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Francis Carter

Alumni

Publications

Derivation and validation of indices incorporating vasopressor dose and blood pressure values over time
Alain Gervais
François Lamontagne
Jean-Baptiste Michaud
KJ Neill
Adhikari
Jean-Michel Pagé
Marie-Hélène Masse
Michael O Harhay
Michael Chassé
Félix Lamontagne
Katia Laforge
Alexandra Fortin
Marc-André Leclair
Simon Lévesque
Marie-Pier Domingue
Neda Momenzadeh
Martin Vallières
Ruxandra Pinto
Maxime Morin-Lavoie
Francis Carter … (see 2 more)
Félix Camirand Lemyre
MD MSc. François Lamontagne
Rationale The blood pressure value below which the benefits of vasopressors clearly outweigh their disadvantages is uncertain. Objectives Th… (see more)e main objective of this analysis was to investigate the statistical properties and potential utility of indices estimating the vasopressor dose-rates as a function of blood pressure values over time. Methods In this single-center observational study, we collected blood pressure values from intensive care unit (ICU) monitors and norepinephrine dose-rates from infusion pumps corresponding to a derivation and a validation cohort. Patients included in each cohort were 18 years or older and received norepinephrine in the ICU. We defined and derived indices corresponding to vasopressor therapy above (>65 mmHg) and below (60 mmHg) targets. We report the distribution of both indices over time from both cohorts as well as their associations with hospital mortal
2024-09-23
medRxiv (preprint)
doi.org
Derivation and validation of indices incorporating vasopressor dose and blood pressure values over time
Alain Gervais
François Lamontagne
Jean-Baptiste Michaud
KJ Neill
Adhikari
Jean-Michel Pagé
Marie-Hélène Masse
Michael O. Harhay
Michael Chassé
Félix Lamontagne
Katia Laforge
Alexandra Fortin
Marc-André Leclair
Simon Lévesque
Marie-Pier Domingue
Neda Momenzadeh
Martin Vallières
Ruxandra Pinto
Maxime Morin-Lavoie
Francis Carter … (see 2 more)
Félix Camirand Lemyre
MD MSc. François Lamontagne
Rationale The blood pressure value below which the benefits of vasopressors clearly outweigh their disadvantages is uncertain. Objectives Th… (see more)e main objective of this analysis was to investigate the statistical properties and potential utility of indices estimating the vasopressor dose-rates as a function of blood pressure values over time. Methods In this single-center observational study, we collected blood pressure values from intensive care unit (ICU) monitors and norepinephrine dose-rates from infusion pumps corresponding to a derivation and a validation cohort. Patients included in each cohort were 18 years or older and received norepinephrine in the ICU. We defined and derived indices corresponding to vasopressor therapy above (>65 mmHg) and below (60 mmHg) targets. We report the distribution of both indices over time from both cohorts as well as their associations with hospital mortal
2024-09-23
medRxiv (preprint)
doi.org