Publications

Multilevel development of cognitive abilities in an artificial neural network
Konstantin Volzhenin
Jean-Pierre Changeux
Guillaume Dumas
Several neuronal mechanisms have been proposed to account for the formation of cognitive abilities through postnatal interactions with the p… (see more)hysical and socio-cultural environment. Here, we introduce a three-level computational model of information processing and acquisition of cognitive abilities. We propose minimal architectural requirements to build these levels and how the parameters affect their performance and relationships. The first sensorimotor level handles local nonconscious processing, here during a visual classification task. The second level or cognitive level globally integrates the information from multiple local processors via long-ranged connections and synthesizes it in a global, but still nonconscious manner. The third and cognitively highest level handles the information globally and consciously. It is based on the Global Neuronal Workspace (GNW) theory and is referred to as conscious level. We use trace and delay conditioning tasks to, respectively, challenge the second and third levels. Results first highlight the necessity of epigenesis through selection and stabilization of synapses at both local and global scales to allow the network to solve the first two tasks. At the global scale, dopamine appears necessary to properly provide credit assignment despite the temporal delay between perception and reward. At the third level, the presence of interneurons becomes necessary to maintain a self-sustained representation within the GNW in the absence of sensory input. Finally, while balanced spontaneous intrinsic activity facilitates epigenesis at both local and global scales, the balanced excitatory-inhibitory ratio increases performance. Finally, we discuss the plausibility of the model in both neurodevelopmental and artificial intelligence terms.
2022-01-25
bioRxiv (preprint)
doi.org
Neural correlates of local parallelism during naturalistic vision
John Wilder
Morteza Rezanejad
Sven J. Dickinson
Kaleem Siddiqi
A. Jepson
Dirk. B. Walther
Human observers can rapidly perceive complex real-world scenes. Grouping visual elements into meaningful units is an integral part of this p… (see more)rocess. Yet, so far, the neural underpinnings of perceptual grouping have only been studied with simple lab stimuli. We here uncover the neural mechanisms of one important perceptual grouping cue, local parallelism. Using a new, image-computable algorithm for detecting local symmetry in line drawings and photographs, we manipulated the local parallelism content of real-world scenes. We decoded scene categories from patterns of brain activity obtained via functional magnetic resonance imaging (fMRI) in 38 human observers while they viewed the manipulated scenes. Decoding was significantly more accurate for scenes containing strong local parallelism compared to weak local parallelism in the parahippocampal place area (PPA), indicating a central role of parallelism in scene perception. To investigate the origin of the parallelism signal we performed a model-based fMRI analysis of the public BOLD5000 dataset, looking for voxels whose activation time course matches that of the locally parallel content of the 4916 photographs viewed by the participants in the experiment. We found a strong relationship with average local symmetry in visual areas V1-4, PPA, and retrosplenial cortex (RSC). Notably, the parallelism-related signal peaked first in V4, suggesting V4 as the site for extracting paralleism from the visual input. We conclude that local parallelism is a perceptual grouping cue that influences neuronal activity throughout the visual hierarchy, presumably starting at V4. Parallelism plays a key role in the representation of scene categories in PPA.
2022-01-21
PLoS ONE (published)
doi.org
Neural correlates of local parallelism during naturalistic vision
John Wilder
Morteza Rezanejad
Sven Dickinson
Kaleem Siddiqi
Allan Jepson
Dirk B. Walther
Human observers can rapidly perceive complex real-world scenes. Grouping visual elements into meaningful units is an integral part of this p… (see more)rocess. Yet, so far, the neural underpinnings of perceptual grouping have only been studied with simple lab stimuli. We here uncover the neural mechanisms of one important perceptual grouping cue, local parallelism. Using a new, image-computable algorithm for detecting local symmetry in line drawings and photographs, we manipulated the local parallelism content of real-world scenes. We decoded scene categories from patterns of brain activity obtained via functional magnetic resonance imaging (fMRI) in 38 human observers while they viewed the manipulated scenes. Decoding was significantly more accurate for scenes containing strong local parallelism compared to weak local parallelism in the parahippocampal place area (PPA), indicating a central role of parallelism in scene perception. To investigate the origin of the parallelism signal we performed a model-based fMRI analysis of the public BOLD5000 dataset, looking for voxels whose activation time course matches that of the locally parallel content of the 4916 photographs viewed by the participants in the experiment. We found a strong relationship with average local symmetry in visual areas V1-4, PPA, and retrosplenial cortex (RSC). Notably, the parallelism-related signal peaked first in V4, suggesting V4 as the site for extracting paralleism from the visual input. We conclude that local parallelism is a perceptual grouping cue that influences neuronal activity throughout the visual hierarchy, presumably starting at V4. Parallelism plays a key role in the representation of scene categories in PPA.
2022-01-21
PLoS ONE (published)
doi.org
Digital Ageism: Challenges and Opportunities in Artificial Intelligence for Older Adults
Charlene H Chu
Rune Nyrup
Kathleen Leslie
Jiamin Shi
Andria Bianchi
Alexandra Lyn
Molly McNicholl
Shehroz S Khan
Samira Abbasgholizadeh-Rahimi
A. Grenier
Abstract Artificial intelligence (AI) and machine learning are changing our world through their impact on sectors including health care, edu… (see more)cation, employment, finance, and law. AI systems are developed using data that reflect the implicit and explicit biases of society, and there are significant concerns about how the predictive models in AI systems amplify inequity, privilege, and power in society. The widespread applications of AI have led to mainstream discourse about how AI systems are perpetuating racism, sexism, and classism; yet, concerns about ageism have been largely absent in the AI bias literature. Given the globally aging population and proliferation of AI, there is a need to critically examine the presence of age-related bias in AI systems. This forum article discusses ageism in AI systems and introduces a conceptual model that outlines intersecting pathways of technology development that can produce and reinforce digital ageism in AI systems. We also describe the broader ethical and legal implications and considerations for future directions in digital ageism research to advance knowledge in the field and deepen our understanding of how ageism in AI is fostered by broader cycles of injustice.
2022-01-20
The gerontologist (published)
doi.org
Digital Ageism: Challenges and Opportunities in Artificial Intelligence for Older Adults
Charlene H Chu
Rune Nyrup
Kathleen Leslie
Jiamin Shi
Andria Bianchi
Alexandra Lyn
Molly McNicholl
Shehroz S Khan
Samira Abbasgholizadeh-Rahimi
Amanda Grenier
Abstract Artificial intelligence (AI) and machine learning are changing our world through their impact on sectors including health care, edu… (see more)cation, employment, finance, and law. AI systems are developed using data that reflect the implicit and explicit biases of society, and there are significant concerns about how the predictive models in AI systems amplify inequity, privilege, and power in society. The widespread applications of AI have led to mainstream discourse about how AI systems are perpetuating racism, sexism, and classism; yet, concerns about ageism have been largely absent in the AI bias literature. Given the globally aging population and proliferation of AI, there is a need to critically examine the presence of age-related bias in AI systems. This forum article discusses ageism in AI systems and introduces a conceptual model that outlines intersecting pathways of technology development that can produce and reinforce digital ageism in AI systems. We also describe the broader ethical and legal implications and considerations for future directions in digital ageism research to advance knowledge in the field and deepen our understanding of how ageism in AI is fostered by broader cycles of injustice.
2022-01-20
The Gerontologist (published)
doi.org
Bayesian stroke modeling details sex biases in the white matter substrates of aphasia
Julius M. Kernbach
Gesa Hartwigsen
Jae‐Sung Lim
Hee-Joon Bae
Kyung‐Ho Yu
Gottfried Schlaug
Anna K. Bonkhoff
Natalia S. Rost
Danilo Bzdok
2022-01-18
bioRxiv (preprint)
doi.org
Invariant representation driven neural classifier for anti-QCD jet tagging
Taoli Cheng
Aaron Courville
2022-01-18
ArXiv (preprint)
doi.org
arxiv.org
Biomedical Research and Informatics Living Laboratory for Innovative Advances of New Technologies in Community Mobility Rehabilitation: Protocol for Evaluation and Rehabilitation of Mobility Across Continuums of Care
Sara Ahmed
P. Archambault
Claudine Auger
Audrey Durand
Joyce Phua Pau Fung
Eva Kehayia
Anouk Lamontagne
Annette Majnemer
Sylvie Nadeau
Joelle Pineau
Alain Ptito
B. Swaine
Background Rapid advances in technologies over the past 10 years have enabled large-scale biomedical and psychosocial rehabilitation researc… (see more)h to improve the function and social integration of persons with physical impairments across the lifespan. The Biomedical Research and Informatics Living Laboratory for Innovative Advances of New Technologies (BRILLIANT) in community mobility rehabilitation aims to generate evidence-based research to improve rehabilitation for individuals with acquired brain injury (ABI). Objective This study aims to (1) identify the factors limiting or enhancing mobility in real-world community environments (public spaces, including the mall, home, and outdoors) and understand their complex interplay in individuals of all ages with ABI and (2) customize community environment mobility training by identifying, on a continuous basis, the specific rehabilitation strategies and interventions that patient subgroups benefit from most. Here, we present the research and technology plan for the BRILLIANT initiative. Methods A cohort of individuals, adults and children, with ABI (N=1500) will be recruited. Patients will be recruited from the acute care and rehabilitation partner centers within 4 health regions (living labs) and followed throughout the continuum of rehabilitation. Participants will also be recruited from the community. Biomedical, clinician-reported, patient-reported, and brain imaging data will be collected. Theme 1 will implement and evaluate the feasibility of collecting data across BRILLIANT living labs and conduct predictive analyses and artificial intelligence (AI) to identify mobility subgroups. Theme 2 will implement, evaluate, and identify community mobility interventions that optimize outcomes for mobility subgroups of patients with ABI. Results The biomedical infrastructure and equipment have been established across the living labs, and development of the clinician- and patient-reported outcome digital solutions is underway. Recruitment is expected to begin in May 2022. Conclusions The program will develop and deploy a comprehensive clinical and community-based mobility-monitoring system to evaluate the factors that result in poor mobility, and develop personalized mobility interventions that are optimized for specific patient subgroups. Technology solutions will be designed to support clinicians and patients to deliver cost-effective care and the right intervention to the right person at the right time to optimize long-term functional potential and meaningful participation in the community. International Registered Report Identifier (IRRID) PRR1-10.2196/12506
2022-01-13
JMIR Research Protocols (published)
doi.org
Biomedical Research & Informatics Living Laboratory for Innovative Advances of New Technologies in Community Mobility Rehabilitation: Protocol for a longitudinal evaluation of mobility outcomes (Preprint)
Sara Ahmed
Philippe Archambault
Claudine Auger
Audrey Durand
Joyce Fung
Eva Kehayia
Anouk Lamontagne
Annette Majnemer
Sylvie Nadeau
Joelle Pineau
Alain Ptito
Bonnie Swaine
UNSTRUCTURED The Biomedical Research and Informatics Living Laboratory for Innovative Advances of New Technologies in Community Mobility Re… (see more)habilitation (BRILLIANT) program to provide evidence-based research to improve rehabilitation for individuals with Acquired Brain Injury (ABI: traumatic brain injury [TBI], cerebral palsy-fetal/perinatal brain injury, and stroke). The vision of the BRILLIANT program is to optimize mobility of persons with ABI across the lifespan. The program will develop and deploy a comprehensive clinical and community based mobility monitoring system to evaluate the factors that result in poor mobility, and develop personalized mobility interventions that are optimized for specific patient sub-groups. These innovations will be used by front-line clinicians to deliver cost-effective care; the right intervention to the right person at the right time, accounting for long-term functional potential and meaningful participation in the community.
2022-01-13
(published)
doi.org
Grow-and-Clip: Informative-yet-Concise Evidence Distillation for Answer Explanation
Yuyan Chen
Yanghua Xiao
Bang Liu
Interpreting the predictions of existing Question Answering (QA) models is critical to many real-world intelligent applications, such as QA … (see more)systems for healthcare, education, and finance. However, existing QA models lack interpretability and provide no feedback or explanation for end-users to help them understand why a specific prediction is the answer to a question. In this research, we argue that the evidences of an answer is critical to enhancing the interpretability of QA models. Unlike previous research that simply extracts several sentence(s) in the context as evidence, we are the first to explicitly define the concept of evidence as the supporting facts in a context which are informative, concise, and readable. Besides, we provide effective strategies to quantitatively measure the informativeness, conciseness and readability of evidence. Furthermore, we propose Grow-and-Clip Evidence Distillation (GCED) algorithm to extract evidences from the contexts by trade-off informativeness, conciseness, and readability. We conduct extensive experiments on the SQuAD and TriviaQA datasets with several baseline models to evaluate the effect of GCED on interpreting answers to questions. Human evaluation are also carried out to check the quality of distilled evidences. Experimental results show that automatic distilled evidences have human-like informativeness, conciseness and readability, which can enhance the interpretability of the answers to questions.
2022-01-13
ArXiv (preprint)
doi.org
arxiv.org
Robust Contrastive Learning against Noisy Views
Ching-Yao Chuang
(Rex) Devon Hjelm
Xin Wang
Vibhav Vineet
Neel Joshi
Antonio Torralba
Stefanie Jegelka
Ya-heng Song
Contrastive learning relies on an assumption that positive pairs contain related views that share certain underlying information about an in… (see more)stance, e.g., patches of an image or co-occurring multimodal signals of a video. What if this assumption is violated? The literature suggests that contrastive learning produces suboptimal representations in the presence of noisy views, e.g., false positive pairs with no apparent shared information. In this work, we pro-pose a new contrastive loss function that is robust against noisy views. We provide rigorous theoretical justifications by showing connections to robust symmetric losses for noisy binary classification and by establishing a new contrastive bound for mutual information maximization based on the Wasserstein distance measure. The proposed loss is completely modality-agnostic and a simple drop-in replacement for the InfoNCE loss, which makes it easy to apply to ex-isting contrastive frameworks. We show that our approach provides consistent improvements over the state-of-the-art on image, video, and graph contrastive learning bench-marks that exhibit a variety of real-world noise patterns.
2022-01-12
ArXiv (preprint)
doi.org
arxiv.org
Magnetoencephalography resting-state correlates of executive and language components of verbal fluency
Victor Oswald
Younes Zerouali
Aubrée Boulet-Craig
Maja Krajinovic
Caroline Laverdière
Daniel Sinnett
Pierre Jolicoeur
Sarah Lippé
Karim Jerbi
Philippe Robaey
2022-01-10
Scientific Reports (published)
doi.org