Evaluating White Matter Lesion Segmentations with Refined Sørensen-Dice Analysis
Aaron Carass
Snehashis Roy
Adrian Gherman
Jacob C. Reinhold
Andrew Jesson
Oskar Maier
Heinz Handels
Mohsen Ghafoorian
Bram Platel
Ariel Birenbaum
Hayit Greenspan
Dzung L. Pham
Ciprian M. Crainiceanu
Peter A. Calabresi
Jerry L. Prince
William R. Gray Roncal
Russell T. Shinohara
Ipek Oguz
An Analysis of the Adaptation Speed of Causal Models
Rémi LE PRIOL
Reza Babanezhad Harikandeh
We consider the problem of discovering the causal process that generated a collection of datasets. We assume that all these datasets were ge… (see more)nerated by unknown sparse interventions on a structural causal model (SCM)
COVI White Paper
Hannah Alsdurf
Tristan Deleu
Prateek Gupta
Daphne Ippolito
Richard Janda
Max Jarvie
Tyler J. Kolody
Sekoul Krastev
Robert Obryk
Dan Pilat
Valerie Pisano
Benjamin Prud'homme
Meng Qu
Nasim Rahaman
Jean-franois Rousseau
Abhinav Sharma
Brooke Struck … (see 3 more)
Martin Weiss
Yun William Yu
The SARS-CoV-2 (Covid-19) pandemic has caused significant strain on public health institutions around the world. Contact tracing is an essen… (see more)tial tool to change the course of the Covid-19 pandemic. Manual contact tracing of Covid-19 cases has significant challenges that limit the ability of public health authorities to minimize community infections. Personalized peer-to-peer contact tracing through the use of mobile apps has the potential to shift the paradigm. Some countries have deployed centralized tracking systems, but more privacy-protecting decentralized systems offer much of the same benefit without concentrating data in the hands of a state authority or for-profit corporations. Machine learning methods can circumvent some of the limitations of standard digital tracing by incorporating many clues and their uncertainty into a more graded and precise estimation of infection risk. The estimated risk can provide early risk awareness, personalized recommendations and relevant information to the user. Finally, non-identifying risk data can inform epidemiological models trained jointly with the machine learning predictor. These models can provide statistical evidence for the importance of factors involved in disease transmission. They can also be used to monitor, evaluate and optimize health policy and (de)confinement scenarios according to medical and economic productivity indicators. However, such a strategy based on mobile apps and machine learning should proactively mitigate potential ethical and privacy risks, which could have substantial impacts on society (not only impacts on health but also impacts such as stigmatization and abuse of personal data). Here, we present an overview of the rationale, design, ethical considerations and privacy strategy of `COVI,' a Covid-19 public peer-to-peer contact tracing and risk awareness mobile application developed in Canada.
COVI White Paper
Hannah Alsdurf
Tristan Deleu
Prateek Gupta
Daphne Ippolito
Richard Janda
Max Jarvie
Tyler J. Kolody
Sekoul Krastev
Robert Obryk
Dan Pilat
Valerie Pisano
Benjamin Prud'homme
Meng Qu
Nasim Rahaman
Jean-franois Rousseau
Abhinav Sharma
Brooke Struck … (see 3 more)
Martin Weiss
Yun William Yu
COVI White Paper
Hannah Alsdurf
Tristan Deleu
Prateek Gupta
Daphne Ippolito
Richard Janda
Max Jarvie
Tyler J. Kolody
Sekoul Krastev
Robert Obryk
Dan Pilat
Valerie Pisano
Benjamin Prud'homme
Meng Qu
Nasim Rahaman
Jean-franois Rousseau
Abhinav Sharma
Brooke Struck … (see 3 more)
Martin Weiss
Yun William Yu
Graph Density-Aware Losses for Novel Compositions in Scene Graph Generation
Boris Knyazev
Harm de Vries
Cătălina Cangea
Graham W. Taylor
Story Forest
Fred X. Han
Di Niu
Linglong Kong
Kunfeng Lai
Yu Xu
Extracting events accurately from vast news corpora and organize events logically is critical for news apps and search engines, which aim to… (see more) organize news information collected from the Internet and present it to users in the most sensible forms. Intuitively speaking, an event is a group of news documents that report the same news incident possibly in different ways. In this article, we describe our experience of implementing a news content organization system at Tencent to discover events from vast streams of breaking news and to evolve news story structures in an online fashion. Our real-world system faces unique challenges in contrast to previous studies on topic detection and tracking (TDT) and event timeline or graph generation, in that we (1) need to accurately and quickly extract distinguishable events from massive streams of long text documents, and (2) must develop the structures of event stories in an online manner, in order to guarantee a consistent user viewing experience. In solving these challenges, we propose Story Forest, a set of online schemes that automatically clusters streaming documents into events, while connecting related events in growing trees to tell evolving stories. A core novelty of our Story Forest system is EventX, a semi-supervised scheme to extract events from massive Internet news corpora. EventX relies on a two-layered, graph-based clustering procedure to group documents into fine-grained events. We conducted extensive evaluations based on (1) 60 GB of real-world Chinese news data, (2) a large Chinese Internet news dataset that contains 11,748 news articles with truth event labels, and (3) the 20 News Groups English dataset, through detailed pilot user experience studies. The results demonstrate the superior capabilities of Story Forest to accurately identify events and organize news text into a logical structure that is appealing to human readers.
Active Domain Randomization
Bhairav Mehta
Manfred Diaz
Florian Golemo
Domain randomization is a popular technique for improving domain transfer, often used in a zero-shot setting when the target domain is unkno… (see more)wn or cannot easily be used for training. In this work, we empirically examine the effects of domain randomization on agent generalization. Our experiments show that domain randomization may lead to suboptimal, high-variance policies, which we attribute to the uniform sampling of environment parameters. We propose Active Domain Randomization, a novel algorithm that learns a parameter sampling strategy. Our method looks for the most informative environment variations within the given randomization ranges by leveraging the discrepancies of policy rollouts in randomized and reference environment instances. We find that training more frequently on these instances leads to better overall agent generalization. In addition, when domain randomization and policy transfer fail, Active Domain Randomization offers more insight into the deficiencies of both the chosen parameter ranges and the learned policy, allowing for more focused debugging. Our experiments across various physics-based simulated and a real-robot task show that this enhancement leads to more robust, consistent policies.
Leveraging exploration in off-policy algorithms via normalizing flows
Exploration is a crucial component for discovering approximately optimal policies in most high-dimensional reinforcement learning (RL) setti… (see more)ngs with sparse rewards. Approaches such as neural density models and continuous exploration (e.g., Go-Explore) have been instrumental in recent advances. Soft actor-critic (SAC) is a method for improving exploration that aims to combine off-policy updates while maximizing the policy entropy. We extend SAC to a richer class of probability distributions through normalizing flows, which we show improves performance in exploration, sample complexity, and convergence. Finally, we show that not only the normalizing flow policy outperforms SAC on MuJoCo domains, it is also significantly lighter, using as low as 5.6% of the original network's parameters for similar performance.
Differential neural circuitry behind autism subtypes with imbalanced social-communicative and restricted repetitive behavior symptoms
Natasha Bertelsen
Isotta Landi
Richard A.I. Bethlehem
Jakob Seidlitz
Elena Maria Busuoli
Veronica Mandelli
Eleonora Satta
Stavros Trakoshis
Bonnie Auyeung
Prantik Kundu
Eva Loth
Sarah Baumeister
Christian Beckmann
Sven Bölte
Thomas Bourgeron
Tony Charman
Sarah Durston
Christine Ecker
Rosemary Holt … (see 15 more)
Mark Johnson
Emily J. H. Jones
Luke Mason
Andreas Meyer-Lindenberg
Carolin Moessnang
Marianne Oldehinkel
Antonio Persico
Julian Tillmann
Steven C. R. Williams
Will Spooren
Declan Murphy
Jan K. Buitelaar
Simon Baron-Cohen
Meng-Chuan Lai
Michael V. Lombardo
Social-communication (SC) and restricted repetitive behaviors (RRB) are autism diagnostic symptom domains. SC and RRB severity can markedly … (see more)differ within and between individuals and may be underpinned by different neural circuitry and genetic mechanisms. Modeling SC-RRB balance could help identify how neural circuitry and genetic mechanisms map onto such phenotypic heterogeneity. Here we developed a phenotypic stratification model that makes highly accurate (97-99%) out-of-sample SC=RRB, SC>RRB, and RRB>SC subtype predictions. Applying this model to resting state fMRI data from the EU-AIMS LEAP dataset (n=509), we find that while the phenotypic subtypes share many commonalities in terms of intrinsic functional connectivity, they also show subtype-specific qualitative differences compared to a typically-developing group (TD). Specifically, the somatomotor network is hypoconnected with perisylvian circuitry in SC>RRB and visual association circuitry in SC=RRB. The SC=RRB subtype also showed hyperconnectivity between medial motor and anterior salience circuitry. Genes that are highly expressed within these subtype-specific networks show a differential enrichment pattern with known ASD associated genes, indicating that such circuits are affected by differing autism-associated genomic mechanisms. These results suggest that SC-RRB imbalance subtypes share some commonalities but also express subtle differences in functional neural circuitry and the genomic underpinnings behind such circuitry.
An Empirical Study of Human Behavioral Agents in Bandits, Contextual Bandits and Reinforcement Learning.
Baihan Lin
Guillermo Cecchi
Djallel Bouneffouf
Jenna Reinen
Artificial behavioral agents are often evaluated based on their consistent behaviors and performance to take sequential actions in an enviro… (see more)nment to maximize some notion of cumulative reward. However, human decision making in real life usually involves different strategies and behavioral trajectories that lead to the same empirical outcome. Motivated by clinical literature of a wide range of neurological and psychiatric disorders, we propose here a more general and flexible parametric framework for sequential decision making that involves a two-stream reward processing mechanism. We demonstrated that this framework is flexible and unified enough to incorporate a family of problems spanning multi-armed bandits (MAB), contextual bandits (CB) and reinforcement learning (RL), which decompose the sequential decision making process in different levels. Inspired by the known reward processing abnormalities of many mental disorders, our clinically-inspired agents demonstrated interesting behavioral trajectories and comparable performance on simulated tasks with particular reward distributions, a real-world dataset capturing human decision-making in gambling tasks, and the PacMan game across different reward stationarities in a lifelong learning setting.
Unified Models of Human Behavioral Agents in Bandits, Contextual Bandits and RL
Baihan Lin
Guillermo Cecchi
Djallel Bouneffouf
Jenna Reinen