Peu importe la taille : démocratiser la découverte de protéines avec l'IA
Des chercheurs de Mila ont créé un puissant modèle de langage protéique à source ouverte plus compact et efficace afin de démocratiser la découverte de protéines.
La prochaine cohorte de notre programme, conçu pour fournir aux participant·e·s une compréhension fondamentale des technologies de l'IA, se déroulera à Ottawa les 28 et 29 novembre.
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Spectral methods of moments provide a powerful tool for learning the parameters of latent variable models. Despite their theoretical appeal,… (voir plus) the applicability of these methods to real data is still limited due to a lack of robustness to model misspecification. In this paper we present a hierarchical approach to methods of moments to circumvent such limitations. Our method is based on replacing the tensor decomposition step used in previous algorithms with approximate joint diagonalization. Experiments on topic modeling show that our method outperforms previous tensor decomposition methods in terms of speed and model quality.
We consider the problem of estimating multiple related functions computed by weighted automata~(WFA). We first present a natural notion of r… (voir plus)elatedness between WFAs by considering to which extent several WFAs can share a common underlying representation. We then introduce the model of vector-valued WFA which conveniently helps us formalize this notion of relatedness. Finally, we propose a spectral learning algorithm for vector-valued WFAs to tackle the multitask learning problem. By jointly learning multiple tasks in the form of a vector-valued WFA, our algorithm enforces the discovery of a representation space shared between tasks. The benefits of the proposed multitask approach are theoretically motivated and showcased through experiments on both synthetic and real world datasets.
Many real world applications include information on both attributes of individual entities as well as relations between them, while there ex… (voir plus)ists an interplay between these attributes and relations. For example, in a typical social network, the similarity of individuals’ characteristics motivates them to form relations, a.k.a. social selection; whereas the characteristics of individuals may be affected by the characteristics of their relations, a.k.a. social influence. We can measure proclivity in networks by quantifying the correlation of nodal attributes and the structure [1]. Here, we are interested in a more fundamental study, to extend the basic statistics defined for graphs and draw parallels for the attributed graphs. More formally, an attributed graph is denoted by (A,X); where An×n is the adjacency matrix and encodes the relationships between the n nodes, and Xn×k is the attributes matrix –each row shows the feature vector of the corresponding node. Degree of a node encodes the number of its neighbors, computed as ki = ∑ j Aij . We can extend this notion to networks with binary attributes to the number of neighbors which share a particular attribute x, i.e. ki(x) = ∑ j Aijδ(Xj , x); where δ(Xj , x) = 1 iff node j has attribute x. Similar to the simple graphs, where the degree distribution is studied and showed to be heavy tail, here we can look at: 1) the degree distributions per attribute, 2) the joint probability distribution of any pair of attributes. Moreover, if we assume A(x1, x2) is the induced subgraph (or masked matrix of edges) with endpoints of values (x1, x2), i.e., A(x1, x2) = Aijδ(Xi, x1)δ(Xj , x2), then we can study and compare these distributions for the induced subgraph per each pair of attribute values. For example, Figure 1 shows the same general trend in the distribution of the original graph and the three possible induced subgraph.
Learning tasks such as those involving genomic data often poses a serious challenge: the number of input features can be orders of magnitude… (voir plus) larger than the number of training examples, making it difficult to avoid overfitting, even when using the known regularization techniques. We focus here on tasks in which the input is a description of the genetic variation specific to a patient, the single nucleotide polymorphisms (SNPs), yielding millions of ternary inputs. Improving the ability of deep learning to handle such datasets could have an important impact in precision medicine, where high-dimensional data regarding a particular patient is used to make predictions of interest. Even though the amount of data for such tasks is increasing, this mismatch between the number of examples and the number of inputs remains a concern. Naive implementations of classifier neural networks involve a huge number of free parameters in their first layer: each input feature is associated with as many parameters as there are hidden units. We propose a novel neural network parametrization which considerably reduces the number of free parameters. It is based on the idea that we can first learn or provide a distributed representation for each input feature (e.g. for each position in the genome where variations are observed), and then learn (with another neural network called the parameter prediction network) how to map a feature's distributed representation to the vector of parameters specific to that feature in the classifier neural network (the weights which link the value of the feature to each of the hidden units). We show experimentally on a population stratification task of interest to medical studies that the proposed approach can significantly reduce both the number of parameters and the error rate of the classifier.
In this paper, we derive a multisensor multi-Bernoulli (MS-MeMBer) filter for multitarget tracking. Measurements from multiple sensors are e… (voir plus)mployed by the proposed filter to update a set of tracks modeled as a multi-Bernoulli random finite set. An exact implementation of the MS-MeMBer update procedure is computationally intractable. We propose an efficient approximate implementation by using a greedy measurement partitioning mechanism. The proposed filter allows for Gaussian mixture or particle filter implementations. Numerical simulations conducted for both linear-Gaussian and nonlinear models highlight the improved accuracy of the MS-MeMBer filter and its reduced computational load with respect to the multisensor cardinalized probability hypothesis density filter and the iterated-corrector cardinality-balanced multi-Bernoulli filter especially for low probabilities of detection.
Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficie… (voir plus)ntly. Since its introduction, it has been one of the most used CPU and GPU mathematical compilers - especially in the machine learning community - and has shown steady performance improvements. Theano is being actively and continuously developed since 2008, multiple frameworks have been built on top of it and it has been used to produce many state-of-the-art machine learning models.
The present article is structured as follows. Section I provides an overview of the Theano software and its community. Section II presents the principal features of Theano and how to use them, and compares them with other similar projects. Section III focuses on recently-introduced functionalities and improvements. Section IV compares the performance of Theano against Torch7 and TensorFlow on several machine learning models. Section V discusses current limitations of Theano and potential ways of improving it.
Theano is a Python library that allows to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficie… (voir plus)ntly. Since its introduction, it has been one of the most used CPU and GPU mathematical compilers - especially in the machine learning community - and has shown steady performance improvements. Theano is being actively and continuously developed since 2008, multiple frameworks have been built on top of it and it has been used to produce many state-of-the-art machine learning models.
The present article is structured as follows. Section I provides an overview of the Theano software and its community. Section II presents the principal features of Theano and how to use them, and compares them with other similar projects. Section III focuses on recently-introduced functionalities and improvements. Section IV compares the performance of Theano against Torch7 and TensorFlow on several machine learning models. Section V discusses current limitations of Theano and potential ways of improving it.