Publications

On the Identifiability of Causal Abstractions

Sékou-Oumar Kaba

Causal representation learning (CRL) enhances machine learning models' robustness and generalizability by learning structural causal models … (voir plus)associated with data-generating processes. We focus on a family of CRL methods that uses contrastive data pairs in the observable space, generated before and after a random, unknown intervention, to identify the latent causal model. (Brehmer et al., 2022) showed that this is indeed possible, given that all latent variables can be intervened on individually. However, this is a highly restrictive assumption in many systems. In this work, we instead assume interventions on arbitrary subsets of latent variables, which is more realistic. We introduce a theoretical framework that calculates the degree to which we can identify a causal model, given a set of possible interventions, up to an abstraction that describes the system at a higher level of granularity.

2025-04-23

Proceedings of The 28th International Conference on Artificial Intelligence and Statistics (publié)

doi.org

openreview.net

LLMs are Greedy Agents: Effects of RL Fine-tuning on Decision-Making Abilities

Thomas Schmied

Jörg Bornschein

Jordi Grau-Moya

Markus Wulfmeier

Razvan Pascanu

2025-04-22

ArXiv (prépublication)

arxiv.org

Neural Kinematic Bases for Fluids

Yibo Liu

Paul Kry

Kenny Erleben

Noam Aigerman

Sune Darkner

Teseo Schneider

2025-04-22

ArXiv (prépublication)

arxiv.org

Refining sequence-to-expression modelling with chromatin accessibility

Orsolya Lapohos

Gregory Fonseca

Amin Emad

2025-04-21

bioRxiv (prépublication)

doi.org

Cortical differences across psychiatric disorders and associated common and rare genetic variants

Kuldeep Kumar

Zhijie Liao

Jakub Kopal

Clara Moreau

Christopher R. K. Ching

Claudia Modenato

Will Snyder

Sayeh Kazem

Charles-Olivier Martin

C.O. Martin

Anne-Marie Bélanger

Valérie K. Fontaine

Khadije Jizi

Rune Boen

Guillaume Huguet

Zohra Saci

Leila Kushan

Ana I. Silva

Marianne B.M. van den Bree

David E.J. Linden … (voir 16 de plus)

Michael J. Owen

Jeremy Hall

Sarah Lippé

Guillaume Dumas

Bogdan Draganski

Laura Almasy

Sophia I. Thomopoulos

Neda Jahanshad

Ida E. Sønderby

Ole A. Andreassen

David C. Glahn

Armin Raznahan

Carrie Bearden

Tomas Paus

Paul M. Thompson

Sébastien Jacquemont

2025-04-19

medRxiv (prépublication)

doi.org

Impact of Reducing Time Lived With Colostomies on Social Stigma Affecting Children With Anorectal Malformations in Southwestern Uganda.

Felix Oyania

Caroline Q. Stephens

Sarah Ullrich

Meera Kotagal

Amy M. Shui

Caleb Tuhumwire

G. Rukundo

Joseph Ngonzi

Ava Yap

Francis Bajunirwe

Dan Poenaru

Doruk Ozgediz

BACKGROUND The social stigma of families of children living with colostomies due to anorectal malformation (ARM) is significant in low-incom… (voir plus)e countries (LICs). Improved access to pediatric surgery has resulted in more 1-stage ARM procedures in Southwestern Uganda, avoiding colostomy creation, but the impact on social stigma experienced by families is unknown. We hypothesized that this change would decrease the social stigma experienced by families. METHODS A single-center mixed retrospective and prospective cohort study with combined qualitative data of families of children with ARM who underwent corrective surgery compared the stigma experienced by those with colostomies to those without. The Kilifi Stigma Scale of Epilepsy (KSSE) was used to assess social stigma. Multivariable regression analysis assessed differences in the stigma experienced, controlling for age at diagnosis, rurality, distance traveled, sex, and parental education. Subgroup analysis assessed the impact of colostomy duration on stigma, stratified over parental education. RESULTS Patient/family dyads with 238 ARM were included; 177 (74%) received a colostomy. Most patients were male (51%), lived in rural areas (71%), and had parents with primary school education (65%). For those without a colostomy, the median KSSE was 0 (Q1-Q3 0-0), compared to 11 (Q1-Q3 3-20) for colostomy. On multivariable analysis, after controlling for age at diagnosis, rurality, distance traveled, sex, and parental education attainment, families of patients with ARM who received a colostomy had a median KSSE score 7.8 points higher than those who did not receive a colostomy (coefficient 7.78, 95% 3.14-12.43, and p = 0.001). When the duration of colostomy (in years) was examined, the median KSSE score increased by 1.58 points for each additional year for a patient who had a colostomy (IRR 1.58, 95% CI: 0.76-2.40, and p 0.001). CONCLUSION Adopting a 1-stage ARM repair for the select types, which avoids colostomy creation, significantly reduces the exper

2025-04-19

World Journal of Surgery (publié)

doi.org

Impact of Reducing Time Lived With Colostomies on Social Stigma Affecting Children With Anorectal Malformations in Southwestern Uganda.

Felix Oyania

Caroline Q. Stephens

Sarah Ullrich

Meera Kotagal

Amy M. Shui

Caleb Tuhumwire

G. Rukundo

Joseph Ngonzi