Publications

Tensor Networks for Probabilistic Sequence Modeling
Tensor networks are a powerful modeling framework developed for computational many-body physics, which have only recently been applied withi… (voir plus)n machine learning. In this work we utilize a uniform matrix product state (u-MPS) model for probabilistic modeling of sequence data. We first show that u-MPS enable sequence-level parallelism, with length-n sequences able to be evaluated in depth O(log n). We then introduce a novel generative algorithm giving trained u-MPS the ability to efficiently sample from a wide variety of conditional distributions, each one defined by a regular expression. Special cases of this algorithm correspond to autoregressive and fill-in-the-blank sampling, but more complex regular expressions permit the generation of richly structured data in a manner that has no direct analogue in neural generative models. Experiments on sequence modeling with synthetic and real text data show u-MPS outperforming a variety of baselines and effectively generalizing their predictions in the presence of limited data.
A Theoretical Analysis of Catastrophic Forgetting through the NTK Overlap Matrix
Thang Doan
Mehdi Bennani
Pierre Alquier
Continual learning (CL) is a setting in which an agent has to learn from an incoming stream of data during its entire lifetime. Although maj… (voir plus)or advances have been made in the field, one recurring problem which remains unsolved is that of Catastrophic Forgetting (CF). While the issue has been extensively studied empirically, little attention has been paid from a theoretical angle. In this paper, we show that the impact of CF increases as two tasks increasingly align. We introduce a measure of task similarity called the NTK overlap matrix which is at the core of CF. We analyze common projected gradient algorithms and demonstrate how they mitigate forgetting. Then, we propose a variant of Orthogonal Gradient Descent (OGD) which leverages structure of the data through Principal Component Analysis (PCA). Experiments support our theoretical findings and show how our method can help reduce CF on classical CL datasets.
[Strengthening the culture of public health surveillance and population health monitoring].
Arnaud Chiolero
David L Buckeridge
St'ephane Cullati
Public health surveillance is the systematic and ongoing collection, analysis and interpretation of data to produce information useful for d… (voir plus)ecision-making. With the development of data science, surveillance methods are evolving through access to big data. More data does not automatically mean more information. For example, the massive amounts of data on Covid-19 was not easily transformed in useful information for decision-making. Further, data scientists have often difficulties to make their analyses useful for decision-making. For the implementation of evidence-based and data-driven public health practice, the culture of public health surveillance and population health monitoring needs to be strengthened.
Price discounting as a hidden risk factor of energy drink consumption
Hiroshi Mamiya
Erica E. M. Moodie
Alexandra M. Schmidt
Yu Ma
David L. Buckeridge
Global consumption of caffeinated energy drinks (CED) has been increasing dramatically despite increasing evidence of their adverse health e… (voir plus)ffects. Temporary price discounting is a rarely investigated but potentially powerful food marketing tactic influencing purchasing of CED. Using grocery transaction records generated by food stores in Montreal, we investigated the association between price discounting and purchasing of CED across socio-economic status operationalized by education and income levels in store neighbourhood. The outcome, log-transformed weekly store-level sales of CED, was modelled as a function of store-level percent price discounting, store- and neighbourhood-level confounders, and an interaction term between discounting and each of tertile education and income in store neighbourhood. The model was separately fit to transactions from supermarkets, pharmacies, supercentres, and convenience stores. There were 18,743, 12,437, 3965, and 49,533 weeks of CED sales from supermarkets, pharmacies, supercentres, and convenience stores, respectively. Percent price discounting was positively associated with log sales of CED for all store types, and the interaction between education and discounting was prominent in supercentres: −0.039 [95% confidence interval (CI): −0.051, −0.028] and −0.039 [95% CI: −0.057, −0.021], for middle- and high-education neighbourhoods relative to low-education neighbourhoods, respectively. Relative to low-income areas, the associations of discounting and log CED sales in supercentres for neighbourhoods with middle- and high-income tertile were 0.022 [95% CI: 0.010, 0.033] and 0.015 (95% CI: −0.001, 0.031), respectively. Price discounting is an important driver of CED consumption and has a varying impact across community education and income.
Local Data Debiasing for Fairness Based on Generative Adversarial Training
Ulrich Matchi Aïvodji
François Bidet
Sébastien Gambs
Rosin Claude Ngueveu
The widespread use of automated decision processes in many areas of our society raises serious ethical issues with respect to the fairness o… (voir plus)f the process and the possible resulting discrimination. To solve this issue, we propose a novel adversarial training approach called GANSan for learning a sanitizer whose objective is to prevent the possibility of any discrimination (i.e., direct and indirect) based on a sensitive attribute by removing the attribute itself as well as the existing correlations with the remaining attributes. Our method GANSan is partially inspired by the powerful framework of generative adversarial networks (in particular Cycle-GANs), which offers a flexible way to learn a distribution empirically or to translate between two different distributions. In contrast to prior work, one of the strengths of our approach is that the sanitization is performed in the same space as the original data by only modifying the other attributes as little as possible, thus preserving the interpretability of the sanitized data. Consequently, once the sanitizer is trained, it can be applied to new data locally by an individual on their profile before releasing it. Finally, experiments on real datasets demonstrate the effectiveness of the approach as well as the achievable trade-off between fairness and utility.
Continuing professional education of Iranian healthcare professionals in shared decision-making: lessons learned
S. A. Rahimi
Charo Rodriguez
Jordie Croteau
Alireza Sadeghpour
Amir-Mohammad Navali
France Légaré
Staying Ahead of the Epidemiologic Curve: Evaluation of the British Columbia Asthma Prediction System (BCAPS) During the Unprecedented 2018 Wildfire Season
Sarah B. Henderson
Kathryn T. Morrison
Kathleen E. McLean
Yue Ding
Jiayun Yao
Gavin Shaddick
David L Buckeridge
Pretraining Reward-Free Representations for Data-Efficient Reinforcement Learning
Parallel inference of hierarchical latent dynamics in two-photon calcium imaging of neuronal populations
Luke Y. Prince
Colleen J. Gillon
Blake A. Richards
Dynamic latent variable modelling has provided a powerful tool for understanding how populations of neurons compute. For spiking data, such … (voir plus)latent variable modelling can treat the data as a set of point-processes, due to the fact that spiking dynamics occur on a much faster timescale than the computational dynamics being inferred. In contrast, for other experimental techniques, the slow dynamics governing the observed data are similar in timescale to the computational dynamics that researchers want to infer. An example of this is in calcium imaging data, where calcium dynamics can have timescales on the order of hundreds of milliseconds. As such, the successful application of dynamic latent variable modelling to modalities like calcium imaging data will rest on the ability to disentangle the deeper- and shallower-level dynamical systems’ contributions to the data. To-date, no techniques have been developed to directly achieve this. Here we solve this problem by extending recent advances using sequential variational autoencoders for dynamic latent variable modelling of neural data. Our system VaLPACa (Variational Ladders for Parallel Autoencoding of Calcium imaging data) solves the problem of disentangling deeper- and shallower-level dynamics by incorporating a ladder architecture that can infer a hierarchy of dynamical systems. Using some built-in inductive biases for calcium dynamics, we show that we can disentangle calcium flux from the underlying dynamics of neural computation. First, we demonstrate with synthetic calcium data that we can correctly disentangle an underlying Lorenz attractor from calcium dynamics. Next, we show that we can infer appropriate rotational dynamics in spiking data from macaque motor cortex after it has been converted into calcium fluorescence data via a calcium dynamics model. Finally, we show that our method applied to real calcium imaging data from primary visual cortex in mice allows us to infer latent factors that carry salient sensory information about unexpected stimuli. These results demonstrate that variational ladder autoencoders are a promising approach for inferring hierarchical dynamics in experimental settings where the measured variable has its own slow dynamics, such as calcium imaging data. Our new, open-source tool thereby provides the neuroscience community with the ability to apply dynamic latent variable modelling to a wider array of data modalities.
Training a First-Order Theorem Prover from Synthetic Data
Vlad Firoiu
Eser Aygün
Laurent Orseau
Lei Zhang
Shibl Mourad
Comment on Starke et al.: “Computing schizophrenia: ethical challenges for machine learning in psychiatry”: From machine learning to student learning: pedagogical challenges for psychiatry – Corrigendum
Christophe Gauld
Jean‐Arthur Micoulaud‐Franchi
Functional specialization within the inferior parietal lobes across cognitive domains
Ole Numssen
Gesa Hartwigsen
The inferior parietal lobe (IPL) is a key neural substrate underlying diverse mental processes, from basic attention to language and social … (voir plus)cognition, that define human interactions. Its putative domain-global role appears to tie into poorly understood differences between cognitive domains in both hemispheres. Across attentional, semantic, and social cognitive tasks, our study explored functional specialization within the IPL. The task specificity of IPL subregion activity was substantiated by distinct predictive signatures identified by multivariate pattern-learning algorithms. Moreover, the left and right IPL exerted domain-specific modulation of effective connectivity among their subregions. Task-evoked functional interactions of the anterior and posterior IPL subregions involved recruitment of distributed cortical partners. While anterior IPL subregions were engaged in strongly lateralized coupling links, both posterior subregions showed more symmetric coupling patterns across hemispheres. Our collective results shed light on how under-appreciated hemispheric specialization in the IPL supports some of the most distinctive human mental capacities.