NLP in the era of generative AI, cognitive sciences, and societal transformation
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This program is designed to provide decision-makers, policymakers and professional working in policy with a foundational understanding of AI technology.
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Publications
Intra-Host Evolution Analyses in an Immunosuppressed Patient Supports SARS-CoV-2 Viral Reservoir Hypothesis
Real-world decision-making problems involve Type 1 decision-dependent uncertainty, where the probability distribution of the stochastic proc… (see more)ess depends on the model decisions. However, few studies focus on two-stage stochastic programs with this type of endogenous uncertainty, and those that do lack general methodologies. We thus propose herein a general method for solving a class of these programs based on the transformation of random variables, a technique widely employed in probability and statistics. The proposed method is tailored to large-scale problems with discrete or continuous endogenous random variables. The random variable transformation allows the use of the sample average approximation (SAA) method, which provides optimality convergence guarantees under certain conditions. We show that, for some classical distributions, the proposed method reduces to solving mixed-integer linear or convex programs. Finally, we validate this method by applying it to a network design and facility-protection problem, considering distinct decision-dependent distributions for the random variables. Whereas most distributions result in a nonlinear nonconvex deterministic equivalent program, the proposed method solves mixed-integer linear programs in all cases. In addition, it produces attractive performance estimators for the SAA method in a reasonable computational time and outperforms the case in which the endogenous distribution defines a mixed-integer deterministic equivalent.
Hi-C is one of the most widely used approaches to study three-dimensional genome conformations. Contacts captured by a Hi-C experiment are r… (see more)epresented in a contact frequency matrix. Due to the limited sequencing depth and other factors, Hi-C contact frequency matrices are only approximations of the true interaction frequencies and are further reported without any quantification of uncertainty. Hence, downstream analyses based on Hi-C contact maps (e.g., TAD and loop annotation) are themselves point estimations. Here, we present the Hi-C interaction frequency sampler (HiCSampler) that reliably infers the posterior distribution of the interaction frequency for a given Hi-C contact map by exploiting dependencies between neighboring loci. Posterior predictive checks demonstrate that HiCSampler can infer highly predictive chromosomal interaction frequency. Summary statistics calculated by HiCSampler provide a measurement of the uncertainty for Hi-C experiments, and samples inferred by HiCSampler are ready for use by most downstream analysis tools off the shelf and permit uncertainty measurements in these analyses without modifications.
While Transformers have enabled tremendous progress in various application settings, such architectures still lag behind traditional symboli… (see more)c planners for solving complex decision making tasks. In this work, we demonstrate how to train Transformers to solve complex planning tasks and present Searchformer, a Transformer model that optimally solves previously unseen Sokoban puzzles 93.7% of the time, while using up to 26.8% fewer search steps than standard
Human activity recognition (HAR) is a popular research field in computer vision that has already been widely studied. However, it is still a… (see more)n active research field since it plays an important role in many current and emerging real-world intelligent systems, like visual surveillance and human-computer interaction. Deep reinforcement learning (DRL) has recently been used to address the activity recognition problem with various purposes, such as finding attention in video data or obtaining the best network structure. DRL-based HAR has only been around for a short time, and it is a challenging, novel field of study. Therefore, to facilitate further research in this area, we have constructed a comprehensive survey on activity recognition methods that incorporate DRL. Throughout the article, we classify these methods according to their shared objectives and delve into how they are ingeniously framed within the DRL framework. As we navigate through the survey, we conclude by shedding light on the prominent challenges and lingering questions that await the attention of future researchers, paving the way for further advancements and breakthroughs in this exciting domain.
2024-02-19
IEEE Transactions on Neural Networks and Learning Systems (published)
Recent work has shown that deep reinforcement learning agents have difficulty in effectively using their network parameters. We leverage pri… (see more)or insights into the advantages of sparse training techniques and demonstrate that gradual magnitude pruning enables agents to maximize parameter effectiveness. This results in networks that yield dramatic performance improvements over traditional networks and exhibit a type of"scaling law", using only a small fraction of the full network parameters.