Portrait of Yoshua Bengio

Yoshua Bengio

Core Academic Member
Canada CIFAR AI Chair
Full Professor, Université de Montréal
Research Topics
Causality
Computational Neuroscience
Deep Learning
Generative Models
Graph Neural Networks
Machine Learning Theory
Medical Machine Learning
Molecular Modeling
Natural Language Processing
Probabilistic Models
Reasoning
Recurrent Neural Networks
Reinforcement Learning
Representation Learning

Biography

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Yoshua Bengio is recognized worldwide as a leading expert in AI. He is most known for his pioneering work in deep learning, which earned him the 2018 A.M. Turing Award, “the Nobel Prize of computing,” with Geoffrey Hinton and Yann LeCun.

Bengio is a full professor at Université de Montréal, and the founder and scientific advisor of Mila – Quebec Artificial Intelligence Institute. He is also a senior fellow at CIFAR and co-directs its Learning in Machines & Brains program, serves as special advisor and founding scientific director of IVADO, and holds a Canada CIFAR AI Chair.

In 2019, Bengio was awarded the prestigious Killam Prize and in 2022, he was the most cited computer scientist in the world by h-index. He is a Fellow of the Royal Society of London, Fellow of the Royal Society of Canada, Knight of the Legion of Honor of France and Officer of the Order of Canada. In 2023, he was appointed to the UN’s Scientific Advisory Board for Independent Advice on Breakthroughs in Science and Technology.

Concerned about the social impact of AI, Bengio helped draft the Montréal Declaration for the Responsible Development of Artificial Intelligence and continues to raise awareness about the importance of mitigating the potentially catastrophic risks associated with future AI systems.

Current Students

Collaborating researcher - Cambridge University
Principal supervisor :
PhD - Université de Montréal
PhD - Université de Montréal
PhD - Université de Montréal
Collaborating Alumni - Université de Montréal
Collaborating researcher - Université de Montréal
Postdoctorate - Université de Montréal
Principal supervisor :
Collaborating researcher - KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Collaborating researcher - s.o.
PhD - Université de Montréal
Co-supervisor :
PhD - Université de Montréal
Principal supervisor :
Independent visiting researcher - Université de Montréal
Collaborating researcher - Ying Wu Coll of Computing
Collaborating researcher - University of Waterloo
Principal supervisor :
Postdoctorate - Université de Montréal
Postdoctorate - Université de Montréal
PhD - Université de Montréal
Principal supervisor :
Postdoctorate - Université de Montréal
Co-supervisor :
Collaborating Alumni - Université de Montréal
Co-supervisor :
Collaborating Alumni - Université de Montréal
Collaborating researcher - University of Cambridge
Collaborating Alumni - Université de Montréal
Co-supervisor :
PhD - Université de Montréal
Principal supervisor :
Collaborating researcher - Université de Montréal
Collaborating researcher - Université de Montréal
PhD - McGill University
Principal supervisor :
Collaborating Alumni - McGill University
Principal supervisor :

Publications

Mastering Rate based Curriculum Learning
Deriving Differential Target Propagation from Iterating Approximate Inverses
Predicting COVID-19 Pneumonia Severity on Chest X-ray With Deep Learning
Beiyi Shen
Almas F Abbasi
Hoshmand Kochi Mahsa
Marzyeh Ghassemi
Haifang Li
Tim Q Duong
Introduction The need to streamline patient management for coronavirus disease-19 (COVID-19) has become more pressing than ever. Chest X-ray… (see more)s (CXRs) provide a non-invasive (potentially bedside) tool to monitor the progression of the disease. In this study, we present a severity score prediction model for COVID-19 pneumonia for frontal chest X-ray images. Such a tool can gauge the severity of COVID-19 lung infections (and pneumonia in general) that can be used for escalation or de-escalation of care as well as monitoring treatment efficacy, especially in the ICU. Methods Images from a public COVID-19 database were scored retrospectively by three blinded experts in terms of the extent of lung involvement as well as the degree of opacity. A neural network model that was pre-trained on large (non-COVID-19) chest X-ray datasets is used to construct features for COVID-19 images which are predictive for our task. Results This study finds that training a regression model on a subset of the outputs from this pre-trained chest X-ray model predicts our geographic extent score (range 0-8) with 1.14 mean absolute error (MAE) and our lung opacity score (range 0-6) with 0.78 MAE. Conclusions These results indicate that our model’s ability to gauge the severity of COVID-19 lung infections could be used for escalation or de-escalation of care as well as monitoring treatment efficacy, especially in the ICU. To enable follow up work, we make our code, labels, and data available online.
Learning to Navigate the Synthetically Accessible Chemical Space Using Reinforcement Learning
Sai Krishna Gottipati
Boris Sattarov
Sufeng Niu
Yashaswi Pathak
Haoran Wei
Karam J. Thomas
Connor W. Coley
Over the last decade, there has been significant progress in the field of machine learning for de novo drug design, particularly in deep gen… (see more)erative models. However, current generative approaches exhibit a significant challenge as they do not ensure that the proposed molecular structures can be feasibly synthesized nor do they provide the synthesis routes of the proposed small molecules, thereby seriously limiting their practical applicability. In this work, we propose a novel forward synthesis framework powered by reinforcement learning (RL) for de novo drug design, Policy Gradient for Forward Synthesis (PGFS), that addresses this challenge by embedding the concept of synthetic accessibility directly into the de novo drug design system. In this setup, the agent learns to navigate through the immense synthetically accessible chemical space by subjecting commercially available small molecule building blocks to valid chemical reactions at every time step of the iterative virtual multi-step synthesis process. The proposed environment for drug discovery provides a highly challenging test-bed for RL algorithms owing to the large state space and high-dimensional continuous action space with hierarchical actions. PGFS achieves state-of-the-art performance in generating structures with high QED and penalized clogP. Moreover, we validate PGFS in an in-silico proof-of-concept associated with three HIV targets. Finally, we describe how the end-to-end training conceptualized in this study represents an important paradigm in radically expanding the synthesizable chemical space and automating the drug discovery process.
S2RMs: Spatially Structured Recurrent Modules
Nasim Rahaman
Muhammad Waleed Gondal
Manuel Wuthrich
Y. Sharma
Bernhard Schölkopf
Compositional Generalization by Factorizing Alignment and Translation
Jacob Russin
R. O’Reilly
Exploiting Syntactic Structure for Better Language Modeling: A Syntactic Distance Approach
Wenyu Du
Timothy J. O’Donnell
Yue Zhang
It is commonly believed that knowledge of syntactic structure should improve language modeling. However, effectively and computationally eff… (see more)iciently incorporating syntactic structure into neural language models has been a challenging topic. In this paper, we make use of a multi-task objective, i.e., the models simultaneously predict words as well as ground truth parse trees in a form called "syntactic distances", where information between these two separate objectives shares the same intermediate representation. Experimental results on the Penn Treebank and Chinese Treebank datasets show that when ground truth parse trees are provided as additional training signals, the model is able to achieve lower perplexity and induce trees with better quality.
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition
The recent development of sequencing technologies revolutionized our understanding of the inner workings of the cell as well as the way dise… (see more)ase is treated. A single RNA sequencing (RNA-Seq) experiment, however, measures tens of thousands of parameters simultaneously. While the results are information rich, data analysis provides a challenge. Dimensionality reduction methods help with this task by extracting patterns from the data by compressing it into compact vector representations. We present the factorized embeddings (FE) model, a self-supervised deep learning algorithm that learns simultaneously, by tensor factorization, gene and sample representation spaces. We ran the model on RNA-Seq data from two large-scale cohorts and observed that the sample representation captures information on single gene and global gene expression patterns. Moreover, we found that the gene representation space was organized such that tissue-specific genes, highly correlated genes as well as genes participating in the same GO terms were grouped. Finally, we compared the vector representation of samples learned by the FE model to other similar models on 49 regression tasks. We report that the representations trained with FE rank first or second in all of the tasks, surpassing, sometimes by a considerable margin, other representations. A toy example in the form of a Jupyter Notebook as well as the code and trained embeddings for this project can be found at: https://github.com/TrofimovAssya/FactorizedEmbeddings. Supplementary data are available at Bioinformatics online.
Object Files and Schemata: Factorizing Declarative and Procedural Knowledge in Dynamical Systems
Sergey Levine
Charles Blundell
Michael Mozer
Image-to-image Mapping with Many Domains by Sparse Attribute Transfer
Rethinking Distributional Matching Based Domain Adaptation
Bin Li
Yezhen Wang
Tong Che
Shanghang Zhang
Sicheng Zhao
Pengfei Xu
Wenzhen Zhou
Kurt W. Keutzer
Domain adaptation (DA) is a technique that transfers predictive models trained on a labeled source domain to an unlabeled target domain, wit… (see more)h the core difficulty of resolving distributional shift between domains. Currently, most popular DA algorithms are based on distributional matching (DM). However in practice, realistic domain shifts (RDS) may violate their basic assumptions and as a result these methods will fail. In this paper, in order to devise robust DA algorithms, we first systematically analyze the limitations of DM based methods, and then build new benchmarks with more realistic domain shifts to evaluate the well-accepted DM methods. We further propose InstaPBM, a novel Instance-based Predictive Behavior Matching method for robust DA. Extensive experiments on both conventional and RDS benchmarks demonstrate both the limitations of DM methods and the efficacy of InstaPBM: Compared with the best baselines, InstaPBM improves the classification accuracy respectively by
HNHN: Hypergraph Networks with Hyperedge Neurons
Yihe Dong
W. Sawin