Gaining Biological Insights through Supervised Data Visualization
Jake S. Rhodes
Adrien Aumon
Sacha Morin
Marc Girard
Catherine Larochelle
Elsa Brunet-Ratnasingham
Amélie Pagliuzza
Lorie Marchitto
Wei Zhang
Adele Cutler
F. Grand'Maison
Anhong Zhou
Andrés Finzi
Nicolas Chomont
Daniel E. Kaufmann
Stephanie Zandee
Alexandre Prat
Guy Wolf
Kevin R. Moon
Dimensionality reduction-based data visualization is pivotal in comprehending complex biological data. The most common methods, such as PHAT… (see more)E, t-SNE, and UMAP, are unsupervised and therefore reflect the dominant structure in the data, which may be independent of expert-provided labels. Here we introduce a supervised data visualization method called RF-PHATE, which integrates expert knowledge for further exploration of the data. RF-PHATE leverages random forests to capture intricate featurelabel relationships. Extracting information from the forest, RF-PHATE generates low-dimensional visualizations that highlight relevant data relationships while disregarding extraneous features. This approach scales to large datasets and applies to classification and regression. We illustrate RF-PHATE’s prowess through three case studies. In a multiple sclerosis study using longitudinal clinical and imaging data, RF-PHATE unveils a sub-group of patients with non-benign relapsingremitting Multiple Sclerosis, demonstrating its aptitude for time-series data. In the context of Raman spectral data, RF-PHATE effectively showcases the impact of antioxidants on diesel exhaust-exposed lung cells, highlighting its proficiency in noisy environments. Furthermore, RF-PHATE aligns established geometric structures with COVID-19 patient outcomes, enriching interpretability in a hierarchical manner. RF-PHATE bridges expert insights and visualizations, promising knowledge generation. Its adaptability, scalability, and noise tolerance underscore its potential for widespread adoption.
2024-01-21
bioRxiv (preprint)
doi.org
Gaining Biological Insights through Supervised Data Visualization
Jake S. Rhodes
Adrien Aumon
Sacha Morin
Marc Girard
Catherine Larochelle
Boaz Lahav
Elsa Brunet-Ratnasingham
Amélie Pagliuzza
Lorie Marchitto
Wei Zhang
Adele Cutler
F. Grand'Maison
Anhong Zhou
Andrés Finzi
Nicolas Chomont
Daniel E. Kaufmann
Stephanie Zandee
Alexandre Prat
Guy Wolf
Kevin R. Moon
Dimensionality reduction-based data visualization is pivotal in comprehending complex biological data. The most common methods, such as PHAT… (see more)E, t-SNE, and UMAP, are unsupervised and therefore reflect the dominant structure in the data, which may be independent of expert-provided labels. Here we introduce a supervised data visualization method called RF-PHATE, which integrates expert knowledge for further exploration of the data. RF-PHATE leverages random forests to capture intricate featurelabel relationships. Extracting information from the forest, RF-PHATE generates low-dimensional visualizations that highlight relevant data relationships while disregarding extraneous features. This approach scales to large datasets and applies to classification and regression. We illustrate RF-PHATE’s prowess through three case studies. In a multiple sclerosis study using longitudinal clinical and imaging data, RF-PHATE unveils a sub-group of patients with non-benign relapsingremitting Multiple Sclerosis, demonstrating its aptitude for time-series data. In the context of Raman spectral data, RF-PHATE effectively showcases the impact of antioxidants on diesel exhaust-exposed lung cells, highlighting its proficiency in noisy environments. Furthermore, RF-PHATE aligns established geometric structures with COVID-19 patient outcomes, enriching interpretability in a hierarchical manner. RF-PHATE bridges expert insights and visualizations, promising knowledge generation. Its adaptability, scalability, and noise tolerance underscore its potential for widespread adoption.
2024-01-21
bioRxiv (preprint)
doi.org
Cross-Task Affinity Learning for Multitask Dense Scene Predictions
Dimitrios Sinodinos
Narges Armanfard
2024-01-20
ArXiv (preprint)
arxiv.org
arxiv.org
EMA-Net: Efficient Multitask Affinity Learning for Dense Scene Predictions
Dimitrios Sinodinos
Narges Armanfard
2024-01-20
ArXiv (preprint)
doi.org
arxiv.org
PhotoBot: Reference-Guided Interactive Photography via Natural Language
Oliver Limoyo
Jimmy Li
Dmitriy Rivkin
Jonathan Kelly
Gregory Dudek
We introduce PhotoBot, a framework for fully automated photo acquisition based on an interplay between high-level human language guidance an… (see more)d a robot photographer. We propose to communicate photography suggestions to the user via reference images that are selected from a curated gallery. We leverage a visual language model (VLM) and an object detector to characterize the reference images via textual descriptions and then use a large language model (LLM) to retrieve relevant reference images based on a user’s language query through text-based reasoning. To correspond the reference image and the observed scene, we exploit pretrained features from a vision transformer capable of capturing semantic similarity across marked appearance variations. Using these features, we compute suggested pose adjustments for an RGB-D camera by solving a perspective-n-point (PnP) problem. We demonstrate our approach using a manipulator equipped with a wrist camera. Our user studies show that photos taken by PhotoBot are often more aesthetically pleasing than those taken by users themselves, as measured by human feedback. We also show that PhotoBot can generalize to other reference sources such as paintings.
2024-01-19
ArXiv (preprint)
doi.org
arxiv.org
PhotoBot: Reference-Guided Interactive Photography via Natural Language
Oliver Limoyo
Jimmy Li
Dmitriy Rivkin
Jonathan Kelly
Gregory Dudek
We introduce PhotoBot, a framework for fully automated photo acquisition based on an interplay between high-level human language guidance an… (see more)d a robot photographer. We propose to communicate photography suggestions to the user via reference images that are selected from a curated gallery. We leverage a visual language model (VLM) and an object detector to characterize the reference images via textual descriptions and then use a large language model (LLM) to retrieve relevant reference images based on a user’s language query through text-based reasoning. To correspond the reference image and the observed scene, we exploit pretrained features from a vision transformer capable of capturing semantic similarity across marked appearance variations. Using these features, we compute suggested pose adjustments for an RGB-D camera by solving a perspective-n-point (PnP) problem. We demonstrate our approach using a manipulator equipped with a wrist camera. Our user studies show that photos taken by PhotoBot are often more aesthetically pleasing than those taken by users themselves, as measured by human feedback. We also show that PhotoBot can generalize to other reference sources such as paintings.
2024-01-19
ArXiv (preprint)
doi.org
arxiv.org
Bridging State and History Representations: Understanding Self-Predictive RL
Tianwei Ni
Benjamin Eysenbach
Erfan SeyedSalehi
Michel Ma
Clement Gehring
Aditya Mahajan
Pierre-Luc Bacon
Representations are at the core of all deep reinforcement learning (RL) methods for both Markov decision processes (MDPs) and partially obse… (see more)rvable Markov decision processes (POMDPs). Many representation learning methods and theoretical frameworks have been developed to understand what constitutes an effective representation. However, the relationships between these methods and the shared properties among them remain unclear. In this paper, we show that many of these seemingly distinct methods and frameworks for state and history abstractions are, in fact, based on a common idea of self-predictive abstraction. Furthermore, we provide theoretical insights into the widely adopted objectives and optimization, such as the stop-gradient technique, in learning self-predictive representations. These findings together yield a minimalist algorithm to learn self-predictive representations for states and histories. We validate our theories by applying our algorithm to standard MDPs, MDPs with distractors, and POMDPs with sparse rewards. These findings culminate in a set of preliminary guidelines for RL practitioners.
2024-01-17
ArXiv (preprint)
doi.org
arxiv.org
Bridging State and History Representations: Understanding Self-Predictive RL
Tianwei Ni
Benjamin Eysenbach
Erfan SeyedSalehi
Michel Ma
Clement Gehring
Aditya Mahajan
Pierre-Luc Bacon
Representations are at the core of all deep reinforcement learning (RL) methods for both Markov decision processes (MDPs) and partially obse… (see more)rvable Markov decision processes (POMDPs). Many representation learning methods and theoretical frameworks have been developed to understand what constitutes an effective representation. However, the relationships between these methods and the shared properties among them remain unclear. In this paper, we show that many of these seemingly distinct methods and frameworks for state and history abstractions are, in fact, based on a common idea of self-predictive abstraction. Furthermore, we provide theoretical insights into the widely adopted objectives and optimization, such as the stop-gradient technique, in learning self-predictive representations. These findings together yield a minimalist algorithm to learn self-predictive representations for states and histories. We validate our theories by applying our algorithm to standard MDPs, MDPs with distractors, and POMDPs with sparse rewards. These findings culminate in a set of preliminary guidelines for RL practitioners.
2024-01-17
ArXiv (preprint)
doi.org
arxiv.org
Deployable Reinforcement Learning with Variable Control Rate
Dong Wang
Giovanni Beltrame
2024-01-17
ArXiv (preprint)
doi.org
arxiv.org
METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII
Burak Kocak
Tugba Akinci D’Antonoli
Nathaniel Mercaldo
Angel Alberich-Bayarri
Bettina Baessler
Ilaria Ambrosini
Anna E. Andreychenko
Spyridon Bakas
Regina G. H. Beets-Tan
Keno Bressem
Irene Buvat
Roberto Cannella
Luca Alessandro Cappellini
Armando Ugo Cavallo
Leonid L. Chepelev
Linda Chi Hang Chu
Aydin Demircioglu
Nandita M. deSouza
Matthias Dietzel
Salvatore Claudio Fanni … (see 40 more)
Andrey Fedorov
Laure S. Fournier
Valentina Giannini
Rossano Girometti
Kevin B. W. Groot Lipman
Georgios Kalarakis
Brendan S. Kelly
Michail E. Klontzas
Dow-Mu Koh
Elmar Kotter
Ho Yun Lee
Mario Maas
Luis Marti-Bonmati
Henning Müller
Nancy Obuchowski
Fanny Orlhac
Nikolaos Papanikolaou
Ekaterina Petrash
Elisabeth Pfaehler
Daniel Pinto dos Santos
Andrea Ponsiglione
Sebastià Sabater
Francesco Sardanelli
Philipp Seeböck
Nanna M. Sijtsema
Arnaldo Stanzione
Alberto Traverso
Lorenzo Ugga
Martin Vallières
Lisanne V. van Dijk
Joost J. M. van Griethuysen
Robbert W. van Hamersvelt
Peter van Ooijen
Federica Vernuccio
Alan Wang
Stuart Williams
Jan Witowski
Zhongyi Zhang
Alex Zwanenburg
Renato Cuocolo
2024-01-17
Insights into Imaging (published)
doi.org
METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII
Burak Kocak
Tugba Akinci D’Antonoli
Nathaniel Mercaldo
Angel Alberich-Bayarri
Bettina Baessler
Ilaria Ambrosini
Anna E. Andreychenko
Spyridon Bakas
Regina G. H. Beets-Tan
Keno Bressem
Irene Buvat
Roberto Cannella
Luca Alessandro Cappellini
Armando Ugo Cavallo
Leonid L. Chepelev
Linda Chi Hang Chu
Aydin Demircioglu
Nandita M. deSouza
Matthias Dietzel
Salvatore Claudio Fanni … (see 40 more)
Andrey Fedorov
Laure S. Fournier
Valentina Giannini
Rossano Girometti
Kevin B. W. Groot Lipman
Georgios Kalarakis
Brendan S. Kelly
Michail E. Klontzas
Dow-Mu Koh
Elmar Kotter
Ho Yun Lee
Mario Maas
Luis Marti-Bonmati
Henning Müller
Nancy Obuchowski
Fanny Orlhac
Nikolaos Papanikolaou
Ekaterina Petrash
Elisabeth Pfaehler
Daniel Pinto dos Santos
Andrea Ponsiglione
Sebastià Sabater
Francesco Sardanelli
Philipp Seeböck
Nanna M. Sijtsema
Arnaldo Stanzione
Alberto Traverso
Lorenzo Ugga
Martin Vallières
Lisanne V. van Dijk
Joost J. M. van Griethuysen
Robbert W. van Hamersvelt
Peter van Ooijen
Federica Vernuccio
Alan Wang
Stuart Williams
Jan Witowski
Zhongyi Zhang
Alex Zwanenburg
Renato Cuocolo
2024-01-17
Insights into Imaging (published)
doi.org
METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII
Burak Kocak
Tugba Akinci D’Antonoli
Nathaniel Mercaldo
Angel Alberich-Bayarri
Bettina Baessler
Ilaria Ambrosini
Anna E. Andreychenko
Spyridon Bakas
Regina G. H. Beets-Tan
Keno Bressem
Irene Buvat
Roberto Cannella
Luca Alessandro Cappellini
Armando Ugo Cavallo
Leonid L. Chepelev
Linda Chi Hang Chu
Aydin Demircioglu
Nandita M. deSouza
Matthias Dietzel
Salvatore Claudio Fanni … (see 40 more)
Andrey Fedorov
Laure S. Fournier
Valentina Giannini
Rossano Girometti
Kevin B. W. Groot Lipman
Georgios Kalarakis
Brendan S. Kelly
Michail E. Klontzas
Dow-Mu Koh
Elmar Kotter
Ho Yun Lee
Mario Maas
Luis Marti-Bonmati
Henning Müller
Nancy Obuchowski
Fanny Orlhac
Nikolaos Papanikolaou
Ekaterina Petrash
Elisabeth Pfaehler
Daniel Pinto dos Santos
Andrea Ponsiglione
Sebastià Sabater
Francesco Sardanelli
Philipp Seeböck
Nanna M. Sijtsema
Arnaldo Stanzione
Alberto Traverso
Lorenzo Ugga
Martin Vallières
Lisanne V. van Dijk
Joost J. M. van Griethuysen
Robbert W. van Hamersvelt
Peter van Ooijen
Federica Vernuccio
Alan Wang
Stuart Williams
Jan Witowski
Zhongyi Zhang
Alex Zwanenburg
Renato Cuocolo
2024-01-17
Insights into Imaging (published)
doi.org