Covid-19 pandemic. Manual contact tracing of Covid-19 cases has significant challenges that limit the ability of public health authorities to minimize community infections. Personalized peer-to-peer contact tracing through the use of mobile apps has the potential to shift the paradigm. Some countries have deployed centralized tracking systems, but more privacy-protecting decentralized systems offer much of the same benefit without concentrating data in the hands of a state authority or for-profit corporations. Machine learning methods can circumvent some of the limitations of standard digital tracing by incorporating many clues and their uncertainty into a more graded and precise estimation of infection risk. The estimated risk can provide early risk awareness, personalized recommendations and relevant information to the user. Finally, non-identifying risk data can inform epidemiological models trained jointly with the machine learning predictor. These models can provide statistical evidence for the importance of factors involved in disease transmission. They can also be used to monitor, evaluate and optimize health policy and (de)confinement scenarios according to medical and economic productivity indicators. However, such a strategy based on mobile apps and machine learning should proactively mitigate potential ethical and privacy risks, which could have substantial impacts on society (not only impacts on health but also impacts such as stigmatization and abuse of personal data). Here, we present an overview of the rationale, design, ethical considerations and privacy strategy of `COVI,' a Covid-19 public peer-to-peer contact tracing and risk awareness mobile application developed in Canada.
The number of visually impaired or blind (VIB) people in the world is estimated at several hundred million. Based on a series of interviews … (voir plus)with the VIB and developers of assistive technology, this paper provides a survey of machine-learning based mobile applications and identifies the most relevant applications. We discuss the functionality of these apps, how they align with the needs and requirements of the VIB users, and how they can be improved with techniques such as federated learning and model compression. As a result of this study we identify promising future directions of research in mobile perception, micro-navigation, and content-summarization.
We study the challenges of applying deep learning to gene expression data. We find experimentally that there exists non-linear signal in the… (voir plus) data, however is it not discovered automatically given the noise and low numbers of samples used in most research. We discuss how gene interaction graphs (same pathway, protein-protein, co-expression, or research paper text association) can be used to impose a bias on a deep model similar to the spatial bias imposed by convolutions on an image. We explore the usage of Graph Convolutional Neural Networks coupled with dropout and gene embeddings to utilize the graph information. We find this approach provides an advantage for particular tasks in a low data regime but is very dependent on the quality of the graph used. We conclude that more work should be done in this direction. We design experiments that show why existing methods fail to capture signal that is present in the data when features are added which clearly isolates the problem that needs to be addressed.
In this work we explore how gene-gene interaction graphs can be used as a prior for the representation of a model to construct features base… (voir plus)d on known interactions between genes. Most existing machine learning work on graphs focuses on building models when data is confined to a graph structure. In this work we focus on using the information from a graph to build better representations in our models. We use the percolate task, determining if a path exists across a grid for a set of node values, as a proxy for gene pathways. We create variants of the percolate task to explore where existing methods fail. We test the limits of existing methods in order to determine what can be improved when applying these methods to a real task. This leads us to propose new methods based on Graph Convolutional Networks (GCN) that use pooling and dropout to deal with noise in the graph prior.
