Portrait of Guillaume Dumas

Guillaume Dumas

Associate Academic Member
Associate Professor, Université de Montréal, Department of Psychiatry and Addiction
Adjunct Professor, McGill University, Department of Psychiatry
Research Topics
Computational Biology
Computational Neuroscience
Deep Learning
Dynamical Systems
Machine Learning Theory
Medical Machine Learning
Reinforcement Learning

Biography

Guillaume Dumas is an associate professor of computational psychiatry in the Faculty of Medicine, Université de Montréal, and principal investigator in the Precision Psychiatry and Social Physiology laboratory at the Centre hospitalier universitaire (CHU) Sainte-Justine Research Centre. He holds the IVADO professorship for AI in Mental Health, and the Fonds de recherche du Québec - Santé (FRQS) J1 in AI and Digital Health. In 2023, Dumas was recognized as a CIFAR Azrieli Global Scholar – Brain, Mind, and Consciousness program, and nominated as a Future Leader in Canadian Brain Research by the Brain Canada Foundation.

Dumas was previously a permanent researcher in neuroscience and computational biology at the Institut Pasteur (Paris). Before that, he was a postdoctoral fellow at the Center for Complex Systems and Brain Sciences (Florida Atlanta University). He holds an engineering degree in advanced engineering and computer science (École Centrale Paris), two MSc degrees (theoretical physics, Paris-Saclay University; cognitive science, ENS/EHESS/Paris 5), and a PhD in cognitive neuroscience (Sorbonne University).

The goal of his research is to cross-fertilize AI/ML, cognitive neuroscience and digital medicine through an interdisciplinary program with two main axes:

- AI/ML for Mental Health, which aims to create new algorithms to investigate the development of human cognitive architecture and deliver personalized medicine in neuropsychiatry using data from genomes to smartphones.

- Social Neuroscience for AI/ML, which translates basic brain research and dynamical systems formalism into neurocomputational and machine learning hybrid models (NeuroML) and machines with social learning abilities (Social NeuroAI & HMI).

Current Students

Postdoctorate - Université de Montréal
Master's Research - Université de Montréal
Independent visiting researcher - CHU Sainte Justine / Université de Montréal
Master's Research - Université de Montréal
Principal supervisor :
PhD - Université de Montréal
Principal supervisor :

Publications

Introducing Brain Foundation Models
Hena Ghonia
Bruno Aristimunha
Md Rifat Arefin
Sylvain Chevallier
Brain function represents one of the most complex systems driving our world. Decoding its signals poses significant challenges, particularly… (see more) due to the limited availability of data and the high cost of recordings. The existence of large hospital datasets and laboratory collections partially mitigates this issue. However, the lack of standardized recording protocols, varying numbers of channels, diverse setups, scenarios, and recording devices further complicate the task. This work addresses these challenges by introducing the Brain Foundation Model (BFM), a suite of open-source models trained on brain signals. These models serve as foundational tools for various types of time-series neuroimaging tasks. This work presents the first model of the BFM series, which is trained on electroencephalogram signal data. Our results demonstrate that BFM-EEG can generate signals more accurately than other models. Upon acceptance, we will release the model weights and pipeline.
LLMs and Personalities: Inconsistencies Across Scales
This study investigates the application of human psychometric assessments to large language models (LLMs) to examine their consistency and m… (see more)alleability in exhibiting personality traits. We administered the Big Five Inventory (BFI) and the Eysenck Personality Questionnaire-Revised (EPQ-R) to various LLMs across different model sizes and persona prompts. Our results reveal substantial variability in responses due to question order shuffling, challenging the notion of a stable LLM "personality." Larger models demonstrated more consistent responses, while persona prompts significantly influenced trait scores. Notably, the assistant persona led to more predictable scaling, with larger models exhibiting more socially desirable and less variable traits. In contrast, non-conventional personas displayed unpredictable behaviors, sometimes extending personality trait scores beyond the typical human range. These findings have important implications for understanding LLM behavior under different conditions and reflect on the consequences of scaling.
Long-term outcomes of critically ill patients with hematological malignancies: what is the impact of the coronavirus disease 2019 pandemic? Author's reply
Laveena Munshi
Sangeeta Mehta
Diagnostic tests for infections in critically ill immunocompromised patients
Adrien Joseph
Lara Zafrani
Non-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain
Aliénor Delsart
Aude Castel
Colombe Otis
Mathieu Lachance
Maude Barbeau-Grégoire
Bertrand Lussier
Franck Péron
Marc Hébert
Nicolas Lapointe
Maxim Moreau
Johanne Martel-Pelletier
Jean-Pierre Pelletier
Eric Troncy
Oxygen thresholds in critically ill patients: need for personalized targets. Author's reply.
Laveena Munshi
Scalable Approaches for a Theory of Many Minds
A major challenge as we move towards building agents for real-world problems, which could involve a massive number of human and/or machine a… (see more)gents, is that we must learn to reason about the behavior of these many other agents. In this paper, we consider the problem of scaling a predictive Theory of Mind (ToM) model to a very large number of interacting agents with a fixed computational budget. Motivated by the limited diversity of agent types, existing approaches to scalable TOM learn versatile single-agent representations for quickly adapting to new agents encountered sequentially. We consider the more general setting that many agents are observed in parallel and formulate the corresponding Theory of Many Minds (ToMM) problem of estimating the joint policy. We frame the scaling behavior of solutions in terms of parameter sharing schemes and in particular propose two parameter-free architectural features that endow models with the ability to exploit action correlations: encoding a multi-agent context, and decoding through an abstracted joint action space. The increased predictive capabilities that have come with foundation models have made it easier to imagine the possibility of using these models to make simulations that imitate the behavior of many agents within complex real-world systems. Being able to perform these simulations in a general-purpose way would not only help make more capable agents, it also would be a very useful capability for applications in social science, political science, and economics.
Lost in Translation: The Algorithmic Gap Between LMs and the Brain
Tosato Tommaso
Tikeng Notsawo Pascal Junior
Helbling Saskia
Language Models (LMs) have achieved impressive performance on various linguistic tasks, but their relationship to human language processing … (see more)in the brain remains unclear. This paper examines the gaps and overlaps between LMs and the brain at different levels of analysis, emphasizing the importance of looking beyond input-output behavior to examine and compare the internal processes of these systems. We discuss how insights from neuroscience, such as sparsity, modularity, internal states, and interactive learning, can inform the development of more biologically plausible language models. Furthermore, we explore the role of scaling laws in bridging the gap between LMs and human cognition, highlighting the need for efficiency constraints analogous to those in biological systems. By developing LMs that more closely mimic brain function, we aim to advance both artificial intelligence and our understanding of human cognition.
Bringing together multimodal and multilevel approaches to study the emergence of social bonds between children and improve social AI
Julie Bonnaire
Justine Cassell
This protocol paper outlines an innovative multimodal and multilevel approach to studying the emergence and evolution of how children build … (see more)social bonds with their peers, and its potential application to improving social artificial intelligence (AI). We detail a unique hyperscanning experimental framework utilizing functional near-infrared spectroscopy (fNIRS) to observe inter-brain synchrony in child dyads during collaborative tasks and social interactions. Our proposed longitudinal study spans middle childhood, aiming to capture the dynamic development of social connections and cognitive engagement in naturalistic settings. To do so we bring together four kinds of data: the multimodal conversational behaviors that dyads of children engage in, evidence of their state of interpersonal rapport, collaborative performance on educational tasks, and inter-brain synchrony. Preliminary pilot data provide foundational support for our approach, indicating promising directions for identifying neural patterns associated with productive social interactions. The planned research will explore the neural correlates of social bond formation, informing the creation of a virtual peer learning partner in the field of Social Neuroergonomics. This protocol promises significant contributions to understanding the neural basis of social connectivity in children, while also offering a blueprint for designing empathetic and effective social AI tools, particularly for educational contexts.
295. Rare Variant Genetic Architecture of the Human Cortical MRI Phenotypes in General Population
Kuldeep Kumar
Sayeh Kazem
Zhijie Liao
Thomas Renne
Martineau Jean‐Louis
Zhe Xie
Zohra Saci
Laura Almasy
David C. Glahn
Tomáš Paus
Carrie E. Bearden
Paul M. Thompson
Richard A. I. Bethlehem
Varun Warrier
Sébastien Jacquemont
Association between arterial oxygen and mortality across critically ill patients with hematologic malignancies: results from an international collaborative network
Idunn S. Morris
Tamishta Hensman
Alexandre Demoule
Achille Kouatchet
Virginie Lemiale
Djamel Mokart
Frédéric Pène
Elie Azoulay
Laveena Munshi
Laurent François Dominique Naike Fabrice Emmanuel Yves Mic Argaud Barbier Benoit Bigé Bruneel Canet Cohen Dar
Laurent Argaud
François Barbier
Dominique Benoit
Naike Bigé
Fabrice Bruneel
Emmanuel Canet
Yves Cohen
Michael Darmon
Didier Gruson … (see 31 more)
Kada Klouche
Loay Kontar
Alexandre Lautrette
Christine Lebert
Guillaume Louis
Julien Mayaux
Anne-Pascale Meert
Anne-Sophie Moreau
Martine Nyunga
Vincent Peigne
Pierre Perez
Jean Herlé Raphalen
Carole Schwebel
Jean-Marie Tonnelier
Florent Wallet
Lara Zafrani
Bram Rochwerg
Farah Shoukat
Dean Fergusson
Bruno Ferreyro
Paul Heffernan
Margaret Herridge
Sheldon Magder
Mark Minden
Rakesh Patel
Salman Qureshi
Aaron Schimmer
Santhosh Thyagu
Han Ting Wang
Sangeeta Mehta
Sean M. Bagshaw
On quasi-homomorphism rigidity for lattices in simple algebraic groups