Portrait of Guillaume Dumas

Guillaume Dumas

Associate Academic Member
Associate Professor, Université de Montréal, Department of Psychiatry and Addiction
Adjunct Professor, McGill University, Department of Psychiatry
Research Topics
Computational Biology
Computational Neuroscience
Deep Learning
Dynamical Systems
Machine Learning Theory
Medical Machine Learning
Reinforcement Learning
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Biography

Guillaume Dumas is an associate professor of computational psychiatry in the Faculty of Medicine, Université de Montréal, and principal investigator in the Precision Psychiatry and Social Physiology laboratory at the Centre hospitalier universitaire (CHU) Sainte-Justine Research Centre. He holds the IVADO professorship for AI in Mental Health, and the Fonds de recherche du Québec - Santé (FRQS) J1 in AI and Digital Health. In 2023, Dumas was recognized as a CIFAR Azrieli Global Scholar – Brain, Mind, and Consciousness program, and nominated as a Future Leader in Canadian Brain Research by the Brain Canada Foundation.

Dumas was previously a permanent researcher in neuroscience and computational biology at the Institut Pasteur (Paris). Before that, he was a postdoctoral fellow at the Center for Complex Systems and Brain Sciences (Florida Atlanta University). He holds an engineering degree in advanced engineering and computer science (École Centrale Paris), two MSc degrees (theoretical physics, Paris-Saclay University; cognitive science, ENS/EHESS/Paris 5), and a PhD in cognitive neuroscience (Sorbonne University).

The goal of his research is to cross-fertilize AI/ML, cognitive neuroscience and digital medicine through an interdisciplinary program with two main axes:

- AI/ML for Mental Health, which aims to create new algorithms to investigate the development of human cognitive architecture and deliver personalized medicine in neuropsychiatry using data from genomes to smartphones.

- Social Neuroscience for AI/ML, which translates basic brain research and dynamical systems formalism into neurocomputational and machine learning hybrid models (NeuroML) and machines with social learning abilities (Social NeuroAI & HMI).

Current Students

Saskia Helbling
Postdoctorate - Université de Montréal
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Nadine Mohamed
Master's Research - Université de Montréal
Rémy Ramadour
Independent visiting researcher - CHU Sainte Justine / Université de Montréal
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Mahta Ramezanian
Master's Research - Université de Montréal
Principal supervisor :
Irina Rish
Pascal Tikeng Notsawo
PhD - Université de Montréal
Principal supervisor :
Guillaume Rabusseau
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Publications

Persistent Instability in LLM's Personality Measurements: Effects of Scale, Reasoning, and Conversation History
Tommaso Tosato
Saskia Helbling
Yorguin-Jose Mantilla-Ramos
Mahmood Hegazy
Alberto Tosato
D. Lemay
Irina Rish
Guillaume Dumas
2025-08-05
ArXiv (preprint)
doi.org
arxiv.org
Posttraumatic Growth in Intensive Care Unit Health Care Professionals After COVID-19
Elie Azoulay
Laurent Argaud
Vincent Labbé
Guillaume Dumas
Fabrice Bruneel
Mercé Jourdain
Christophe Guitton
Amelie Seguin
Samir Jaber
David Schnell
Isabelle Vinatier
Fanny Ardisson
Michel Ramakers
Antoine Herault
Olivier Lesieur
Alain Cariou
Antoine Vieillard-Baron
Olivier Guisset
Frédéric Pochard
Michael Darmon … (see 1 more)
Nancy Kentish-Barnes
2025-07-31
JAMA Network Open (published)
doi.org
Parsing Autism Heterogeneity: Transcriptomic Subgrouping of Imaging-Derived Phenotypes in Autism.
Johanna Leyhausen
Caroline Gurr
Lisa M. Berg
Hanna Seelemeyer
Bassem Hermila
Tim Schäfer
Andreas Chiocchetti
Charlotte M. Pretzsch
Eva Loth
Beth Oakley
Jan K. Buitelaar
Christian Beckmann
Tony Charman
Thomas Bourgeron
Eli Barthome
Tobias Banaschewski
Jumana Ahmad
Sara Ambrosino
Bonnie Auyeung
Simon Baron-Cohen … (see 56 more)
Sarah Baumeister
Sven Bölte
Carsten Bours
Michael Brammer
Daniel Brandeis
Claudia Brogna
Yvette de Bruijn
Bhismadev Chakrabarti
Ineke Cornelissen
Daisy Crawley
Flavio Dell’Acqua
Guillaume Dumas
Sarah Durston
Christine Ecker
Jessica Faulkner
Vincent Frouin
Pilar Garcés
David Goyard
Lindsay Ham
Hannah Hayward
Joerg F. Hipp
Rosemary Holt
Mark Johnson
Emily J. H. Jones
Prantik Kundu
Meng-Chuan Lai
Xavier Liogier D’ardhuy
Michael V. Lombardo
David J. Lythgoe
René Mandl
Andre Marquand
Luke Mason
Maarten Mennes
Andreas Meyer-Lindenberg
Carolin Moessnang
Nico Bast
Larry O’Dwyer
Marianne Oldehinkel
Bob Oranje
Gahan Pandina
Antonio Persico
Barbara Ruggeri
Amber N. V. Ruigrok
Jessica Sabet
Roberto Sacco
Antonia San José Cáceres
Emily Simonoff
Will Spooren
Julian Tillmann
Roberto Toro
Heike Tost
Jack Waldman
Steve C. R. Williams
Caroline Wooldridge
Marcel P. Zwiers
Declan Murphy
2025-06-30
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging (published)
doi.org
Inter-brain Synchronization in the Alpha Band during Minimal Tactile Interaction
Chen Lam Loh
Leonardo Zapata-Fonseca
Mark M. James
Guillaume Dumas
Tom Froese
Recently the minimal requirements for inter-brain coupling have attracted attention. Moreover, researchers have found that brains can couple… (see more) not only when individuals are in the same space, but also during technologically mediated interactions. Here we investigate whether inter-brain synchronization occurs when both conditions of spatial isolation and minimal interaction are satisfied. In particular, we use a real-time interaction paradigm, the Perceptual Crossing Experiment where individuals must locate their partners in a minimal virtual space using tactile stimuli alone. We report novel findings that contribute to our understanding of inter-brain synchronization and the minimal conditions of social interaction in virtual spaces : 1)inter-brain synchronization is present in the Alpha band during online minimal interaction, 2)five behavioral patterns and three inter-brain patterns can be found in the PCE and 3)different behavioral patterns in the interaction environment recruited different inter-brain networks such that frontal-fronto-central synchrony occurs when people are further apart in space, interacting with a multitude of objects. These findings have important implications for the understanding of social interaction processes, such that inter-brain coupling can occur even without extensive communication channels.
2025-06-23
bioRxiv (preprint)
doi.org
Impact de l'antibiothérapie par Daptomycine dans le traitement des bactériémies à Enterococcus faecium en réanimation : l'étude rétrospective multicentrique ENTERODAPTO.
S. Herbel
Guillaume Dumas
L. Chantelot
J. Massol
Q. Moyon
J. Ricard
E. Azoulay
C. Hauw-Berlemont
E. Maury
T. Urbina
2025-05-31
Médecine et Maladies Infectieuses Formation (published)
doi.org
A systematic review of hyperscanning in clinical encounters
Lena Adel
Lisane Moses
Elisabeth Irvine
Kyle T Greenway
Guillaume Dumas
Michael Lifshitz
2025-05-31
Neuroscience and Biobehavioral Reviews (published)
doi.org
Response letter to “Confounding by indication and exposure misclassification may undermine corticosteroid effect estimates in ICU patients with alcohol-related hepatitis”
Guillaume Dumas
Maxime Gasperment
Hafid AIT-OUFELLA
2025-05-23
Annals of Intensive Care (published)
doi.org
Persistent signs of poisoning after massive drug ingestion: move the ultrasound probe to the stomach.
N. Lautrou-cabasson
H. Pirollet
C. Lombois
Guillaume Dumas
2025-05-14
Intensive Care Medicine (published)
doi.org
Proceedings of 1st Workshop on Advancing Artificial Intelligence through Theory of Mind
Mouad Abrini
Omri Abend
Dina M. Acklin
Henny Admoni
Gregor Aichinger
Nitay Alon
Zahra Ashktorab
Ashish Atreja
Moises Auron
Alexander Aufreiter
Raghav Awasthi
Soumya Banerjee
Joseph Barnby
Rhea Basappa
Severin Bergsmann
Djallel Bouneffouf
Patrick Callaghan
Marc Cavazza
Thierry Chaminade
Sonia Chernova … (see 88 more)
Mohamed Chetouan
Moumita Choudhury
Axel Cleeremans
J. Cywinski
Fabio Cuzzolin
Hokin Deng
N'yoma Diamond
C. D. Pasquasio
Guillaume Dumas
Max J. van Duijn
Mahapatra Dwarikanath
Qingying Gao
Ashok Goel
Rebecca R. Goldstein
Matthew C. Gombolay
Gabriel Enrique Gonzalez
Amar Halilovic
Tobias Halmdienst
Mahimul Islam
Julian Jara-Ettinger
Natalie Kastel
Renana Keydar
Ashish K. Khanna
Mahdi Khoramshahi
Jihyun Kim
Mihyeon Kim
Youngbin Kim
Senka Krivic
Nikita Krasnytskyi
Arun Kumar
Junehyoung Kwon
EunJu Lee
Shane Lee
Peter R. Lewis 0001
Xue Li
Yijiang Li
Michal Lewandowski
Nathan Lloyd
Matthew B. Luebbers
Dezhi Luo
Haiyun Lyu
Dwarikanath Mahapatra
Kamal Maheshwari
Mallika Mainali
P. Mathur
Patrick Mederitsch
Shuwa Miura
Manuel Preston de Miranda
Reuth Mirsky
Shreya Mishra
Nina M. Moorman
Katelyn Morrison
John Muchovej
Bernhard Nessler
Felix Nessler
Hieu Minh Jord Nguyen
Abby Ortego
F. Papay
Antoine Pasquali
Hamed Rahimi
C. Raghu
Amanda L. Royka
Stefan Sarkadi
Jaelle Scheuerman
Simon Schmid
Paul Schrater
Anik Sen
Zahra Sheikhbahaee
Ke Shi
Reid G. Simmons
Nishant Singh
Mason O. Smith
Ramira van der Meulen
Anthia Solaki
Haoran Sun
Viktor Szolga
Matthew E. Taylor
Travis Taylor
Sanne van Waveren
Juan David Vargas
R. Verbrugge
Eitan Wagner
Justin D. Weisz
Ximing Wen
William Yeoh
Wenlong Zhang
Michelle Zhao
Shlomo Zilberstein
2025-04-30
arXiv (published)
doi.org
arxiv.org
Cortical differences across psychiatric disorders and associated common and rare genetic variants
Kuldeep Kumar
Zhijie Liao
Jakub Kopal
Clara Moreau
Christopher R. K. Ching
Claudia Modenato
Will Snyder
Sayeh Kazem
Charles-Olivier Martin
C.O. Martin
Anne-Marie Bélanger
Valérie K. Fontaine
Khadije Jizi
Rune Boen
Guillaume Huguet
Zohra Saci
Leila Kushan
Ana I. Silva
Marianne B.M. van den Bree
David E.J. Linden … (see 16 more)
Michael J. Owen
Jeremy Hall
Sarah Lippé
Guillaume Dumas
Bogdan Draganski
Laura Almasy
Sophia I. Thomopoulos
Neda Jahanshad
Ida E. Sønderby
Ole A. Andreassen
David C. Glahn
Armin Raznahan
Carrie Bearden
Tomáš Paus
Paul M. Thompson
Sébastien Jacquemont
2025-04-18
medRxiv (preprint)
doi.org
Online HD-tRNS over the right temporoparietal junction modulates social inference but not motor coordination
Quentin Moreau
Vincent Chamberland
Lisane Moses
Gabriela Milanova
Guillaume Dumas
Social interactions are fundamental to human cognition, with the right temporoparietal junction (rTPJ) playing a key role in integrating mot… (see more)or coordination and social inference. While transcranial random noise stimulation (tRNS) is a promising technique for modulating cortical excitability in real time, its effect on dynamic social processes remains largely unexplored. This study applied high-definition tRNS (HD-tRNS) over the rTPJ during an interactive task to modulate motor coordination and social inference. Eighty neurotypical adults (49 female) were equally distributed across two experiments: Experiment 1, a block design with randomized active and sham stimulation blocks; or Experiment 2, a trial-by-trial design with intermixed stimulation protocols. Participants performed a coordination task with a covert virtual partner programmed to behave cooperatively or competitively. Kinematic data and self-reported attributions of humanness and cooperativeness were analyzed. The results showed that HD-tRNS over the rTPJ did not affect motor coordination or overall task performance in either experiment. However, in Experiment 1, active stimulation progressively reduced attributed humanness and cooperativeness toward the competitive virtual partner, suggesting enhanced detection of antagonistic intent. This gradual modulation of social inference was absent in Experiment 2, where frequent protocol switching likely disrupted the buildup of stimulation effects. Together, these findings highlight the rTPJ's causal role in self–other distinction, underscore the importance of stimulation protocol design in shaping social cognition, and support the exploration of targeted neuromodulation in clinical and developmental populations with atypical social cognition.
2025-04-18
eNeuro (published)
doi.org
Alcohol related hepatitis in intensive care units: clinical and biological spectrum and mortality risk factors: a multicenter retrospective study
Maxime Gasperment
Léa Duhaut
Nicolas Terzi
Côme Gerard
Luc Haudebourg
Alexandre Demoule
Mialy Randrianarisoa
Vincent Castelain
Sacha Sarfati
Fabienne Tamion
Charlene Le Moal
Christophe Guitton
Gabriel Preda
Arnaud Galbois
Thibault Vieille
Gaël Piton
Marika Rudler
Guillaume Dumas
Hafid AIT-OUFELLA
Background Alcohol related hepatitis is responsible for high morbidity and mortality, but little is known about the management of patients w… (see more)ith hepatitis specifically in intensive care units (ICU). Methods Retrospective study including patients with alcohol related hepatitis hospitalized in 9 French ICUs (2006–2017). Alcohol related hepatitis was defined histologically or by an association of clinical and biological criteria according to current guidelines. Results 187 patients (median age: 53 [43–60]; male: 69%) were included. A liver biopsy was performed in 51% of cases. Patients were admitted for impaired consciousness (71%), sepsis (64%), shock (44%), respiratory failure (37%). At admission, median SOFA and MELD scores were 10 [7–13] and 31 [26–40] respectively. 63% of patients received invasive mechanical ventilation, 62% vasopressors, and 36% renal replacement therapy. 66% of patients received corticosteroids, and liver transplantation was performed in 16 patients (8.5%). ICU and in-hospital mortality were 37% and 53% respectively. By multivariate analysis, ICU mortality was associated with SOFA score (without total bilirubin) (SHR 1.08 [1.02–1.14] per one-point increase), arterial lactate (SHR 1.08 [1.03–1.13] per 1 mmol/L) and MELD score (SHR 1.09 [1.04–1.14] per 1 point), while employment was associated with increased survival (HR 0.49 [0.28–0.86]). After propensity score weighting, the use of corticosteroids did not affect ICU mortality in the overall population but had a beneficial effect in the subgroup of patients with histological proof. Patient prognosis was also better in responders assessed by Lille score at day 7 (OR 6.67 [2.44–20.15], p  0.001). Conclusion Alcohol related hepatitis is a severe condition leading to high mortality in ICU patients. Severity of organ failure
2025-04-14
Annals of Intensive Care (published)
doi.org