Publications

Interacting brains revisited: A cross‐brain network neuroscience perspective
Christian Gerloff
Kerstin Konrad
Danilo Bzdok
Christina Büsing
Vanessa Reindl
Elucidating the neural basis of social behavior is a long‐standing challenge in neuroscience. Such endeavors are driven by attempts to ext… (see more)end the isolated perspective on the human brain by considering interacting persons' brain activities, but a theoretical and computational framework for this purpose is still in its infancy. Here, we posit a comprehensive framework based on bipartite graphs for interbrain networks and address whether they provide meaningful insights into the neural underpinnings of social interactions. First, we show that the nodal density of such graphs exhibits nonrandom properties. While the current hyperscanning analyses mostly rely on global metrics, we encode the regions' roles via matrix decomposition to obtain an interpretable network representation yielding both global and local insights. With Bayesian modeling, we reveal how synchrony patterns seeded in specific brain regions contribute to global effects. Beyond inferential inquiries, we demonstrate that graph representations can be used to predict individual social characteristics, outperforming functional connectivity estimators for this purpose. In the future, this may provide a means of characterizing individual variations in social behavior or identifying biomarkers for social interaction and disorders.
2022-06-05
Human Brain Mapping (unknown)
doi.org
Technologically-assisted communication attenuates inter-brain synchrony
Linoy Schwartz
Jonathan Levy
Yaara Endevelt-Shapira
Amir Djalovski
Olga Hayut
Guillaume Dumas
Ruth Pinkenson Feldman
2022-06-05
NeuroImage (published)
doi.org
How Can Digital Mental Health Enhance Psychiatry?
Emilie Stern
Jean-Arthur MICOULAUD FRANCHI
Guillaume Dumas
Jeverson Moreira
Stephane Mouchabac
Julia Maruani
Pierre Philip
Michel Lejoyeux
Pierre A. GEOFFROY
The use of digital technologies is constantly growing around the world. The wider-spread adoption of digital technologies and solutions in t… (see more)he daily clinical practice in psychiatry seems to be a question of when, not if. We propose a synthesis of the scientific literature on digital technologies in psychiatry and discuss the main aspects of its possible uses and interests in psychiatry according to three domains of influence that appeared to us: 1) assist and improve current care: digital psychiatry allows for more people to have access to care by simply being more accessible but also by being less stigmatized and more convenient; 2) develop new treatments: digital psychiatry allows for new treatments to be distributed via apps, and practical guidelines can reduce ethical challenges and increase the efficacy of digital tools; and 3) produce scientific and medical knowledge: digital technologies offer larger and more objective data collection, allowing for more detection and prevention of symptoms. Finally, ethical and efficacy issues remain, and some guidelines have been put forth on how to safely use these solutions and prepare for the future.
2022-06-03
The Neuroscientist (published)
doi.org
Modeling electronic health record data using a knowledge-graph-embedded topic model
Yuesong Zou
Ahmad Pesaranghader
Aman Verma
David L Buckeridge
Yuemei Li
The rapid growth of electronic health record (EHR) datasets opens up promising opportunities to understand human diseases in a systematic wa… (see more)y. However, effective extraction of clinical knowledge from the EHR data has been hindered by its sparsity and noisy information. We present KG-ETM, an end-to-end knowledge graph-based multimodal embedded topic model. KG-ETM distills latent disease topics from EHR data by learning the embedding from the medical knowledge graphs. We applied KG-ETM to a large-scale EHR dataset consisting of over 1 million patients. We evaluated its performance based on EHR reconstruction and drug imputation. KG-ETM demonstrated superior performance over the alternative methods on both tasks. Moreover, our model learned clinically meaningful graph-informed embedding of the EHR codes. In additional, our model is also able to discover interpretable and accurate patient representations for patient stratification and drug recommendations.
2022-06-02
ArXiv (preprint)
doi.org
arxiv.org
Vendor-neutral sequences and fully transparent workflows improve inter-vendor reproducibility of quantitative MRI
Agah Karakuzu
Labonny Biswas
Julien Cohen-Adad
Nikola Stikov
We conclude that vendor-neutral workflows are feasible and compatible with clinical MRI scanners. The significant reduction of inter-vendor … (see more)variability using vendor-neutral sequences has important implications for qMRI research and for the reliability of multicenter clinical trials.
2022-06-02
Magnetic Resonance in Medicine (unknown)
doi.org
Expressiveness and Learnability: A Unifying View for Evaluating Self-Supervised Learning
Yuchen Lu
Zhen Liu
Aristide Baratin
Romain Laroche
Aaron Courville
Alessandro Sordoni
2022-06-01
ArXiv (preprint)
doi.org
openreview.net
Genetic correlates of phenotypic heterogeneity in autism
Varun Warrier
Xinhe Zhang
Patrick Reed
Alexandra Havdahl
Tyler M. Moore
Freddy Cliquet
Claire Leblond
Thomas Rolland
Anders Rosengren
Antonia San Jose Hannah Daisy Jessica Jessica Claire Bethany Eva Tony Declan Rosemary Jack Jessica Nicola Meng-Chuan Gwilym Amber Emily Hisham Julia Sara Ambrosino Sarai Yvonne Tabitha Miriam Alyssia Iris Maarten Anna Ver Loren Nico Sarah Larry Carsten Annika Daniel Ineke Yvette Maartje Elzbieta Elodie Kristiina Rouslan Guillaume Yang-Min Thomas Caceres
Antonia San Jose Hannah Daisy Jessica Jessica Claire Betha Caceres Hayward Crawley Faulkner Sabet Ellis Oakle
Antonia San José Cáceres
Hannah Hayward
Daisy Crawley
Jessica Faulkner
Jessica Sabet
Claire Ellis
Beth Oakley
Eva Loth
Tony Charman … (see 67 more)
Declan Murphy
Rosemary Holt
Jack Waldman
Jessica Upadhyay
Nicola Gunby
Meng-Chuan Lai
Gwilym Renouf
Amber N. V. Ruigrok
Emily Taylor
Hisham Ziauddeen
Julia Deakin
Sara Ambrosino di Bruttopilo
Sarai van Dijk
Yvonne Rijks
Tabitha Koops
Miriam Douma
Alyssia Spaan
Iris Selten
Maarten Steffers
Anna Ver Loren van Themaat
Nico Bast
Sarah Baumeister
Larry O’Dwyer
Carsten Bours
Annika Rausch
Daniel von Rhein
Ineke Cornelissen
Yvette de Bruin
Maartje Graauwmans
Elzbieta Kostrzewa
Elodie Cauvet
Kristiina Tammimies
Rouslan Sitnikow
Guillaume Dumas
Yang-Min Kim
Thomas Bourgeron
David M. Jonas Thomas Preben Bo Ole Merete Hougaard
David M. Hougaard
Jonas Bybjerg-Grauholm
Thomas Werge
Preben Bo Mortensen
Ole Mors
Merete Nordentoft
Dwaipayan Armandina Carrie Isabelle Tracey Paula Alex Graham J. Alexander E. P. Lidia V. Tal Madeline A. Deepak P. Jonathan Adhya
Dwaipayan Armandina Carrie Isabelle Tracey Paula Alex Graham Adhya Alamanza Allison Garvey Parsons Smith Tsompa
Dwaipayan Adhya
Armandina Alamanza
Carrie Allison
Isabelle Garvey
Tracey Parsons
Paula Smith
Alex Tsompanidis
Graham J. Burton
Alexander E. P. Heazell
Lidia V. Gabis
Tal Biron-Shental
Madeline A. Lancaster
Deepak P. Srivastava
Jonathan Mill
David H. Rowitch
Matthew E. Hurles
Daniel H. Geschwind
Anders D. Børglum
Elise B. Robinson
Jakob Grove
Hilary C. Martin
Simon Baron-Cohen
2022-06-01
Nature Genetics (published)
doi.org
Monocular Robot Navigation with Self-Supervised Pretrained Vision Transformers
Miguel Saavedra-Ruiz
Sacha Morin
Liam Paull
In this work, we consider the problem of learning a perception model for monocular robot navigation using few annotated images. Using a Visi… (see more)on Transformer (ViT) pretrained with a label-free self-supervised method, we successfully train a coarse image segmentation model for the Duckietown environment using 70 training images. Our model performs coarse image segmentation at the 8x8 patch level, and the inference resolution can be adjusted to balance prediction granularity and real-time perception constraints. We study how best to adapt a ViT to our task and environment, and find that some lightweight architectures can yield good single-image segmentation at a usable frame rate, even on CPU. The resulting perception model is used as the backbone for a simple yet robust visual servoing agent, which we deploy on a differential drive mobile robot to perform two tasks: lane following and obstacle avoidance.
2022-06-01
2022 19th Conference on Robots and Vision (CRV) (published)
doi.org
arxiv.org
Ageism and Artificial Intelligence: Protocol for a Scoping Review
Charlene H Chu
Kathleen Leslie
Jiamin Shi
Rune Nyrup
Andria Bianchi
Shehroz S Khan
S. A. Rahimi
Alexandra Lyn
Amanda Grenier
Background Artificial intelligence (AI) has emerged as a major driver of technological development in the 21st century, yet little attention… (see more) has been paid to algorithmic biases toward older adults. Objective This paper documents the search strategy and process for a scoping review exploring how age-related bias is encoded or amplified in AI systems as well as the corresponding legal and ethical implications. Methods The scoping review follows a 6-stage methodology framework developed by Arksey and O’Malley. The search strategy has been established in 6 databases. We will investigate the legal implications of ageism in AI by searching grey literature databases, targeted websites, and popular search engines and using an iterative search strategy. Studies meet the inclusion criteria if they are in English, peer-reviewed, available electronically in full text, and meet one of the following two additional criteria: (1) include “bias” related to AI in any application (eg, facial recognition) and (2) discuss bias related to the concept of old age or ageism. At least two reviewers will independently conduct the title, abstract, and full-text screening. Search results will be reported using the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) reporting guideline. We will chart data on a structured form and conduct a thematic analysis to highlight the societal, legal, and ethical implications reported in the literature. Results The database searches resulted in 7595 records when the searches were piloted in November 2021. The scoping review will be completed by December 2022. Conclusions The findings will provide interdisciplinary insights into the extent of age-related bias in AI systems. The results will contribute foundational knowledge that can encourage multisectoral cooperation to ensure that AI is developed and deployed in a manner consistent with ethical values and human rights legislation as it relates to an older and aging population. We will publish the review findings in peer-reviewed journals and disseminate the key results with stakeholders via workshops and webinars. Trial Registration OSF Registries AMG5P; https://osf.io/amg5p International Registered Report Identifier (IRRID) DERR1-10.2196/33211
2022-05-31
JMIR Research Protocols (published)
doi.org
Aligning artificial intelligence with climate change mitigation
Lynn H. Kaack
Priya L. Donti
Emma Strubell
George Kamiya
Felix Creutzig
David Rolnick
2022-05-31
Nature Climate Change (unknown)
doi.org
Conjugate Adder Net (CAddNet) - a Space-Efficient Approximate CNN
Lulan Shen
Maryam Ziaeefard
Brett Meyer
Warren Gross
James J. Clark
The AdderNet was recently developed as a way to implement deep neural networks without needing multiplication operations to combine weights … (see more)and inputs. Instead, absolute values of the difference between weights and inputs are used, greatly reducing the gate-level implementation complexity. Training of AdderNets is challenging, however, and the loss curves during training tend to fluctuate significantly. In this paper we propose the Conjugate Adder Network, or CAddNet, which uses the difference between the absolute values of conjugate pairs of inputs and the weights. We show that this can be implemented simply via a single minimum operation, resulting in a roughly 50% reduction in logic gate complexity as compared with AdderNets. The CAddNet method also stabilizes training as compared with AdderNets, yielding training curves similar to standard CNNs.
2022-05-31
2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW) (published)
doi.org
Gradient-based learning drives robust representations in recurrent neural networks by balancing compression and expansion.
Matthew Farrell
Matthew Farrell
Stefano Recanatesi
Timothy Moore
Guillaume Lajoie
Eric Shea-Brown
Neural networks need the right representations of input data to learn. Here we ask how gradient-based learning shapes a fundamental property… (see more) of representations in recurrent neural networks (RNNs)—their dimensionality. Through simulations and mathematical analysis, we show how gradient descent can lead RNNs to compress the dimensionality of their representations in a way that matches task demands during training while supporting generalization to unseen examples. This can require an expansion of dimensionality in early timesteps and compression in later ones, and strongly chaotic RNNs appear particularly adept at learning this balance. Beyond helping to elucidate the power of appropriately initialized artificial RNNs, this fact has implications for neurobiology as well. Neural circuits in the brain reveal both high variability associated with chaos and low-dimensional dynamical structures. Taken together, our findings show how simple gradient-based learning rules lead neural networks to solve tasks with robust representations that generalize to new cases. Neural networks in the brain often exhibit chaotic dynamics that can be captured by a small number of dimensions. Farrell et al. find that recurrent neural networks trained with gradient-based learning rules exhibit similar features. This helps form robust but generalizable input representations.
2022-05-31
Nature Machine Intelligence (published)
doi.org