Publications

Neighbor-Aware Calibration of Segmentation Networks with Penalty-Based Constraints
Balamurali Murugesan
Bingyuan Liu
Ismail Ben Ayed
Jose Dolz
Ensuring reliable confidence scores from deep neural networks is of paramount significance in critical decision-making systems, particularly… (see more) in real-world domains such as healthcare. Recent literature on calibrating deep segmentation networks has resulted in substantial progress. Nevertheless, these approaches are strongly inspired by the advancements in classification tasks, and thus their uncertainty is usually modeled by leveraging the information of individual pixels, disregarding the local structure of the object of interest. Indeed, only the recent Spatially Varying Label Smoothing (SVLS) approach considers pixel spatial relationships across classes, by softening the pixel label assignments with a discrete spatial Gaussian kernel. In this work, we first present a constrained optimization perspective of SVLS and demonstrate that it enforces an implicit constraint on soft class proportions of surrounding pixels. Furthermore, our analysis shows that SVLS lacks a mechanism to balance the contribution of the constraint with the primary objective, potentially hindering the optimization process. Based on these observations, we propose NACL (Neighbor Aware CaLibration), a principled and simple solution based on equality constraints on the logit values, which enables to control explicitly both the enforced constraint and the weight of the penalty, offering more flexibility. Comprehensive experiments on a wide variety of well-known segmentation benchmarks demonstrate the superior calibration performance of the proposed approach, without affecting its discriminative power. Furthermore, ablation studies empirically show the model agnostic nature of our approach, which can be used to train a wide span of deep segmentation networks.
Marc Bellemare
Bellemare Marc-Emmanuel
Beyond Predictive Algorithms in Child Welfare
Erina Seh-Young Moon
Erin Moon
Devansh Saxena
Shion Guha
Connectome-based reservoir computing with the conn2res toolbox
Laura E. Suárez
Agoston Mihalik
Filip Milisav
Kenji Marshall
Petra E. Vértes
Bratislav Misic
Brain connectivity patterns shape computational capacity of biological neural networks, however mapping empirically measured connectivity to… (see more) artificial networks remains challenging. The authors present a toolbox for implementing biological neural networks as artificial reservoir networks. The toolbox allows for a variety of empirical/measured connectomes and is equipped with various dynamical systems, and cognitive tasks. The connection patterns of neural circuits form a complex network. How signaling in these circuits manifests as complex cognition and adaptive behaviour remains the central question in neuroscience. Concomitant advances in connectomics and artificial intelligence open fundamentally new opportunities to understand how connection patterns shape computational capacity in biological brain networks. Reservoir computing is a versatile paradigm that uses high-dimensional, nonlinear dynamical systems to perform computations and approximate cognitive functions. Here we present conn2res : an open-source Python toolbox for implementing biological neural networks as artificial neural networks. conn2res is modular, allowing arbitrary network architecture and dynamics to be imposed. The toolbox allows researchers to input connectomes reconstructed using multiple techniques, from tract tracing to noninvasive diffusion imaging, and to impose multiple dynamical systems, from spiking neurons to memristive dynamics. The versatility of the conn2res toolbox allows us to ask new questions at the confluence of neuroscience and artificial intelligence. By reconceptualizing function as computation, conn2res sets the stage for a more mechanistic understanding of structure-function relationships in brain networks.
Multi-variable Hard Physical Constraints for Climate Model Downscaling
Global Climate Models (GCMs) are the primary tool to simulate climate evolution and assess the impacts of climate change. However, they ofte… (see more)n operate at a coarse spatial resolution that limits their accuracy in reproducing local-scale phenomena. Statistical downscaling methods leveraging deep learning offer a solution to this problem by approximating local-scale climate fields from coarse variables, thus enabling regional GCM projections. Typically, climate fields of different variables of interest are downscaled independently, resulting in violations of fundamental physical properties across interconnected variables. This study investigates the scope of this problem and, through an application on temperature, lays the foundation for a framework introducing multi-variable hard constraints that guarantees physical relationships between groups of downscaled climate variables.
RapidBrachyTG43: A Geant4‐based TG‐43 parameter and dose calculation module for brachytherapy dosimetry
Jonathan Kalinowski
S. Enger
Transnational conservation to anticipate future plant shifts in Europe
Yohann Chauvier-Mendes
Peter H. Verburg
Dirk N. Karger
Loïc Pellissier
Sébastien Lavergne
Niklaus E. Zimmermann
Wilfried Thuiller
Deployable Reinforcement Learning with Variable Control Rate
Yong Wang
METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII
Burak Kocak
Tugba Akinci D’Antonoli
Nathaniel Mercaldo
Angel Alberich-Bayarri
Bettina Baessler
Ilaria Ambrosini
Anna E. Andreychenko
Spyridon Bakas
Regina G. H. Beets-Tan
Keno Bressem
Irene Buvat
Roberto Cannella
Luca Alessandro Cappellini
Armando Ugo Cavallo
Leonid L. Chepelev
Linda Chi Hang Chu
Aydin Demircioglu
Nandita M. deSouza
Matthias Dietzel
Salvatore Claudio Fanni … (see 40 more)
Andrey Fedorov
Laure S. Fournier
Valentina Giannini
Rossano Girometti
Kevin B. W. Groot Lipman
Georgios Kalarakis
Brendan S. Kelly
Michail E. Klontzas
Dow-Mu Koh
Elmar Kotter
Ho Yun Lee
Mario Maas
Luis Marti-Bonmati
Henning Müller
Nancy Obuchowski
Fanny Orlhac
Nikolaos Papanikolaou
Ekaterina Petrash
Elisabeth Pfaehler
Daniel Pinto dos Santos
Andrea Ponsiglione
Sebastià Sabater
Francesco Sardanelli
Philipp Seeböck
Nanna M. Sijtsema
Arnaldo Stanzione
Alberto Traverso
Lorenzo Ugga
Lisanne V. van Dijk
Joost J. M. van Griethuysen
Robbert W. van Hamersvelt
Peter van Ooijen
Federica Vernuccio
Alan Wang
Stuart Williams
Jan Witowski
Zhongyi Zhang
Alex Zwanenburg
Renato Cuocolo
Abstract B049: Pancreatic beta cell stress pathways drive pancreatic ductal adenocarcinoma development in obesity
Cathy C. Garcia
Aarthi Venkat
Sherry Agabiti
Lauren Lawres
Rebecca Cardone
Richard G. Kibbey
Mandar Deepak Muzumdar
Amortizing Intractable Inference in Large Language Models
Autoregressive large language models (LLMs) compress knowledge from their training data through next-token conditional distributions. This l… (see more)imits tractable querying of this knowledge to start-to-end autoregressive sampling. However, many tasks of interest -- including sequence continuation, infilling, and other forms of constrained generation -- involve sampling from intractable posterior distributions. We address this limitation by using amortized Bayesian inference to sample from these intractable posteriors. Such amortization is algorithmically achieved by fine-tuning LLMs via diversity-seeking reinforcement learning algorithms: generative flow networks (GFlowNets). We empirically demonstrate that this distribution-matching paradigm of LLM fine-tuning can serve as an effective alternative to maximum-likelihood training and reward-maximizing policy optimization. As an important application, we interpret chain-of-thought reasoning as a latent variable modeling problem and demonstrate that our approach enables data-efficient adaptation of LLMs to tasks that require multi-step rationalization and tool use.
Balancing Act: Constraining Disparate Impact in Sparse Models
Model pruning is a popular approach to enable the deployment of large deep learning models on edge devices with restricted computational or … (see more)storage capacities. Although sparse models achieve performance comparable to that of their dense counterparts at the level of the entire dataset, they exhibit high accuracy drops for some data sub-groups. Existing methods to mitigate this disparate impact induced by pruning (i) rely on surrogate metrics that address the problem indirectly and have limited interpretability; or (ii) scale poorly with the number of protected sub-groups in terms of computational cost. We propose a constrained optimization approach that directly addresses the disparate impact of pruning: our formulation bounds the accuracy change between the dense and sparse models, for each sub-group. This choice of constraints provides an interpretable success criterion to determine if a pruned model achieves acceptable disparity levels. Experimental results demonstrate that our technique scales reliably to problems involving large models and hundreds of protected sub-groups.