Portrait of Yoshua Bengio

Yoshua Bengio

Core Academic Member
Canada CIFAR AI Chair
Full Professor, Université de Montréal
Research Topics
Causality
Computational Neuroscience
Deep Learning
Generative Models
Graph Neural Networks
Machine Learning Theory
Medical Machine Learning
Molecular Modeling
Natural Language Processing
Probabilistic Models
Reasoning
Recurrent Neural Networks
Reinforcement Learning
Representation Learning

Biography

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Yoshua Bengio is recognized worldwide as a leading expert in AI. He is most known for his pioneering work in deep learning, which earned him the 2018 A.M. Turing Award, “the Nobel Prize of computing,” with Geoffrey Hinton and Yann LeCun.

Bengio is a full professor at Université de Montréal, and the founder and scientific advisor of Mila – Quebec Artificial Intelligence Institute. He is also a senior fellow at CIFAR and co-directs its Learning in Machines & Brains program, serves as special advisor and founding scientific director of IVADO, and holds a Canada CIFAR AI Chair.

In 2019, Bengio was awarded the prestigious Killam Prize and in 2022, he was the most cited computer scientist in the world by h-index. He is a Fellow of the Royal Society of London, Fellow of the Royal Society of Canada, Knight of the Legion of Honor of France and Officer of the Order of Canada. In 2023, he was appointed to the UN’s Scientific Advisory Board for Independent Advice on Breakthroughs in Science and Technology.

Concerned about the social impact of AI, Bengio helped draft the Montréal Declaration for the Responsible Development of Artificial Intelligence and continues to raise awareness about the importance of mitigating the potentially catastrophic risks associated with future AI systems.

Current Students

Collaborating researcher - Cambridge University
Principal supervisor :
PhD - Université de Montréal
PhD - Université de Montréal
PhD - Université de Montréal
Collaborating Alumni - Université de Montréal
Postdoctorate - Université de Montréal
Principal supervisor :
Collaborating researcher - Université de Montréal
Collaborating researcher - KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Collaborating researcher - s.o.
PhD - Université de Montréal
Co-supervisor :
PhD - Université de Montréal
Principal supervisor :
Independent visiting researcher - Université de Montréal
Collaborating researcher - Ying Wu Coll of Computing
Collaborating researcher - University of Waterloo
Principal supervisor :
Postdoctorate - Université de Montréal
Postdoctorate - Université de Montréal
PhD - Université de Montréal
Principal supervisor :
Postdoctorate - Université de Montréal
Co-supervisor :
Collaborating Alumni - Université de Montréal
Co-supervisor :
Collaborating Alumni - Université de Montréal
Collaborating researcher - University of Cambridge
Collaborating Alumni - Université de Montréal
Co-supervisor :
PhD - Université de Montréal
Principal supervisor :
Collaborating researcher - Université de Montréal
Collaborating researcher - Université de Montréal
PhD - McGill University
Principal supervisor :
Collaborating Alumni - McGill University
Principal supervisor :

Publications

CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
Tariq Daouda
Maude Dumont-Lagacé
Albert Feghaly
Yahya Benslimane
Rebecca Panes
Mathieu Courcelles
Mohamed Benhammadi
Lea Harrington
Pierre Thibault
François Major
Étienne Gagnon
Claude Perreault
MHC-I associated peptides (MAPs) are small fragments of intracellular proteins presented at the surface of cells and used by the immune syst… (see more)em to detect and eliminate cancerous or virus-infected cells. While it is theoretically possible to predict which portions of the intracellular proteins will be naturally processed by the cells to ultimately reach the surface, current methodologies have prohibitively high false discovery rates. Here we introduce an artificial neural network called Codon Arrangement MAP Predictor (CAMAP) which integrates information from mRNA-to-protein translation to other factors regulating MAP biogenesis (e.g. MAP ligand score and transcript expression levels) to improve MAP prediction accuracy. While most MAP predictive approaches focus on MAP sequences per se, CAMAP’s novelty is to analyze the MAP-flanking mRNA sequences, thereby providing completely independent information for MAP prediction. We show on several datasets that the integration of CAMAP scores with other known factors involved in MAP presentation (i.e. MAP ligand score and mRNA expression) significantly improves MAP prediction accuracy, and further validate CAMAP learned features using anin-vitroassay. These findings may have major implications for the design of vaccines against cancers and viruses, and in times of pandemics could accelerate the identification of relevant MAPs of viral origins.
CAMAP: Artificial neural networks unveil the role of 1 codon arrangement in modulating MHC-I peptides 2 presentation discovery of minor histocompatibility with
Tariq Daouda
Maude Dumont-Lagacé
Albert Feghaly
Yahya Benslimane
6. Rébecca
Panes
Mathieu Courcelles
Mohamed Benhammadi
Lea Harrington
Pierre Thibault
François Major
Étienne Gagnon
S. Lemieux
Claude Perreault
30 MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and 31 neoplastic cells by CD8 T cells. However… (see more), accurately predicting the MAP repertoire remains 32 difficult, because only a fraction of the transcriptome generates MAPs. In this study, we 33 investigated whether codon arrangement (usage and placement) regulates MAP biogenesis. We 34 developed an artificial neural network called Codon Arrangement MAP Predictor (CAMAP), 35 predicting MAP presentation solely from mRNA sequences flanking the MAP-coding codons 36 (MCCs), while excluding the MCC per se . CAMAP predictions were significantly more accurate 37 when using original codon sequences than shuffled codon sequences which reflect amino acid 38 usage. Furthermore, predictions were independent of mRNA expression and MAP binding affinity 39 to MHC-I molecules and applied to several cell types and species. Combining MAP ligand scores, 40 transcript expression level and CAMAP scores was particularly useful to increaser MAP prediction 41 accuracy. Using an in vitro assay, we showed that varying the synonymous codons in the regions 42 flanking the MCCs (without changing the amino acid sequence) resulted in significant modulation 43 of MAP presentation at the cell surface. Taken together, our results demonstrate the role of codon 44 arrangement in the regulation of MAP presentation and support integration of both translational 45 and post-translational events in predictive algorithms to ameliorate modeling of the 46 immunopeptidome. 47 48 49 they modulated the levels of SIINFEKL presentation in both constructs, but enhanced translation efficiency could only be detected for OVA-RP. These data show that codon arrangement can modulate MAP presentation strength without any changes in the amino
CAMAP: Artificial neural networks unveil the role of 1 codon arrangement in modulating MHC-I peptides 2 presentation
Tariq Daouda
Maude Dumont-Lagacé
Albert Feghaly
Yahya Benslimane
6. Rébecca
Panes
Mathieu Courcelles
Mohamed Benhammadi
Lea Harrington
Pierre Thibault
François Major
Étienne Gagnon
S. Lemieux
Claude Perreault
30 MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and 31 neoplastic cells by CD8 T cells. However… (see more), accurately predicting the MAP repertoire remains 32 difficult, because only a fraction of the transcriptome generates MAPs. In this study, we 33 investigated whether codon arrangement (usage and placement) regulates MAP biogenesis. We 34 developed an artificial neural network called Codon Arrangement MAP Predictor (CAMAP), 35 predicting MAP presentation solely from mRNA sequences flanking the MAP-coding codons 36 (MCCs), while excluding the MCC per se . CAMAP predictions were significantly more accurate 37 when using original codon sequences than shuffled codon sequences which reflect amino acid 38 usage. Furthermore, predictions were independent of mRNA expression and MAP binding affinity 39 to MHC-I molecules and applied to several cell types and species. Combining MAP ligand scores, 40 transcript expression level and CAMAP scores was particularly useful to increaser MAP prediction 41 accuracy. Using an in vitro assay, we showed that varying the synonymous codons in the regions 42 flanking the MCCs (without changing the amino acid sequence) resulted in significant modulation 43 of MAP presentation at the cell surface. Taken together, our results demonstrate the role of codon 44 arrangement in the regulation of MAP presentation and support integration of both translational 45 and post-translational events in predictive algorithms to ameliorate modeling of the 46 immunopeptidome. 47 48 49 they modulated the levels of SIINFEKL presentation in both constructs, but enhanced translation efficiency could only be detected for OVA-RP. These data show that codon arrangement can modulate MAP presentation strength without any changes in the amino
Cooperative Semi-Supervised Transfer Learning of Machine Reading Comprehension
Oliver Bender
Franz Josef Och
R´ejean Ducharme
P Vincent
Kevin Clark
Quoc Minh-Thang Luong
V. Le
Jacob Devlin
Ming-Wei Chang
Kenton Lee
Adam Fisch
Alon Talmor
Robin Jia
Minjoon Seo
Michael R. Glass
A. Gliozzo
Rishav Chakravarti
Ian J Goodfellow
Mehdi Mirza
Serhii Havrylov
Ivan Titov. 2017
Emergence
Jun-Tao He
Jiatao Gu
Jiajun Shen
Marc’Aurelio
Matthew Henderson
I. Casanueva
Nikola Mrkˇsi´c
Pei-hao Su
Tsung-Hsien Wen
Ivan Vuli´c
Yi Tay
Che Zheng
Dara Bahri
Donald
Metzler Aaron
Courville
Structformer
Ashish Vaswani
Noam M. Shazeer
Niki Parmar
Thomas Wolf
Lysandre Debut
Julien Victor Sanh
Clement Chaumond
Anthony Delangue
Pier-339 Moi
Tim ric Cistac
R´emi Rault
Morgan Louf
Qizhe Xie
Eduard H. Hovy
Silei Xu
Sina Jandaghi Semnani
Giovanni Campagna
Pretrained language models have significantly 001 improved the performance of down-stream 002 language understanding tasks, including ex-00… (see more)3 tractive question answering, by providing 004 high-quality contextualized word embeddings. 005 However, training question answering models 006 still requires large amounts of annotated data 007 for specific domains. In this work, we pro-008 pose a cooperative, self-play learning frame-009 work, REGEX, for automatically generating 010 more non-trivial question-answer pairs to im-011 prove model performance. REGEX is built 012 upon a masked answer extraction task with an 013 interactive learning environment containing an 014 answer entity REcognizer, a question Gener-015 ator, and an answer EXtractor. Given a pas-016 sage with a masked entity, the generator gen-017 erates a question around the entity, and the 018 extractor is trained to extract the masked en-019 tity with the generated question and raw texts. 020 The framework allows the training of question 021 generation and answering models on any text 022 corpora without annotation. We further lever-023 age a reinforcement learning technique to re-024 ward generating high-quality questions and to 025 improve the answer extraction model’s perfor-026 mance. Experiment results show that REGEX 027 outperforms the state-of-the-art (SOTA) pre-028 trained language models and transfer learning 029 approaches on standard question-answering 030 benchmarks, and yields the new SOTA per-031 formance under given model size and transfer 032 learning settings. 033
Episodes Meta Sequence S 2 Fast Update Slow Update Fast Update Slow Update
Nan Rosemary Ke
Bernhard Schölkopf
Decomposing knowledge into interchangeable pieces promises a generalization advantage when there are changes in distribution. A learning age… (see more)nt interacting with its environment is likely to be faced with situations requiring novel combinations of existing pieces of knowledge. We hypothesize that such a decomposition of knowledge is particularly relevant for being able to generalize in a systematic manner to out-of-distribution changes. To study these ideas, we propose a particular training framework in which we assume that the pieces of knowledge an agent needs and its reward function are stationary and can be re-used across tasks. An attention mechanism dynamically selects which modules can be adapted to the current task, and the parameters of the selected modules are allowed to change quickly as the learner is confronted with variations in what it experiences, while the parameters of the attention mechanisms act as stable, slowly changing, metaparameters.We focus on pieces of knowledge captured by an ensemble of modules sparsely communicating with each other via a bottleneck of attention. We find that meta-learning the modular aspects of the proposed system greatly helps in achieving faster adaptation in a reinforcement learning setup involving navigation in a partially observed grid world with image-level input. We also find that reversing the role of parameters and meta-parameters does not work nearly as well, suggesting a particular role for fast adaptation of the dynamically selected modules.
Explaining by Analogy: Case-based Abductive Natural Language Inference
Graham Spinks
Marie Francine
Peter Clark
Isaac Cowhey
Oren Etzioni
Tushar Khot
Rajarshi Das
Ameya Godbole
Shehzaad Dhuliawala
Manzil Zaheer
Andrew McCallum
Dung Ngoc Thai
Ameya
Ethan Godbole
Jay-Yoon Perez
Lee
Lizhen
Ramón López De Mántaras
David Mcsherry … (see 37 more)
David Bridge
Barry Leake
Susan Smyth
Craw.
Boi
Maryalice Faltings
Michael T Maher
Ken-552 Cox
Dorottya Demszky
Kelvin Guu
Percy Liang
Jacob Devlin
Ming-Wei Chang
Kenton Lee
Daniel Fried
Peter Jansen
Gus Hahn-Powell
Higher-575
Rebecca Emilie Sharp
M. Surdeanu
Zhengnan Xie
Sebastian Thiem
Jaycie Ryrholm Martin
Eliz-721 abeth Wainwright
Steven Marmorstein
Wenhan Xiong
Xiang Lorraine Li
Srini Iyer
Jingfei Du
Vikas Yadav
Steven Bethard
Zhilin Yang
Peng Qi
William W Cohen
Russ Salakhutdinov
Existing accounts of explanation emphasise 001 the role of prior experience and analogy in 002 the solution of new problems. However, most 0… (see more)03 of the contemporary models for multi-hop tex-004 tual inference construct explanations consider-005 ing each test case in isolation. This paradigm 006 is known to suffer from semantic drift, which 007 causes the construction of spurious explana-008 tions leading to wrong predictions. In con-009 trast, we propose an abductive framework for 010 multi-hop inference that adopts the retrieve - 011 reuse - revise paradigm largely studied in case-012 based reasoning . Specifically, we present 013 ETNA ( E xplana t io n by A nalogy), a novel 014 model that addresses unseen inference prob-015 lems by retrieving and adapting prior expla-016 nations from similar training examples. We 017 empirically evaluate the case-based abductive 018 framework on downstream commonsense and 019 scientific reasoning tasks. Our experiments 020 demonstrate that ETNA can be effectively in-021 tegrated with sparse and dense encoding mech-022 anisms or downstream transformers, achiev-023 ing strong performance when compared to ex-024 isting explainable approaches. Moreover, we 025 study the impact of the retrieve - reuse - revise 026 paradigm on explainability and semantic drift, 027 showing that it boosts the quality of the con-028 structed explanations, resulting in improved 029 downstream inference performance. 030
Exploring the Wasserstein metric for survival analysis
Margaux Luck
Heloise Cardinal
Andrea Lodi
Machine Learning for Combinatorial Optimization: a Methodological Tour d'Horizon
This paper surveys the recent attempts, both from the machine learning and operations research communities, at leveraging machine learning t… (see more)o solve combinatorial optimization problems. Given the hard nature of these problems, state-of-the-art algorithms rely on handcrafted heuristics for making decisions that are otherwise too expensive to compute or mathematically not well defined. Thus, machine learning looks like a natural candidate to make such decisions in a more principled and optimized way. We advocate for pushing further the integration of machine learning and combinatorial optimization and detail a methodology to do so. A main point of the paper is seeing generic optimization problems as data points and inquiring what is the relevant distribution of problems to use for learning on a given task.
Multimodal Audio-textual Architecture for Robust Spoken Language Understanding
Yongqiang Wang
Christian Fue-730
Anuj Kumar
Baiyang Liu
Edwin Simonnet
Sahar Ghannay
Nathalie Camelin
Tandem spoken language understanding 001 (SLU) systems suffer from the so-called 002 automatic speech recognition (ASR) error 003 propagatio… (see more)n problem. Additionally, as the 004 ASR is not optimized to extract semantics, but 005 solely the linguistic content, relevant semantic 006 cues might be left out of its transcripts. In 007 this work, we propose a multimodal language 008 understanding (MLU) architecture to mitigate 009 these problems. Our solution is based on 010 two compact unidirectional long short-term 011 memory (LSTM) models that encode speech 012 and text information. A fusion layer is also 013 used to fuse audio and text embeddings. 014 Two fusion strategies are explored: a simple 015 concatenation of these embeddings and a 016 cross-modal attention mechanism that learns 017 the contribution of each modality. The first 018 approach showed to be the optimal solution 019 to robustly extract semantic information from 020 audio-textual data. We found that attention 021 is less effective at testing time when the text 022 modality is corrupted. Our model is evaluated 023 on three SLU datasets and robustness is tested 024 using ASR outputs from three off-the-shelf 025 ASR engines. Results show that the proposed 026 approach effectively mitigates the ASR error 027 propagation problem for all datasets. 028
Optimization of Artificial Neural Network Hyperparameters For Processing Retrospective Information
A. Rogachev
F. Scholle
I. L. Kashirin
M. Demchenko
. Justification of the selection of the architecture and hyperparameters of artificial neural networks (ANN), focused on solving various cla… (see more)sses of applied problems, is a scientific and methodological problem. Optimizing the selection of ANN hyperparameters allows you to improve the quality and speed of ANN training. Various methods of optimizing the selection of ANN hyper-parameters are known – the use of evolutionary calculations, genetic algorithms, etc., but they require the use of additional software. To optimize the process of selecting ANN hyperparameters, Google Research has developed the KerasTuner software tool. It is a platform for automated search of a set of optimal combinations of hyperparameters. In Kerastuner, you can use various methods - random search, Bayesian optimization, or Hyperband. In the numerical experiments conducted by the author, 14 hyperparameters were varied, including the number of blocks of convolutional layers and the filters forming them, the type of activation function, the parameters of the "dropout" layers, and others. The studied tools demonstrated high efficiency while simultaneously varying more than a dozen optimized parameters of the convolutional network. The calculation time on the Colaboratory platform for the various combined ANN architectures studied, including recurrent RNN networks, was several hours, even with the use of GPU graphics accelerators. For ANN, focused on the processing and recognition of retrospective information, an increase in the quality of recognition was achieved to 80 ... 95%.
Seeing things or seeing scenes: Investigating the capabilities of V&L models to align scene descriptions to images
M. D. Anderson
Erich W Graf
James H Elder
Peter Anderson
Xiaodong He
Chris Buehler
Mark Teney
Stephen Johnson
Gould Lei
Emily M. Bender
Timnit Gebru
Angelina McMillan-575
Alexander Koller. 2020
Climb-582
Yonatan Bisk
Ari Holtzman
Jesse Thomason
Angeliki Lazaridou … (see 32 more)
Jonathan May
Aleksandr
Thomas Unterthiner
Mostafa Dehghani
Georg Minderer
Sylvain Heigold
Jakob Gelly
Uszkoreit Neil
Houlsby. 2020
An
Lisa Anne Hendricks
Gabriel Ilharco
Rowan Zellers
Ali Farhadi
John M. Henderson
Contextual
Thomas L. Griffiths. 2021
Are Convolutional
Neu-827
Melissa L.-H. Võ
Jeremy M. Wolfe
Differen-830
Jianfeng Wang
Xiaowei Hu
Xiu-834 Pengchuan Zhang
Roy Schwartz
Bolei Zhou
Àgata Lapedriza
Jianxiong Xiao
Hang Zhao
Xavier Puig
Sanja Fidler
Images can be described in terms of the objects 001 they contain, or in terms of the types of scene 002 or place that they instantiate. In t… (see more)his paper we 003 address to what extent pretrained Vision and 004 Language models can learn to align descrip-005 tions of both types with images. We com-006 pare 3 state-of-the-art models, VisualBERT, 007 LXMERT and CLIP. We find that (i) V&L 008 models are susceptible to stylistic biases ac-009 quired during pretraining; (ii) only CLIP per-010 forms consistently well on both object-and 011 scene-level descriptions. A follow-up ablation 012 study shows that CLIP uses object-level infor-013 mation in the visual modality to align with 014 scene-level textual descriptions
A Simple and Effective Model for Multi-Hop Question Generation
Jimmy Lei Ba
Jamie Ryan Kiros
Geoffrey E Hin-602
Peter W. Battaglia
Jessica Blake
Chandler Hamrick
Vic-613 tor Bapst
Alvaro Sanchez
Vinicius Zambaldi
M. Malinowski
Andrea Tacchetti
David Raposo
Tom B. Brown
Benjamin Mann
Nick Ryder
Melanie Subbiah
Jared Kaplan
Prafulla Dhariwal
Arvind Neelakantan
Pranav Shyam … (see 72 more)
Girish Sastry
William L. Hamilton
Clutrr
Nitish Srivastava
Geoffrey Hinton
Alex Krizhevsky
Ilya Sutskever
Ruslan Salakhutdinov. 2014
Gabriel Stanovsky
Julian Michael
Luke Zettlemoyer
Dan Su
Yan Xu
Wenliang Dai
Ziwei Ji
Tiezheng Yu
Minghao Tu
Kevin Huang
Guangtao Wang
Jing Huang
Ashish Vaswani
Noam M. Shazeer
Niki Parmar
Jakob Uszkoreit
Llion Jones
Aidan N. Gomez
Łukasz Kaiser
Illia Polosukhin. 2017
Attention
Petar Veliˇckovi´c
Guillem Cucurull
Arantxa Casanova
Adriana Romero
Pietro Lio’
Johannes Welbl
Pontus Stenetorp
Yonghui Wu
Mike Schuster
Quoc Zhifeng Chen
Mohammad Le
Wolfgang Norouzi
Macherey
M. Krikun
Yuan Cao
Qin Gao
William W. Cohen
Jianxing Yu
Xiaojun Quan
Qinliang Su
Jian Yin
Yuyu Zhang
Hanjun Dai
Zornitsa Kozareva
Cheng Zhao
Chenyan Xiong
Corby Rosset
Xia
Paul Song
Bennett Saurabh
Tiwary
Yao Zhao
Xiaochuan Ni
Yuanyuan Ding
Qingyu Zhou
Nan Yang
Furu Wei
Chuanqi Tan
Previous research on automated question gen-001 eration has almost exclusively focused on gen-002 erating factoid questions whose answers ca… (see more)n 003 be extracted from a single document. How-004 ever, there is an increasing interest in develop-005 ing systems that are capable of more complex 006 multi-hop question generation (QG), where an-007 swering the question requires reasoning over 008 multiple documents. In this work, we pro-009 pose a simple and effective approach based on 010 the transformer model for multi-hop QG. Our 011 approach consists of specialized input repre-012 sentations, a supporting sentence classification 013 objective, and training data weighting. Prior 014 work on multi-hop QG considers the simpli-015 fied setting of shorter documents and also ad-016 vocates the use of entity-based graph struc-017 tures as essential ingredients in model design. 018 On the contrary, we showcase that our model 019 can scale to the challenging setting of longer 020 documents as input, does not rely on graph 021 structures, and substantially outperforms the 022 state-of-the-art approaches as measured by au-023 tomated metrics and human evaluation. 024