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Publications
Step-GRAND: A Low Latency Universal Soft-Input Decoder
Syed Mohsin Abbas
Marwan Jalaleddine
Chi-Ying Tsui
Warren J. Gross
GRAND features both soft-input and hard-input variants that are well suited to efficient hardware implementations that can be characterized … (see more)with achievable average and worst-case decoding latency. This paper introduces step-GRAND, a soft-input variant of GRAND that, in addition to achieving appealing average decoding latency, also reduces the worst-case decoding latency of the corresponding hardware implementation. The hardware implementation results demonstrate that the proposed step-GRAND can decode CA-polar code (128,105+11) with an average information throughput of 47.7 Gbps at the target FER of
Automatic Head and Neck Tumor segmentation and outcome prediction relying on FDG-PET/CT images: Findings from the second edition of the HECKTOR challenge
Augmenting pretrained language models with retrievers to select the supporting documents has shown promise in effectively solving common NLP… (see more) problems, including language modeling and question answering, in an interpretable way. In this paper, we first study the strengths and weaknesses of different retriever-augmented language models (REALM,
2023-11-30
Findings of the Association for Computational Linguistics: EMNLP 2023 (published)
We uncovered IPs of AD susceptibility differently expressed in male and female probands and affected by the diagnosed parent’s sex. Matern… (see more)al inheritance highlighted memory performance in both sexes, whereas paternal inheritance was particularly linked to cardiovascular health in males. The inheritance of the IPs was reflected in the brain structure at both superficial and deeper layers of the cortex. As the first study of its kind, our cross‐generational analysis of matri‐ vs. patrilinear AD risk bridges the epidemiological and clinical literature by leveraging the power of ∼1,000 patient visits. Our completely data‐driven framework ultimately dissociated phenotypes of maternal and paternal AD risk single‐handedly expressed in male and female probands.
From physics to sentience: Deciphering the semantics of the free-energy principle and evaluating its claims: Comment on "Path integrals, particular kinds, and strange things" by Karl Friston et al.
Studies combining metabolomics and genetics, known as metabolite genome-wide association studies (mGWAS), have provided valuable insights in… (see more)to our understanding of the genetic control of metabolite levels. However, the biological interpretation of these associations remains challenging due to a lack of existing tools to annotate mGWAS gene-metabolite pairs beyond the use of conservative statistical significance threshold. Here, we computed the shortest reactional distance (SRD) based on the curated knowledge of the KEGG database to explore its utility in enhancing the biological interpretation of results from three independent mGWAS, including a case study on sickle cell disease patients. Results show that, in reported mGWAS pairs, there is an excess of small SRD values and that SRD values and p-values significantly correlate, even beyond the standard conservative thresholds. The added-value of SRD annotation is shown for identification of potential false negative hits, exemplified by the finding of gene-metabolite associations with SRD ≤1 that did not reach standard genome-wide significance cut-off. The wider use of this statistic as an mGWAS annotation would prevent the exclusion of biologically relevant associations and can also identify errors or gaps in current metabolic pathway databases. Our findings highlight the SRD metric as an objective, quantitative and easy-to-compute annotation for gene-metabolite pairs that can be used to integrate statistical evidence to biological networks.