Peu importe la taille : démocratiser la découverte de protéines avec l'IA
Des chercheurs de Mila ont créé un puissant modèle de langage protéique à source ouverte plus compact et efficace afin de démocratiser la découverte de protéines.
La prochaine cohorte de notre programme, conçu pour fournir aux participant·e·s une compréhension fondamentale des technologies de l'IA, se déroulera à Ottawa les 28 et 29 novembre.
Nous utilisons des témoins pour analyser le trafic et l’utilisation de notre site web, afin de personnaliser votre expérience. Vous pouvez désactiver ces technologies à tout moment, mais cela peut restreindre certaines fonctionnalités du site. Consultez notre Politique de protection de la vie privée pour en savoir plus.
Paramètre des cookies
Vous pouvez activer et désactiver les types de cookies que vous souhaitez accepter. Cependant certains choix que vous ferez pourraient affecter les services proposés sur nos sites (ex : suggestions, annonces personnalisées, etc.).
Cookies essentiels
Ces cookies sont nécessaires au fonctionnement du site et ne peuvent être désactivés. (Toujours actif)
Cookies analyse
Acceptez-vous l'utilisation de cookies pour mesurer l'audience de nos sites ?
Multimedia Player
Acceptez-vous l'utilisation de cookies pour afficher et vous permettre de regarder les contenus vidéo hébergés par nos partenaires (YouTube, etc.) ?
Publications
Continuous cutting plane algorithms in integer programming
Curriculum frameworks and educational programs in artificial intelligence for medical students, residents, and practicing physicians: a scoping review protocol.
OBJECTIVE
The aim of this scoping review is to synthesize knowledge from the literature on curriculum frameworks and current educational pro… (voir plus)grams that focus on the teaching and learning of artificial intelligence (AI) for medical students, residents, and practicing physicians.
INTRODUCTION
To advance the implementation of AI in clinical practice, physicians need to have a better understanding of AI and how to use it within clinical practice. Consequently, medical education must introduce AI topics and concepts into the curriculum. Curriculum frameworks are educational road maps to teaching and learning. Therefore, any existing AI curriculum frameworks must be reviewed and, if none exist, such a framework must be developed.
INCLUSION CRITERIA
This review will include articles that describe curriculum frameworks for teaching and learning AI in medicine, irrespective of country. All types of articles and study designs will be included, except conference abstracts and protocols.
METHODS
This review will follow the JBI methodology for scoping reviews. Keywords will first be identified from relevant articles. Another search will then be conducted using the identified keywords and index terms. The following databases will be searched: MEDLINE (Ovid), Embase (Ovid), Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL (EBSCOhost), and Scopus. Gray literature will also be searched. Articles will be limited to the English and French languages, commencing from the year 2000. The reference lists of all included articles will be screened for additional articles. Data will then be extracted from included articles and the results will be presented in a table.
It is critical to measure and mitigate fairness-related harms caused by AI text generation systems, including stereotyping and demeaning har… (voir plus)ms. To that end, we introduce FairPrism, a dataset of 5,000 examples of AI-generated English text with detailed human annotations covering a diverse set of harms relating to gender and sexuality. FairPrism aims to address several limitations of existing datasets for measuring and mitigating fairness-related harms, including improved transparency, clearer specification of dataset coverage, and accounting for annotator disagreement and harms that are context-dependent. FairPrism’s annotations include the extent of stereotyping and demeaning harms, the demographic groups targeted, and appropriateness for different applications. The annotations also include specific harms that occur in interactive contexts and harms that raise normative concerns when the “speaker” is an AI system. Due to its precision and granularity, FairPrism can be used to diagnose (1) the types of fairness-related harms that AI text generation systems cause, and (2) the potential limitations of mitigation methods, both of which we illustrate through case studies. Finally, the process we followed to develop FairPrism offers a recipe for building improved datasets for measuring and mitigating harms caused by AI systems.
2023-07-01
Proceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers) (publié)
Intrusion detection systems (IDSs) are crucial in the security monitoring for the smart grid with increasing machine-to-machine communicatio… (voir plus)ns and cyber threats thereafter. However, the multi-sourced, correlated, and heterogeneous smart grid data pose significant challenges to the accurate attack detection by IDSs. To improve the attack detection, this paper proposes Reinforcement Learning-based Adaptive Feature Boosting, which aims to leverage a series of AutoEncoders (AEs) to capture critical features from the multi-sourced smart grid data for the classification of normal, fault, and attack events. Multiple AEs are utilized to extract representative features from different feature sets that are automatically generated through a weighted feature sampling process; each AE-extracted feature set is then applied to build a Random Forest (RF) base classifier. In the feature sampling process, Deep Deterministic Policy Gradient (DDPG) is introduced to dynamically determine the feature sampling probability based on the classification accuracy. The critical features that improve the classification accuracy are assigned larger sampling probabilities and increasingly participate in the training of next AE. The presence of critical features is increased in the event classification over the multi-sourced smart grid data. Considering potential different alarms among base classifiers, an ensemble classifier is further built to distinguish normal, fault, and attack events. Our proposed approach is evaluated on the two realistic datasets collected from Hardware-In-the-Loop (HIL) and WUSTIL-IIOT-2021 security testbeds, respectively. The evaluation on the HIL security dataset shows that our proposed approach achieves the classification accuracy with 97.28%, an effective 5.5% increase over the vanilla Adaptive Feature Boosting. Moreover, the proposed approach not only accurately and stably selects critical features on the WUSTIL-IIOT-2021 dataset based on the significant difference of feature sampling probabilities between critical and uncritical features, i.e., the probabilities greater than 0.08 and less than 0.01, but also outperforms the other best-performing approaches with the increasing Matthew Correlation Coefficient (MCC) of 8.03%.
Deep learning-based algorithms have been very successful in skeleton-based human activity recognition. Skeleton data contains 2-D or 3-D coo… (voir plus)rdinates of human body joints. The main focus of most of the existing skeleton-based activity recognition methods is on designing new deep architectures to learn discriminative features, where all body joints are considered equally important in recognition. However, the importance of joints varies as an activity proceeds within a video and across different activities. In this work, we hypothesize that selecting relevant joints, prior to recognition, can enhance performance of the existing deep learning-based recognition models. We propose a spatial hard attention finding method that aims to remove the uninformative and/or misleading joints at each frame. We formulate the joint selection problem as a Markov decision process and employ deep reinforcement learning to train the proposed spatial-attention-aware agent. No extra labels are needed for the agent’s training. The agent takes a sequence of features extracted from skeleton video as input and outputs a sequence of probabilities for joints. The proposed method can be considered as a general framework that can be integrated with the existing skeleton-based activity recognition methods for performance improvement purposes. We obtain very competitive activity recognition results on three commonly used human activity recognition datasets.
2023-07-01
IEEE Transactions on Systems, Man, and Cybernetics: Systems (publié)
Graph Neural Networks (GNNs) have emerged as a powerful tool for data-driven learning on various graph domains. They are usually based on a … (voir plus)message-passing mechanism and have gained increasing popularity for their intuitive formulation, which is closely linked to the Weisfeiler-Lehman (WL) test for graph isomorphism to which they have been proven equivalent in terms of expressive power. In this work, we establish new generalization properties and fundamental limits of GNNs in the context of learning so-called identity effects, i.e., the task of determining whether an object is composed of two identical components or not. Our study is motivated by the need to understand the capabilities of GNNs when performing simple cognitive tasks, with potential applications in computational linguistics and chemistry. We analyze two case studies: (i) two-letters words, for which we show that GNNs trained via stochastic gradient descent are unable to generalize to unseen letters when utilizing orthogonal encodings like one-hot representations; (ii) dicyclic graphs, i.e., graphs composed of two cycles, for which we present positive existence results leveraging the connection between GNNs and the WL test. Our theoretical analysis is supported by an extensive numerical study.
Abstract Motivation Accurately assessing contacts between DNA fragments inside the nucleus with Hi-C experiment is crucial for understanding… (voir plus) the role of 3D genome organization in gene regulation. This challenging task is due in part to the high sequencing depth of Hi-C libraries required to support high-resolution analyses. Most existing Hi-C data are collected with limited sequencing coverage, leading to poor chromatin interaction frequency estimation. Current computational approaches to enhance Hi-C signals focus on the analysis of individual Hi-C datasets of interest, without taking advantage of the facts that (i) several hundred Hi-C contact maps are publicly available and (ii) the vast majority of local spatial organizations are conserved across multiple cell types. Results Here, we present RefHiC-SR, an attention-based deep learning framework that uses a reference panel of Hi-C datasets to facilitate the enhancement of Hi-C data resolution of a given study sample. We compare RefHiC-SR against tools that do not use reference samples and find that RefHiC-SR outperforms other programs across different cell types, and sequencing depths. It also enables high-accuracy mapping of structures such as loops and topologically associating domains. Availability and implementation https://github.com/BlanchetteLab/RefHiC.