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Publications
Mortality trends and lengths of stay among hospitalized COVID-19 patients in Ontario and Quebec (Canada): a population-based cohort study of the first three epidemic waves
Background: Epidemic waves of COVID-19 strained hospital resources. We describe temporal trends in mortality risk and length of stay in inte… (voir plus)nsive cares units (ICUs) among COVID-19 patients hospitalized through the first three epidemic waves in Canada. Methods: We used population-based provincial hospitalization data from Ontario and Québec to examine mortality risk and lengths of ICU stay. For each province, adjusted estimates were obtained using marginal standardization of logistic regression models, adjusting for patient-level characteristics and hospital-level determinants. Results: Using all hospitalizations from Ontario (N=26,541) and Québec (N=23,857), we found that unadjusted in-hospital mortality risks peaked at 31% in the first wave and was lowest at the end of the third wave at 6-7%. This general trend remained after controlling for confounders. The odds of in-hospital mortality in the highest hospital occupancy quintile was 1.2 (95%CI: 1.0-1.4; Ontario) and 1.6 (95%CI: 1.3-1.9; Québec) times that of the lowest quintile. Variants of concerns were associated with an increased in-hospital mortality. Length of ICU stay decreased over time from a mean of 16 days (SD=18) to 15 days (SD=15) in the third wave but were consistently higher in Ontario than Québec by 3-6 days. Conclusion: In-hospital mortality risks and lengths of ICU stay declined over time in both provinces, despite changing patient demographics, suggesting that new therapeutics and treatment, as well as improved clinical protocols, could have contributed to this reduction. Continuous population-based monitoring of patient outcomes in an evolving epidemic is necessary for health system preparedness and response.
In modern days, social media platforms provide accessible channels for the inter-action and immediate reflection of the most important event… (voir plus)s happening around the world. In this paper, we, firstly, present a curated set of datasets whose origin stem from the Twitter’s Information Operations efforts. More notably, these accounts, which have been already suspended, provide a notion of how state-backed human trolls operate.Secondly, we present detailed analyses of how these behaviours vary over time,and motivate its use and abstraction in the context of deep representation learning:for instance, to learn and, potentially track, troll behaviour. We present baselinesf or such tasks and highlight the differences there may exist within the literature.Finally, we utilize the representations learned for behaviour prediction to classify trolls from"real"users, using a sample of non-suspended active accounts.
2021-12-07
LatinX in AI at Neural Information Processing Systems Conference 2021 (publié)
Patient health records and whole viral genomes from an early SARS-CoV-2 outbreak in a Quebec hospital reveal features associated with favorable outcomes
Adapting to the COVID‐19 pandemic in cohort studies: Validation of online assessments of cognition and neuropsychiatric symptoms in an aging population
The occurrence of the COVID‐19 pandemic has had a significant impact on cohort studies, particularly those whose subjects are at higher ri… (voir plus)sk of developing complications from the virus. As such, assessment methods must be adapted to minimize COVID‐19 exposure risk. The TRIAD (Translational Biomarkers of Aging and Dementia) cohort assessed N=292 individuals during initial COVID‐19 lockdown measures by telephone interview to rate cognition, neuropsychiatric symptoms, and impact of the pandemic. To increase speed and efficiency of data collection, we aim to follow these individuals by means of online survey. Here, we present a validation of our online assessment tools by comparing data obtained through both methods (phone interview and online survey) in the same subjects.
We present a generative adversarial method that uses deep learning to identify network load traffic conditions in which network optimization… (voir plus) algorithms under-perform other known algorithms: the Deep Convolutional Failure Generator (DCFG). The spatial distribution of network load presents challenges for network operators for tasks such as load balancing, in which a network optimizer attempts to maintain high quality communication while at the same time abiding capacity constraints. Testing a network optimizer for all possible load distributions is challenging if not impossible. We propose a novel method that searches for load situations where a target network optimization method underperforms baseline, which are key test cases that can be used for future refinement and performance optimization. By modeling a realistic network simulator's quality assessments with a deep network and, in parallel, optimizing a load generation network, our method efficiently searches the high dimensional space of load patterns and reliably finds cases in which a target network optimization method under-performs a baseline by a significant margin.
In today’s age of (mis)information, many people utilize various social media platforms in an attempt to shape public opinion on several im… (voir plus)portant issues, including elections and the COVID-19 pandemic. These two topics have recently become intertwined given the importance of complying with public health measures related to COVID-19 and politicians’ management of the pandemic. Motivated by this, we study the partisan polarization of COVID-19 discussions on social media. We propose and utilize a novel measure of partisan polarization to analyze more than 380 million posts from Twitter and Parler around the 2020 US presidential election. We find strong correlation between peaks in polarization and polarizing events, such as the January 6th Capitol Hill riot. We further classify each post into key COVID-19 issues of lockdown, masks, vaccines, as well as miscellaneous, to investigate both the volume and polarization on these topics and how they vary through time. Parler includes more negative discussions around lockdown and masks, as expected, but not much around vaccines. We also observe more balanced discussions on Twitter and a general disconnect between the discussions on Parler and Twitter.
2021-12-01
2021 International Conference on Data Mining Workshops (ICDMW) (publié)
While the global COVID‐19 pandemic has hindered many human research operations, it has allowed for the investigation of novel scientific q… (voir plus)uestions. Particularly, the effects of the pandemic and its resulting social isolation on elderly individuals and their association with Alzheimer’s disease biomarkers remains a broad and open question. Here, we sought to investigate whether knowledge of COVID‐19, pandemic‐related distress, and changes in sleep quality were associated with in vivo tau deposition in an AD‐enriched cohort.
