Portrait of Marco Bonizzato

Marco Bonizzato

Associate Academic Member
Assistant Professor, Polytechnique Montréal, Department of Electrical Engineering
Adjunct Professor, Université de Montréal, Department of Neurosciences
Research Topics
Blackbox Optimization
Computational Neuroscience
Dynamical Systems

Biography

Marco Bonizzato is a control, electrical and life sciences engineer with over ten years’ experience in implantable brain-computer interfaces and neuromodulation technology. He has unique double expertise in (a) neural prostheses, and (b) machine intelligence and optimization.

Bonizzato is an assistant professor of electrical engineering at Polytechnique Montréal and an adjunct professor of neuroscience at Université de Montréal.

He also directs the Polytechnique’s sciNeurotech Lab, whose research goal is to develop the entire translational arc of new neurostimulation therapies aimed at restoring sensorimotor function after neurotrauma—from discovery in rodents to application in human medical technologies tailored and personalized to the user using AI.

Current Students

PhD - Polytechnique Montréal
Master's Research - Polytechnique Montréal
Co-supervisor :
PhD - Université de Montréal
Master's Research - Polytechnique Montréal
Master's Research - Université de Montréal
Postdoctorate - Polytechnique Montréal

Publications

Hallucination Detox: Sensitive Neuron Dropout (SeND) for Large Language Model Training
Shahrad Mohammadzadeh
Juan David Guerra
As large language models (LLMs) become increasingly deployed across various industries, concerns regarding their reliability, particularly d… (see more)ue to hallucinations-outputs that are factually inaccurate or irrelevant to user input-have grown. Our research investigates the relationship between the training process and the emergence of hallucinations to address a key gap in existing research that focuses primarily on post hoc detection and mitigation strategies. Using models from the Pythia suite (70M-12B parameters) and several hallucination detection metrics, we analyze hallucination trends throughout training and explore LLM internal dynamics. We introduce SEnsitive Neuron Dropout (SeND), a novel training protocol designed to mitigate hallucinations by reducing variance during training. SeND achieves this by deterministically dropping neurons with significant variability on a dataset, referred to as Sensitive Neurons. In addition, we develop an unsupervised hallucination detection metric, Efficient EigenScore (EES), which approximates the traditional EigenScore in 2x speed. This efficient metric is integrated into our protocol, allowing SeND to be both computationally scalable and effective at reducing hallucinations. Our empirical evaluation demonstrates that our approach improves LLM reliability at test time by up to 40% compared to normal training while also providing an efficient method to improve factual accuracy when adapting LLMs to domains such as Wikipedia and Medical datasets.
Gaussian-process-based Bayesian optimization for neurostimulation interventions in rats
Léo Choinière
Rose Guay-Hottin
Rémi Picard
Numa Dancause
Invasive Brain Computer Interface for Motor Restoration in Spinal Cord Injury: A Systematic Review.
Jordan J. Levett
Lior M. Elkaim
Farbod Niazi
Michael H. Weber
Christian Iorio-Morin
Alexander G. Weil
Autonomous optimization of neuroprosthetic stimulation parameters that drive the motor cortex and spinal cord outputs in rats and monkeys
Rose Guay Hottin
Sandrine L. Côté
Elena Massai
Léo Choinière
Uzay Macar
Samuel Laferrière
Parikshat Sirpal
Stephan Quessy
Marina Martinez
Numa Dancause
Use of Invasive Brain-Computer Interfaces in Pediatric Neurosurgery: Technical and Ethical Considerations
David Bergeron
Christian Iorio-Morin
Nathalie Orr Gaucher
Éric Racine
Alexander G. Weil
Implementing automation in deep brain stimulation: has the time come?
Alfonso Fasano