Portrait de Henry Denny n'est pas disponible

Henry Denny

Alumni

Publications

Visual objects refine head direction coding
Dominique Siegenthaler
Henry Denny
Sofia Skromne Carrasco
Johanna Luise Mayer
Daniel Levenstein
Adrien Peyrache
Stuart Trenholm
Émilie Macé
Animals use visual objects to guide navigation-related behaviors. However, visual object-preferring areas have yet to be described in the mo… (voir plus)use brain, limiting our understanding of how visual objects affect spatial navigation system processing. Using functional ultrasound imaging, we identified brain areas that were preferentially activated by images of objects compared with their scrambled versions. Whereas visual cortex did not show a preference, areas associated with spatial navigation were preferentially activated by visual objects. Electrophysiological recordings in postsubiculum, the cortical head direction (HD) system hub, confirmed a preference for visual objects in both HD cells and fast-spiking interneurons. In freely moving animals, visual objects increased firing rates of HD cells aligned with a visual object but decreased activity in HD cells coding for other directions.
2025-09-10
Science (publié)
doi.org