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Publications
FedWeight: mitigating covariate shift of federated learning on electronic health records data through patients re-weighting
High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language… (voir plus) models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical domain adaptation, which remains challenging. An additional bottleneck is the unavailability and high sensitivity of clinical data. To address these challenges, we propose a novel framework for adapting SLMs into high-performing clinical models. We introduce the MediPhi collection of 3.8B-parameter SLMs developed with our novel framework: pre-instruction tuning of experts on relevant medical and clinical corpora (PMC, Medical Guideline, MedWiki, etc.), model merging, and clinical-tasks alignment. To cover most clinical tasks, we extended the CLUE benchmark to CLUE+, doubling its size. Our expert models deliver relative improvements on this benchmark over the base model without any task-specific fine-tuning: 64.3% on medical entities, 49.5% on radiology reports, and 44% on ICD-10 coding (outperforming GPT-4-0125 by 14%). We unify the expert models into MediPhi via model merging, preserving gains across benchmarks. Furthermore, we built the MediFlow collection, a synthetic dataset of 2.5 million high-quality instructions on 14 medical NLP tasks, 98 fine-grained document types, and JSON format support. Alignment of MediPhi using supervised fine-tuning and direct preference optimization achieves further gains of 18.9% on average.
Language model (LM) agents are increasingly used as autonomous decision-makers who need to actively gather information to guide their decisi… (voir plus)ons. A crucial cognitive skill for such agents is the efficient exploration and understanding of the causal structure of the world -- key to robust, scientifically grounded reasoning. Yet, it remains unclear whether LMs possess this capability or exhibit systematic biases leading to erroneous conclusions. In this work, we examine LMs' ability to explore and infer causal relationships, using the well-established"Blicket Test"paradigm from developmental psychology. We find that LMs reliably infer the common, intuitive disjunctive causal relationships but systematically struggle with the unusual, yet equally (or sometimes even more) evidenced conjunctive ones. This"disjunctive bias"persists across model families, sizes, and prompting strategies, and performance further declines as task complexity increases. Interestingly, an analogous bias appears in human adults, suggesting that LMs may have inherited deep-seated reasoning heuristics from their training data. To this end, we quantify similarities between LMs and humans, finding that LMs exhibit adult-like inference profiles (but not children-like). Finally, we propose a test-time sampling method which explicitly samples and eliminates hypotheses about causal relationships from the LM. This scalable approach significantly reduces the disjunctive bias and moves LMs closer to the goal of scientific, causally rigorous reasoning.
