Publications

A neuronal least-action principle for real-time learning in cortical circuits
Walter Senn
Dominik Dold
Akos F. Kungl
Benjamin Ellenberger
Jakob Jordan
João Sacramento
Mihai A. Petrovici
One of the most fundamental laws of physics is the principle of least action. Motivated by its predictive power, we introduce a neuronal lea… (see more)st-action principle for cortical processing of sensory streams to produce appropriate behavioural outputs in real time. The principle postulates that the voltage dynamics of cortical pyramidal neurons prospectively minimize the local somato-dendritic mismatch error within individual neurons. For motor output neurons, it implies minimizing an instantaneous behavioural error. For deep network neurons, it implies a prospective firing to overcome integration delays and correct for possible output errors right in time. The neuron-specific errors are extracted in the apical dendrites of pyramidal neurons through a cortical microcircuit that tries to explain away the feedback from the periphery, and correct the trajectory on the fly. Any motor output is in a moving equilibrium with the sensory inputs and the motor feedback during the whole sensory-motor trajectory. Ongoing synaptic plasticity reduces the somato-dendritic mismatch error within each cortical neuron and performs gradient descent on the output cost at any moment in time. The neuronal least-action principle offers an axiomatic framework to derive local neuronal and synaptic dynamics for global real-time computation and learning in the brain and in physical substrates in general.
Protein Language Models: Is Scaling Necessary?
Quentin Fournier
Robert M. Vernon
Almer van der Sloot
Benjamin Schulz
Christopher James Langmead
A Toolbox for Surfacing Health Equity Harms and Biases in Large Language Models
Stephen R. Pfohl
Heather Cole-Lewis
Rory A Sayres
Darlene Neal
Mercy Nyamewaa Asiedu
Awa Dieng
Nenad Tomašev
Qazi Mamunur Rashid
Shekoofeh Azizi
Liam G. McCoy
L. A. Celi
Yun Liu
Mike Schaekermann
Alanna Walton
Alicia Parrish
Chirag Nagpal
Preeti Singh
Akeiylah Dewitt
P. A. Mansfield … (see 10 more)
Sushant Prakash
Katherine Heller
Alan Karthikesalingam
Christopher Semturs
Joelle Barral
Greg C. Corrado
Yossi Matias
Jamila Smith-Loud
Ivor Horn
Karan Singhal
What Are They Doing? Joint Audio-Speech Co-Reasoning
Yingzhi Wang
Pooneh Mousavi
Artem Ploujnikov
AI content detection in the emerging information ecosystem: new obligations for media and tech companies
Alistair Knott
Dino Pedreschi
Toshiya Jitsuzumi
Susan Leavy
D. Eyers
Tapabrata Chakraborti
Andrew Trotman
Sundar Sundareswaran
Ricardo Baeza-Yates
Przemyslaw Biecek
Adrian Weller
Paul D. Teal
Subhadip Basu
Mehmet Haklidir
Virginia Morini
Stuart Russell
ToxiSight: Insights Towards Detected Chat Toxicity
Zachary Yang
Domenico Tullo
We present a comprehensive explainability dashboard designed for in-game chat toxicity. This dashboard integrates various existing explainab… (see more)le AI (XAI) techniques, including token importance analysis, model output visualization, and attribution to the training dataset. It also provides insights through the closest positive and negative examples, facilitating a deeper understanding and potential correction of the training data. Additionally, the dashboard includes word sense analysis—particularly useful for new moderators—and offers free-text explanations for both positive and negative predictions. This multi-faceted approach enhances the interpretability and transparency of toxicity detection models.
ChainBuddy: An AI Agent System for Generating LLM Pipelines
Jingyue Zhang
Development of small, cost‐efficient scintillating fiber detectors for automated synthesis of positron emission tomography radiopharmaceuticals
Hailey Ahn
Liam Carroll
Robert Hopewell
I-Huang Tsai
Dean Jolly
Gassan Massarweh
Dynamic HumTrans: Humming Transcription Using CNNs and Dynamic Programming
Shubham Gupta
Isaac Neri Gomez-Sarmiento
Faez Amjed Mezdari
Enhancing Logical Reasoning in Large Language Models through Graph-based Synthetic Data
Jiaming Zhou
Abbas Ghaddar
Ge Zhang
Liheng Ma
Yaochen Hu
Soumyasundar Pal
Bin Wang
Yingxue Zhang
Jianye Hao
Explaining Network Decision Provides Insights on the Causal Interaction Between Brain Regions in a Motor Imagery Task
Davide Borra
Multi-modal Decoding of Reach-to-Grasping from EEG and EMG via Neural Networks
Davide Borra
Matteo Fraternali
Elisa Magosso