Portrait of Guillaume Dumas

Guillaume Dumas

Associate Academic Member
Associate Professor, Université de Montréal, Department of Psychiatry and Addiction
Adjunct Professor, McGill University, Department of Psychiatry
Research Topics
Computational Biology
Computational Neuroscience
Deep Learning
Dynamical Systems
Machine Learning Theory
Medical Machine Learning
Reinforcement Learning
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Google Scholar
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Biography

Guillaume Dumas is an associate professor of computational psychiatry in the Faculty of Medicine, Université de Montréal, and principal investigator in the Precision Psychiatry and Social Physiology laboratory at the Centre hospitalier universitaire (CHU) Sainte-Justine Research Centre. He holds the IVADO professorship for AI in Mental Health, and the Fonds de recherche du Québec - Santé (FRQS) J1 in AI and Digital Health. In 2023, Dumas was recognized as a CIFAR Azrieli Global Scholar – Brain, Mind, and Consciousness program, and nominated as a Future Leader in Canadian Brain Research by the Brain Canada Foundation.

Dumas was previously a permanent researcher in neuroscience and computational biology at the Institut Pasteur (Paris). Before that, he was a postdoctoral fellow at the Center for Complex Systems and Brain Sciences (Florida Atlanta University). He holds an engineering degree in advanced engineering and computer science (École Centrale Paris), two MSc degrees (theoretical physics, Paris-Saclay University; cognitive science, ENS/EHESS/Paris 5), and a PhD in cognitive neuroscience (Sorbonne University).

The goal of his research is to cross-fertilize AI/ML, cognitive neuroscience and digital medicine through an interdisciplinary program with two main axes:

- AI/ML for Mental Health, which aims to create new algorithms to investigate the development of human cognitive architecture and deliver personalized medicine in neuropsychiatry using data from genomes to smartphones.

- Social Neuroscience for AI/ML, which translates basic brain research and dynamical systems formalism into neurocomputational and machine learning hybrid models (NeuroML) and machines with social learning abilities (Social NeuroAI & HMI).

Current Students

Juan David Vargas
Master's Research - Université de Montréal
Kastel Natalie
PhD - Université de Montréal
Mahta Ramezanian
Master's Research - Université de Montréal
Principal supervisor :
Irina Rish
Zahra Sheikhbahaee
Postdoctorate - Université de Montréal
Co-supervisor :
Irina Rish
Github
Pascal Tikeng Notsawo
PhD - Université de Montréal
Principal supervisor :
Guillaume Rabusseau
Website
Github
Google Scholar
Tommaso Tosato
Postdoctorate - Université de Montréal
Website
Github
Google Scholar

Publications

Genetic correlates of phenotypic heterogeneity in autism
Varun Warrier
Xinhe Zhang
Patrick Reed
Alexandra Havdahl
Tyler M. Moore
Freddy Cliquet
Claire Leblond
Thomas Rolland
Anders Rosengren
Antonia San Jose Hannah Daisy Jessica Jessica Claire Bethany Eva Tony Declan Rosemary Jack Jessica Nicola Meng-Chuan Gwilym Amber Emily Hisham Julia Sara Ambrosino Sarai Yvonne Tabitha Miriam Alyssia Iris Maarten Anna Ver Loren Nico Sarah Larry Carsten Annika Daniel Ineke Yvette Maartje Elzbieta Elodie Kristiina Rouslan Guillaume Yang-Min Thomas Caceres
Antonia San Jose Hannah Daisy Jessica Jessica Claire Betha Caceres Hayward Crawley Faulkner Sabet Ellis Oakle
Antonia San José Cáceres
Hannah Hayward
Daisy Crawley
Jessica Faulkner
Jessica Sabet
Claire Ellis
Beth Oakley
Eva Loth
Tony Charman … (see 67 more)
Declan Murphy
Rosemary Holt
Jack Waldman
Jessica Upadhyay
Nicola Gunby
Meng-Chuan Lai
Gwilym Renouf
Amber N. V. Ruigrok
Emily Taylor
Hisham Ziauddeen
Julia Deakin
Sara Ambrosino di Bruttopilo
Sarai van Dijk
Yvonne Rijks
Tabitha Koops
Miriam Douma
Alyssia Spaan
Iris Selten
Maarten Steffers
Anna Ver Loren van Themaat
Nico Bast
Sarah Baumeister
Larry O’Dwyer
Carsten Bours
Annika Rausch
Daniel von Rhein
Ineke Cornelissen
Yvette de Bruin
Maartje Graauwmans
Elzbieta Kostrzewa
Elodie Cauvet
Kristiina Tammimies
Rouslan Sitnikow
Guillaume Dumas
Yang-Min Kim
Thomas Bourgeron
David M. Jonas Thomas Preben Bo Ole Merete Hougaard
David M. Hougaard
Jonas Bybjerg-Grauholm
Thomas Werge
Preben Bo Mortensen
Ole Mors
Merete Nordentoft
Dwaipayan Armandina Carrie Isabelle Tracey Paula Alex Graham J. Alexander E. P. Lidia V. Tal Madeline A. Deepak P. Jonathan Adhya
Dwaipayan Armandina Carrie Isabelle Tracey Paula Alex Graham Adhya Alamanza Allison Garvey Parsons Smith Tsompa
Dwaipayan Adhya
Armandina Alamanza
Carrie Allison
Isabelle Garvey
Tracey Parsons
Paula Smith
Alex Tsompanidis
Graham J. Burton
Alexander E. P. Heazell
Lidia V. Gabis
Tal Biron-Shental
Madeline A. Lancaster
Deepak P. Srivastava
Jonathan Mill
David H. Rowitch
Matthew E. Hurles
Daniel H. Geschwind
Anders D. Børglum
Elise B. Robinson
Jakob Grove
Hilary C. Martin
Simon Baron-Cohen
2022-06-02
Nature Genetics (published)
doi.org
From inter‐brain connectivity to inter‐personal psychiatry
Guillaume Dumas
2022-05-07
World Psychiatry (published)
doi.org
Social Neuro AI: Social Interaction as the “Dark Matter” of AI
Samuele Bolotta
Guillaume Dumas
2022-05-06
Frontiers in Computer Science (published)
doi.org
arxiv.org
P397. Genomic Deletions and Duplications Show Mirror Effects on Cognitive Ability According to Spatial Patterns of Gene Expression in the Human Brain
Kuldeep Kumar
Sayeh Kazem
Guillaume Huguet
Elise Douard
Zohra Saci
Laura Almasy
David C. Glahn
Guillaume Dumas
Sébastien Jacquemont
2022-05-01
Biological Psychiatry (published)
doi.org
A neurodynamic model of inter-brain coupling in the gamma band
Quentin Moreau
Lena Adel
Douglas Caitriona
Ranjbaran Ghazaleh
Guillaume Dumas
2022-04-11
bioRxiv (preprint)
doi.org
Naming Autism in the Right Context.
Andres Roman-Urrestarazu
Guillaume Dumas
Varun Warrier
2022-04-04
JAMA pediatrics (published)
doi.org
Neurobiological Correlates of Change in Adaptive Behavior in Autism.
Charlotte M. Pretzsch
Tim Schäfer
Michael V. Lombardo
Varun Warrier
Caroline Mann
Anke Bletsch
Chris H. Chatham
Dorothea L. Floris
Julian Tillmann
Afsheen Yousaf
Emily J. H. Jones
Tony Charman
Sara Ambrosino
Thomas Bourgeron
Guillaume Dumas
Eva Loth
Beth Oakley
Jan K. Buitelaar
Freddy Cliquet
Claire Leblond … (see 7 more)
Simon Baron-Cohen
Christian Beckmann
Tobias Banaschewski
Sarah Durston
Christine M. Freitag
Declan Murphy
Christine Ecker
2022-03-25
American Journal of Psychiatry (published)
doi.org
WOODS: Benchmarks for Out-of-Distribution Generalization in Time Series Tasks
Jean-Christophe Gagnon-Audet
Kartik Ahuja
Mohammad Javad Darvishi Bayazi
Guillaume Dumas
Irina Rish
2022-03-18
ArXiv (preprint)
doi.org
arxiv.org
Interindividual Differences in Cortical Thickness and Their Genomic Underpinnings in Autism Spectrum Disorder.
Christine Ecker
Charlotte M. Pretzsch
Anke Bletsch
Caroline Mann
Tim Schaefer
Sara Ambrosino
Julian Tillmann
Afsheen Yousaf
Andreas Chiocchetti
Michael V. Lombardo
Varun Warrier
Nico Bast
Carolin Moessnang
Sarah Baumeister
Flavio Dell’Acqua
Dorothea L. Floris
Mariam Zabihi
Andre Marquand
Freddy Cliquet
Claire Leblond … (see 19 more)
Clara A. Moreau
Nick Puts
Tobias Banaschewski
Emily J. H. Jones
Luke Mason
Sven Bölte
Andreas Meyer-Lindenberg
Antonio Persico
Sarah Durston
Simon Baron-Cohen
Will Spooren
Eva Loth
Christine M. Freitag
Tony Charman
Guillaume Dumas
Thomas Bourgeron
Christian Beckmann
Jan K. Buitelaar
Declan Murphy
2022-03-01
American Journal of Psychiatry (published)
doi.org
Patterns of connectome variability in autism across five functional activation tasks: findings from the LEAP project
Tristan Looden
Dorothea L. Floris
Alberto Llera
R. Chauvin
Jumana Sara Bonnie Tobias Simon Sarah Christian F. Sven T Ahmad Ambrosino Auyeung Banaschewski Baron-Cohen B
Jumana Ahmad
Sara Ambrosino
Bonnie Auyeung
Tobias Banaschewski
Simon Baron-Cohen
Sarah Baumeister
Christian Beckmann
Sven Bölte
Thomas Bourgeron
Carsten Bours
Michael Brammer
Daniel Brandeis
Claudia Brogna
Yvette de Bruijn
Jan K. Buitelaar … (see 55 more)
Bhismadev Chakrabarti
Tony Charman
Ineke Cornelissen
Daisy Crawley
F. D. Acqua
Guillaume Dumas
Sarah Durston
Christine Ecker
Jessica Faulkner
Vincent Frouin
Pilar Garcés
David Goyard
Lindsay Ham
Hannah Hayward
Joerg F. Hipp
Rosemary Holt
Mark Johnson
Emily J. H. Jones
Prantik Kundu
Meng-Chuan Lai
Xavier Liogier D’ardhuy
Michael V. Lombardo
Eva Loth
David J. Lythgoe
René Mandl
Andre Marquand
Luke Mason
Maarten Mennes
Andreas Meyer-Lindenberg
Carolin Moessnang
Nico Mueller
Declan Murphy
Beth Oakley
Laurence O’Dwyer
Marianne Oldehinkel
Bob Oranje
Gahan Pandina
Antonio Persico
Annika Rausch
Barbara Ruggeri
Amber N. V. Ruigrok
Jessica Sabet
Roberto Sacco
Antonia San José Cáceres
Emily Simonoff
Will Spooren
Julian Tillmann
Roberto Toro
Heike Tost
Jack Waldman
Steven C. R. Williams
Caroline Wooldridge
Iva Ilioska
Ting Mei
Marcel P. Zwiers
2022-02-23
bioRxiv (preprint)
doi.org
Multilevel development of cognitive abilities in an artificial neural network
Konstantin Volzhenin
J. Changeux
Guillaume Dumas
Several neuronal mechanisms have been proposed to account for the formation of cognitive abilities through postnatal interactions with the p… (see more)hysical and socio-cultural environment. Here, we introduce a three-level computational model of information processing and acquisition of cognitive abilities. We propose minimal architectural requirements to build these levels and how the parameters affect their performance and relationships. The first sensorimotor level handles local nonconscious processing, here during a visual classification task. The second level or cognitive level globally integrates the information from multiple local processors via long-ranged connections and synthesizes it in a global, but still nonconscious manner. The third and cognitively highest level handles the information globally and consciously. It is based on the Global Neuronal Workspace (GNW) theory and is referred to as conscious level. We use trace and delay conditioning tasks to, respectively, challenge the second and third levels. Results first highlight the necessity of epigenesis through selection and stabilization of synapses at both local and global scales to allow the network to solve the first two tasks. At the global scale, dopamine appears necessary to properly provide credit assignment despite the temporal delay between perception and reward. At the third level, the presence of interneurons becomes necessary to maintain a self-sustained representation within the GNW in the absence of sensory input. Finally, while balanced spontaneous intrinsic activity facilitates epigenesis at both local and global scales, the balanced excitatory-inhibitory ratio increases performance. Finally, we discuss the plausibility of the model in both neurodevelopmental and artificial intelligence terms.
2022-01-25
bioRxiv (preprint)
doi.org
Multilevel development of cognitive abilities in an artificial neural network
Konstantin Volzhenin
Jean-Pierre Changeux
Guillaume Dumas
Several neuronal mechanisms have been proposed to account for the formation of cognitive abilities through postnatal interactions with the p… (see more)hysical and socio-cultural environment. Here, we introduce a three-level computational model of information processing and acquisition of cognitive abilities. We propose minimal architectural requirements to build these levels and how the parameters affect their performance and relationships. The first sensorimotor level handles local nonconscious processing, here during a visual classification task. The second level or cognitive level globally integrates the information from multiple local processors via long-ranged connections and synthesizes it in a global, but still nonconscious manner. The third and cognitively highest level handles the information globally and consciously. It is based on the Global Neuronal Workspace (GNW) theory and is referred to as conscious level. We use trace and delay conditioning tasks to, respectively, challenge the second and third levels. Results first highlight the necessity of epigenesis through selection and stabilization of synapses at both local and global scales to allow the network to solve the first two tasks. At the global scale, dopamine appears necessary to properly provide credit assignment despite the temporal delay between perception and reward. At the third level, the presence of interneurons becomes necessary to maintain a self-sustained representation within the GNW in the absence of sensory input. Finally, while balanced spontaneous intrinsic activity facilitates epigenesis at both local and global scales, the balanced excitatory-inhibitory ratio increases performance. Finally, we discuss the plausibility of the model in both neurodevelopmental and artificial intelligence terms.
2022-01-25
bioRxiv (preprint)
doi.org