Publications

Longitudinal intergenerational hyperscanning indexes changes in social connection
Ryssa Moffat
Guillaume Dumas
Emily S. Cross
Loneliness is globally acknowledged as a severe and burgeoning health risk, fuelling interest in helping people of all ages form meaningful … (see more)social connections. One promising approach consists of intergenerational social programs. While behavioural and qualitative evidence derived from such programs promise health and wellbeing benefits, the physiological consequences of repeated intergenerational encounters remain unknown. Insight into physiological changes will shed light on the mechanisms of social connection and can inform program design choices. We charted changes in interpersonal neural synchrony (INS) in 31 intergenerational (older/younger adult) and 30 same generation (younger adult) dyads across a six-session creative drawing program. At each session, dyads completed self-report measures, drew together and alone, and had their cortical activation recorded with fNIRS. In both groups, INS was greater while dyads drew together than alone. Across sessions, intergenerational dyads’ INS decreased and same generation dyads’ INS increased. INS in RIFG∼RTPJ and RIFG∼RIFG were predictive of loneliness levels and feelings of social closeness, respectively. The research reinforces the multi-faceted nature of INS dynamics as social connections are forged.
2025-10-14
bioRxiv (preprint)
doi.org
Measuring What Matters: Connecting AI Ethics Evaluations to System Attributes, Hazards, and Harms
Shalaleh Rismani
Renee Shelby
Leah Davis
Negar Rostamzadeh
AJung Moon
Over the past decade, an ecosystem of measures has emerged to evaluate the social and ethical implications of AI systems, largely shaped by … (see more)high-level ethics principles. These measures are developed and used in fragmented ways, without adequate attention to how they are situated in AI systems. In this paper, we examine how existing measures used in the computing literature map to AI system components, attributes, hazards, and harms. Our analysis draws on a scoping review resulting in nearly 800 measures corresponding to 11 AI ethics principles. We find that most measures focus on four principles – fairness, transparency, privacy, and trust – and primarily assess model or output system components. Few measures account for interactions across system elements, and only a narrow set of hazards is typically considered for each harm type. Many measures are disconnected from where harm is experienced and lack guidance for setting meaningful thresholds. These patterns reveal how current evaluation practices remain fragmented, measuring in pieces rather than capturing how harms emerge across systems. Framing measures with respect to system attributes, hazards, and harms can strengthen regulatory oversight, support actionable practices in industry, and ground future research in systems-level understanding.
2025-10-14
Proceedings of the AAAI/ACM Conference on AI, Ethics, and Society (published)
doi.org
arxiv.org
PoissonNet: A Local-Global Approach for Learning on Surfaces
Arman Maesumi
Tanish Makadia
Thibault Groueix
Vladimir Kim
Daniel Ritchie
Noam Aigerman
Many network architectures exist for learning on meshes, yet their constructions entail delicate trade-offs between difficulty learning high… (see more)-frequency features, insufficient receptive field, sensitivity to discretization, and inefficient computational overhead. Drawing from classic local-global approaches in mesh processing, we introduce PoissonNet, a novel neural architecture that overcomes all of these deficiencies by formulating a local-global learning scheme, which uses Poisson's equation as the primary mechanism for feature propagation. Our core network block is simple; we apply learned local feature transformations in the gradient domain of the mesh, then solve a Poisson system to propagate scalar feature updates across the surface globally. Our local-global learning framework preserves the features's full frequency spectrum and provides a truly global receptive field, while remaining agnostic to mesh triangulation. Our construction is efficient, requiring far less compute overhead than comparable methods, which enables scalability -- both in the size of our datasets, and the size of individual training samples. These qualities are validated on various experiments where, compared to previous intrinsic architectures, we attain state-of-the-art performance on semantic segmentation and parameterizing highly-detailed animated surfaces. Finally, as a central application of PoissonNet, we show its ability to learn deformations, significantly outperforming state-of-the-art architectures that learn on surfaces.
2025-10-14
ArXiv (preprint)
doi.org
arxiv.org
Reframing AI-for-Good: Radical Questioning in AI for Human Trafficking Interventions
Pratheeksha Nair
Gabriel Lefebvre
Maryam Molamohammadi
Sophia Garrel
Reihaneh Rabbany
This paper introduces Radical Questioning (RQ), a structured, pre-design ethics framework developed to assess whether artificial intelligenc… (see more)e (AI) should be applied to complex social problems rather than merely how. While much of responsible AI development focuses on aligning systems with principles such as fairness, transparency, and accountability, it often begins after the decision to build has already been made, implicitly treating the deployment of AI as a given rather than a question in itself. In domains such as human trafficking, marked by contested definitions, systemic injustice, and deep stakeholder asymmetries, such assumptions can obscure foundational ethical concerns. RQ offers an upstream, deliberative process for surfacing these concerns before design begins. Drawing from critical theory, participatory ethics, and relational responsibility, RQ formalizes a five-step framework to interrogate problem framings, confront techno-solutionist tendencies, and reflect on the moral legitimacy of intervention. Developed through interdisciplinary collaboration and engagement with survivor-led organizations, RQ was piloted in the domain of human trafficking (HT) which is a particularly high-stakes and ethically entangled application area. Its use led to a fundamental design shift: away from automated detection tools and toward survivor-controlled, empowerment-based technologies. We argue that RQ's novelty lies in both its temporal position, i.e, prior to technical design, and its orientation toward domains where harm is structural and ethical clarity cannot be achieved through one-size-fits-all solutions. RQ thus addresses a critical gap between abstract principles of responsible AI and the lived ethical demands of real-world deployment.
2025-10-14
Proceedings of the AAAI/ACM Conference on AI, Ethics, and Society (published)
doi.org
Simplicial Embeddings Improve Sample Efficiency in Actor-Critic Agents
Johan Samir Obando Ceron
Walter Mayor
Samuel Lavoie
Scott Fujimoto
Aaron Courville
Pablo Samuel Castro
Recent works have proposed accelerating the wall-clock training time of actor-critic methods via the use of large-scale environment parallel… (see more)ization; unfortunately, these can sometimes still require large number of environment interactions to achieve a desired level of performance. Noting that well-structured representations can improve the generalization and sample efficiency of deep reinforcement learning (RL) agents, we propose the use of simplicial embeddings: lightweight representation layers that constrain embeddings to simplicial structures. This geometric inductive bias results in sparse and discrete features that stabilize critic bootstrapping and strengthen policy gradients. When applied to FastTD3, FastSAC, and PPO, simplicial embeddings consistently improve sample efficiency and final performance across a variety of continuous- and discrete-control environments, without any loss in runtime speed.
2025-10-14
ArXiv (preprint)
doi.org
arxiv.org
The Interpolation Constraint in the RV Analysis of M-Dwarfs Using Empirical Templates
Dhvani Doshi
Nicolas B. Cowan
E. Artigau
René Doyon
André M. Silva
Khaled Al Moulla
Yashar Hezaveh
Precise radial velocity (pRV) measurements of M-dwarfs in the near-infrared (NIR) rely on empirical templates due to the lack of accurate st… (see more)ellar spectral models in this regime. Templates are assumed to approximate the true spectrum when constructed from many observations or in the high signal-to-noise limit. We develop a numerical simulation that generates SPIRou-like pRV observations from PHOENIX spectra, constructs empirical templates, and estimates radial velocities. This simulation solely considers photon noise and evaluates when empirical templates remain reliable for pRV analysis. Our results reveal a previously unrecognized noise source in templates, establishing a fundamental floor for template-based pRV measurements. We find that templates inherently include distortions in stellar line shapes due to imperfect interpolation at the detector's sampling resolution. The magnitude of this interpolation error depends on sampling resolution and RV content. Consequently, while stars with a higher RV content, such as cooler M-dwarfs are expected to yield lower RV uncertainties, their dense spectral features can amplify interpolation errors, potentially biasing RV estimates. For a typical M4V star, SPIRou's spectral and sampling resolution imposes an RV uncertainty floor of 0.5-0.8 m/s, independent of the star's magnitude or the telescope's aperture. These findings reveal a limitation of template-based pRV methods, underscoring the need for improved spectral modeling and better-than-Nyquist detector sampling to reach the next level of RV precision.
2025-10-14
The Astronomical Journal (published)
doi.org
arxiv.org
Joint Satellite Power Consumption and Handover Optimization for LEO Constellations
Yassine Afif
Mohammed Almekhlafi
Antoine Lesage-Landry
Gunes Karabulut Kurt
In satellite constellation-based communication systems, continuous user coverage requires frequent handoffs due to the dynamic topology indu… (see more)ced by the Low Earth Orbit (LEO) satellites. Each handoff between a satellite and ground users introduces additional signaling and power consumption, which can become a significant burden as the size of the constellation continues to increase. This work focuses on the optimization of the total transmission rate in a LEO-to-user system, by jointly considering the total transmitted power, user-satellite associations, and power consumption, the latter being handled through a penalty on handoff events. We consider a system where LEO satellites serve users located in remote areas with no terrestrial connectivity, and formulate the power allocation problem as a mixed-integer concave linear program (MICP) subject to power and association constraints. Our approach can be solved with off-the-shelf solvers and is benchmarked against a naive baseline where users associate to their closest visible satellite. Extensive Monte Carlo simulations demonstrate the effectiveness of the proposed method in controlling the handoff frequency while maintaining high user throughput. These performance gains highlight the effectiveness of our handover-aware optimization strategy, which ensures that user rates improve significantly, by about 40%, without incurring a disproportionate rise in the handoff frequency.
2025-10-13
International Conference on Wireless for Space and Extreme Environments (published)
doi.org
arxiv.org
Personalized Federated Fine-Tuning of Vision Foundation Models for Healthcare
Adam Tupper
Christian Gagné
2025-10-13
ArXiv (preprint)
doi.org
arxiv.org
RNAGenScape: Property-guided Optimization and Interpolation of mRNA Sequences with Manifold Langevin Dynamics
Danqi Liao
Chen Liu
Xingzhi Sun
Di'e Tang
Haochen Wang
Scott E. Youlten
Srikar Krishna Gopinath
Haejeong Lee
Ethan C. Strayer
Antonio J. Giraldez
Smita Krishnaswamy
2025-10-13
ArXiv (preprint)
doi.org
arxiv.org
Sensory multi-brain stimulation enhances dyadic cooperative behavior
Ivo Leiva-Cisterna
Paulo Barraza
Eugenio Rodríguez
Guillaume Dumas
Hyperscanning research suggests that interbrain synchronization supports the regulation of social behavior. However, the evidence is predomi… (see more)nantly correlational, leaving a gap for epiphenomenal accounts, where synchrony merely represents concurrent stimulus processing rather than a mechanism relevant to interpersonal interactions. Here, we demonstrate that interbrain synchrony causally drives cooperative success, as evidenced by non-invasive stimulation enhancing coupling and subsequently improving performance in a concurrent interdependent cooperation task. We applied dual-sensory entrainment at 16 Hz and 40 Hz to dyads and compared their performance with non-entrained control dyads performing the same cooperation task. We found that dual stimulation improved interbrain synchrony at the targeted frequencies relative to controls, with 16 Hz entrainment producing the most prominent effect. Strikingly, sensory entrainment facilitated sustained behavioral coupling, allowing partners to maintain coordination over extended periods. Notably, these effects are contingent on improved response coordination, indicating the importance of interbrain coupling for facilitating coordination and demonstrating causally that partner neural attunement is necessary to produce effective joint behavior. Thus, our study supports the concept that interbrain synchrony represents a neural mechanism with functional specificity in social interactions.
2025-10-13
Social Cognitive and Affective Neuroscience (published)
doi.org
TimelyGPT: Extrapolatable Transformer Pre-training for Long-term Time-Series Forecasting in Healthcare
Ziyang Song
Qincheng Lu
Hao Xu
He Zhu
David L. Buckeridge
Yue Li
Large-scale pre-trained models (PTMs) such as BERT and GPT have recently achieved great success in Natural Language Processing and Computer … (see more)Vision domains. However, the development of PTMs on healthcare time-series data is lagging behind.This underscores the limitations of the existing transformer-based architectures, particularly their scalability to handle large-scale time series and ability to capture long-term temporal dependencies. In this study, we present Timely Generative Pre-trained Transformer (TimelyGPT). TimelyGPT employs an extrapolatable position (xPos) embedding to encode trend and periodic patterns into time-series representations. It also integrates recurrent attention and temporal convolution modules to effectively capture global-local temporal dependencies. We evaluated TimelyGPT on two large-scale healthcare time series datasets corresponding to continuous biosignals and irregularly-sampled time series, respectively. Our experiments show that during pre-training, TimelyGPT excels in learning time-series representations from continuously monitored biosignals and irregularly-sampled time series data commonly observed in longitudinal electronic health records (EHRs). In forecasting continuous biosignals, TimelyGPT achieves accurate extrapolation up to 6,000 timesteps of body temperature during the sleep stage transition, given a short look-up window (i.e., prompt) containing only 2,000 timesteps. For irregularly-sampled time series, TimelyGPT with a proposed time-specific inference demonstrates high top recall scores in predicting future diagnoses using early diagnostic records, effectively handling irregular intervals between clinical records. Together, we envision TimelyGPT to be useful in a broad spectrum of health domains, including long-term patient health state forecasting and patient risk trajectory prediction.
2025-10-13
Health Information Science and Systems (published)
doi.org
arxiv.org
Disease-Specific Prediction of Missense Variant Pathogenicity with DNA Language Models and Graph Neural Networks
Mohamed Ghadie
Sameer Sardaar
Yannis Trakadis
2025-10-12
Bioengineering (published)
doi.org