Publications

Over the past years, foundation models have caused a paradigm shift in machine learning due to their unprecedented capabilities for zero-sho… (see more)t and few-shot generalization. However, despite the success of foundation models in modalities such as natural language processing and computer vision, the development of foundation models for time series forecasting has lagged behind. We present Lag-Llama, a general-purpose foundation model for univariate probabilistic time series forecasting based on a decoder-only transformer architecture that uses lags as covariates. Lag-Llama is pretrained on a large corpus of diverse time series data from several domains, and demonstrates strong zero-shot generalization capabilities compared to a wide range of forecasting models on downstream datasets across domains. Moreover, when fine-tuned on relatively small fractions of such previously unseen datasets, Lag-Llama achieves state-of-the-art performance, outperforming prior deep learning approaches, emerging as the best general-purpose model on average. Lag-Llama serves as a strong contender to the current state-of-art in time series forecasting and paves the way for future advancements in foundation models tailored to time series data.

2023-10-12

ArXiv (preprint)

arxiv.org

Lag-Llama: Towards Foundation Models for Probabilistic Time Series Forecasting

Kashif Rasul

Arjun Ashok

Andrew Robert Williams

Arian Khorasani

George Adamopoulos

Rishika Bhagwatkar

Marin Bilovs

Hena Ghonia

Nadhir Hassen

Anderson Schneider

Sahil Garg

Alexandre Drouin

Nicolas Chapados

Yuriy Nevmyvaka

Irina Rish

2023-10-12

ArXiv (preprint)

arxiv.org

PhyloGFN: Phylogenetic inference with generative flow networks

Ming Yang Zhou

Zichao Yan

Elliot Layne

Moksh J. Jain

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history a… (see more)nd numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains challenging: the high complexity of tree space poses a significant obstacle for the current combinatorial and probabilistic techniques. In this paper, we adopt the framework of generative flow networks (GFlowNets) to tackle two core problems in phylogenetics: parsimony-based and Bayesian phylogenetic inference. Because GFlowNets are well-suited for sampling complex combinatorial structures, they are a natural choice for exploring and sampling from the multimodal posterior distribution over tree topologies and evolutionary distances. We demonstrate that our amortized posterior sampler, PhyloGFN, produces diverse and high-quality evolutionary hypotheses on real benchmark datasets. PhyloGFN is competitive with prior works in marginal likelihood estimation and achieves a closer fit to the target distribution than state-of-the-art variational inference methods. Our code is available at https://github.com/zmy1116/phylogfn.

2023-10-12

ArXiv (preprint)

doi.org

arxiv.org

AAPM Medical Physics Practice Guideline 14.a: Yttrium‐90 microsphere radioembolization

Nathan C. Busse

Muthana S. A. L. Al‐Ghazi

Nadine Abi‐Jaoudeh

Diane Alvarez

Ahmet S. Ayan

Erli Chen

Michael D. Chuong