Publications

Curating the Twitter Election Integrity Datasets for Better Online Troll Characterization
Albert M. Orozco Camacho
In modern days, social media platforms provide accessible channels for the inter-1 action and immediate reflection of the most important ev… (see more)ents happening around 2 the world. In this paper, we, firstly, present a curated set of datasets whose origin 3 stem from the Twitter’s Information Operations 1 efforts. More notably, these 4 accounts, which have been already suspended, provide a notion of how state-backed 5 human trolls operate. 6 Secondly, we present detailed analyses of how these behaviours vary over time, 7 and motivate its use and abstraction in the context of deep representation learning: 8 for instance, to learn and, potentially track, troll behaviour. We present baselines 9 for such tasks and highlight the differences there may exist within the literature. 10 Finally, we utilize the representations learned for behaviour prediction to classify 11 trolls from "real" users, using a sample of non-suspended active accounts. 12
Flexible Option Learning
Temporal abstraction in reinforcement learning (RL), offers the promise of improving generalization and knowledge transfer in complex enviro… (see more)nments, by propagating information more efficiently over time. Although option learning was initially formulated in a way that allows updating many options simultaneously, using off-policy, intra-option learning (Sutton, Precup & Singh, 1999), many of the recent hierarchical reinforcement learning approaches only update a single option at a time: the option currently executing. We revisit and extend intra-option learning in the context of deep reinforcement learning, in order to enable updating all options consistent with current primitive action choices, without introducing any additional estimates. Our method can therefore be naturally adopted in most hierarchical RL frameworks. When we combine our approach with the option-critic algorithm for option discovery, we obtain significant improvements in performance and data-efficiency across a wide variety of domains.
Patient health records and whole viral genomes from an early SARS-CoV-2 outbreak in a Quebec hospital reveal features associated with favorable outcomes
Bastien Paré
Marieke Rozendaal
Raphaël Poujol
Shawn M. Simpson
Jean-Christophe Grenier
Henry Xing
Miguelle Sanchez
Ariane Yechouron
Ronald Racette
Julie G. Hussin
Ivan Pavlov
Martin A. Smith
The first confirmed case of COVID-19 in Quebec, Canada, occurred at Verdun Hospital on February 25, 2020. A month later, a localized outbrea… (see more)k was observed at this hospital. We performed tiled amplicon whole genome nanopore sequencing on nasopharyngeal swabs from all SARS-CoV-2 positive samples from 31 March to 17 April 2020 in 2 local hospitals to assess the viral diversity of the outbreak. We report 264 viral genomes from 242 individuals (both staff and patients) with associated clinical features and outcomes, as well as longitudinal samples, technical replicates and the first publicly disseminated SARS-CoV-2 genomes in Quebec. Viral lineage assessment identified multiple subclades in both hospitals, with a predominant subclade in the Verdun outbreak, indicative of hospital-acquired transmission. Dimensionality reduction identified two subclades that evaded supervised lineage assignment methods, including Pangolin, and identified certain symptoms (headache, myalgia and sore throat) that are significantly associated with favorable patient outcomes. We also address certain limitations of standard SARS-CoV-2 bioinformatics procedures, notably when presented with multiple viral haplotypes.
Adapting to the COVID‐19 pandemic in cohort studies: Validation of online assessments of cognition and neuropsychiatric symptoms in an aging population
Firoza Z Lussier
Stijn Servaes
Min Su Kang
Gleb Bezgin
Mira Chamoun
Jenna Stevenson
Nesrine Rahmouni
Alyssa Stevenson
Tharick A. Pascoal
Suzanne King
Serge Gauthier
Pedro Rosa‐Neto
The occurrence of the COVID‐19 pandemic has had a significant impact on cohort studies, particularly those whose subjects are at higher ri… (see more)sk of developing complications from the virus. As such, assessment methods must be adapted to minimize COVID‐19 exposure risk. The TRIAD (Translational Biomarkers of Aging and Dementia) cohort assessed N=292 individuals during initial COVID‐19 lockdown measures by telephone interview to rate cognition, neuropsychiatric symptoms, and impact of the pandemic. To increase speed and efficiency of data collection, we aim to follow these individuals by means of online survey. Here, we present a validation of our online assessment tools by comparing data obtained through both methods (phone interview and online survey) in the same subjects.
Cognitive health mediates the effect of hippocampal volume on COVID‐19‒related knowledge or anxiety change during the COVID‐19 pandemic
Min Su Kang
Julie Ottoy
Stijn Servaes
Firoza Z Lussier
Gleb Bezgin
Mira Chamoun
Jenna Stevenson
Suzanne King
Serge Gauthier
Pedro Rosa‐Neto
Our finding highlights the poorer knowledge of COVID19 and related risks in individuals with cognitive/memory impairments; the CDRSOB, indic… (see more)ative of cognitive health, significantly mediated the effect of hippocampal volume on the rate of change in anxiety or knowledge on COVID19 in our cohort. This study urges for a more effective strategy and policy about informing and educating the individual with cognitive/memory impairment on COVID19 and related risks.
Learning Assisted Identification of Scenarios Where Network Optimization Algorithms Under-Perform
Dmitriy Rivkin
X. T. Chen
Xue Liu
We present a generative adversarial method that uses deep learning to identify network load traffic conditions in which network optimization… (see more) algorithms under-perform other known algorithms: the Deep Convolutional Failure Generator (DCFG). The spatial distribution of network load presents challenges for network operators for tasks such as load balancing, in which a network optimizer attempts to maintain high quality communication while at the same time abiding capacity constraints. Testing a network optimizer for all possible load distributions is challenging if not impossible. We propose a novel method that searches for load situations where a target network optimization method underperforms baseline, which are key test cases that can be used for future refinement and performance optimization. By modeling a realistic network simulator's quality assessments with a deep network and, in parallel, optimizing a load generation network, our method efficiently searches the high dimensional space of load patterns and reliably finds cases in which a target network optimization method under-performs a baseline by a significant margin.
Online Partisan Polarization of COVID-19
Sacha Lévy
Gabrielle Desrosiers-Brisebois
Andre Blais
In today’s age of (mis)information, many people utilize various social media platforms in an attempt to shape public opinion on sever… (see more)al important issues, including elections and the COVID-19 pandemic. These two topics have recently become intertwined given the importance of complying with public health measures related to COVID-19 and politicians’ management of the pandemic. Motivated by this, we study the partisan polarization of COVID-19 discussions on social media. We propose and utilize a novel measure of partisan polarization to analyze more than 380 million posts from Twitter and Parler around the 2020 US presidential election. We find strong correlation between peaks in polarization and polarizing events, such as the January 6th Capitol Hill riot. We further classify each post into key COVID-19 issues of lockdown, masks, vaccines, as well as miscellaneous, to investigate both the volume and polarization on these topics and how they vary through time. Parler includes more negative discussions around lockdown and masks, as expected, but not much around vaccines. We also observe more balanced discussions on Twitter and a general disconnect between the discussions on Parler and Twitter.
Tau‐load in the lingual gyrus impacts anxiety levels during the COVID‐19 pandemic in participants of longitudinal observational studies in aging
Stijn Servaes
Firoza Z Lussier
Gleb Bezgin
Yi‐Ting Wang
Jenna Stevenson
Cécile Tissot
Guillaume Elgbeili
Jaime Fernandez Arias
Joseph Therriault
Andréa Lessa Benedet
Mira Chamoun
Tharick A. Pascoal
Suzanne King
Serge Gauthier
Pedro Rosa‐Neto
By obtaining a better grasp on the impact of the COVID‐19 pandemic on individuals with cognitive impairment, this knowledge could be used … (see more)to improve the delivery of information to this particular group. We aimed to assess the relationship between tau deposition and the change in anxiety levels, before and during the pandemic. We hypothesized that since the pandemic, higher tau loads would lower the change in anxiety. Furthermore, we expected these anxiety levels not to be associated with COVID‐19 related stress in participants with cognitive decline. 63 participants of the Translational Biomarker of Aging and Dementia (TRIAD) cohort (cognitively healthy, N=38; cognitively impaired, N=25, of which 7 had dementia due to Alzheimer’s disease), were assessed to evaluate their individual change in anxiety levels (GAD‐7). This was done at three different timepoints, of which the latest fell during the COVID‐19 lockdown period. Two rates of change, one before and one during the pandemic, were determined using the following definition: (next timepoint – current timepoint)/time difference. In addition, at the latest timepoint, subjective stress due to COVID‐19 was measured using the Montreal Assessment of Stress related to COVID‐19 (MASC). To assess the levels of tau, standard uptake value ratios (SUVR) from previously obtained [18F]MK‐6240 PET‐scans were used. [18F]MK‐6240 tracer binding in the lingual gyrus was negatively associated with the rate of change in GAD‐7 scores after correcting for age, sex, years of education and the presence of APOE ε4, but only in cognitively impaired individuals during the pandemic (fig 1A). In addition, the GAD‐7 score at the latest timepoint was associated with stress related to COVID‐19, but only in cognitively healthy individuals (fig 1B and 1C). The presence of tau in the lingual gyrus negatively affected the rate of change in GAD‐7 scores during the COVID‐19 pandemic in individuals with cognitive impairment. This could indicate that information pertaining to the pandemic does not reach these individuals in an efficient manner. The missing association between COVID‐19 induced stress and the latest GAD‐7 scores in these individuals is a further indication of this.
Tau‐PET is associated with knowledge of COVID‐19, COVID‐19‐related distress, and change in sleep quality during the pandemic
Firoza Z Lussier
Stijn Servaes
Min Su Kang
Gleb Bezgin
Mira Chamoun
Jenna Stevenson
Nesrine Rahmouni
Alyssa Stevenson
Tharick A. Pascoal
Suzanne King
Guillaume Elgbeili
Serge Gauthier
Pedro Rosa‐Neto
While the global COVID‐19 pandemic has hindered many human research operations, it has allowed for the investigation of novel scientific q… (see more)uestions. Particularly, the effects of the pandemic and its resulting social isolation on elderly individuals and their association with Alzheimer’s disease biomarkers remains a broad and open question. Here, we sought to investigate whether knowledge of COVID‐19, pandemic‐related distress, and changes in sleep quality were associated with in vivo tau deposition in an AD‐enriched cohort.
Hypo- and hyper- sensory processing heterogeneity in Autism Spectrum Disorder
Aline Lefebvre
Julian Tillmann
Freddy Cliquet
Frederique Amsellem
Anna Maruani
Claire Leblond
Anita Beggiato
David Germanaud
Anouck Amestoy
Myriam Ly‐Le Moal
Daniel Umbricht
Christopher Chattam
Lorraine Murtagh
Manuel Bouvard
Marion Leboyer
Tony Charman
Thomas Bourgeron
Richard Delorme
Background. Sensory processing atypicalities are part of the core symptoms of autism spectrum disorder (ASD) and could result from an excita… (see more)tion/inhibition imbalance. Yet, the convergence level of phenotypic sensory processing atypicalities with genetic alterations in GABA-ergic and glutamatergic pathways remains poorly understood. This study aimed to characterize the distribution of hypo/hyper-sensory profile among individuals with ASD and investigate the role of deleterious mutations in GABAergic and glutamatergic pathways related genes in sensory processing atypicalities. Method. From the Short Sensory Profile (SSP) questionnaire, we defined and explored a score – the differential Short Sensory Profile (dSSP) - as a normalized and centralized hypo/hypersensitivity ratio for 1136 participants (533 with ASD, 210 first-degree relatives, and 267 controls) from two independent study samples (PARIS and LEAP). We also performed an unsupervised item-based clustering analysis on SSP items scores to validate this new categorization in terms of hypo and hyper sensitivity. We then explored the link between the dSSP score and the burden of deleterious mutations in a subset of individuals for which whole-genome sequencing data were available. Results. We observed a mean dSSP score difference between ASD and controls, driven mostly by a high dSSP score variability among groups (PARIS: p0.0001, η2 = 0.0001, LEAP: p0.0001, Cohen’s d=3.67). First-degree relatives were with an intermediate distribution variability prof
Fixing Bias in Reconstruction-Based Anomaly Detection with Lipschitz Discriminators
Anomaly detection is of great interest in fields where abnormalities need to be identified and corrected (e.g., medicine and finance). Deep … (see more)learning methods for this task often rely on autoencoder reconstruction error, sometimes in conjunction with other errors. We show that this approach exhibits intrinsic biases that lead to undesirable results. Reconstruction-based methods are sensitive to training-data outliers and simple-to-reconstruct points. Instead, we introduce a new unsupervised Lipschitz anomaly discriminator that does not suffer from these biases. Our anomaly discriminator is trained, similar to the ones used in GANs, to detect the difference between the training data and corruptions of the training data. We show that this procedure successfully detects unseen anomalies with guarantees on those that have a certain Wasserstein distance from the data or corrupted training set. These additions allow us to show improved performance on MNIST, CIFAR10, and health record data.
Processing visual ambiguity in fractal patterns: Pareidolia as a sign of creativity
Antoine Bellemare-Pepin
Yann Harel
Jordan O'Byrne
Geneviève Mageau
Arne Dietrich

Creativity is a highly sought after and multifaceted skill. Unfortunately, we only have a loose grasp on its cognitive underpinnings. Emp… (see more)irical research typically probes creativity by estimating the potential for problem solving and novel idea generation, a process known as “divergent thinking”. Here, by contrast, we examine creativity through the lens of perceptual abilities. In particular, we ask whether creative individuals are better at perceiving recognizable forms in noisy or ambiguous stimuli, a phenomenon known as pareidolia. To this end, we designed a visual perception task in which 50 participants, with various levels of creativity, were presented with ambiguous stimuli and asked to identify as many recognizable forms as possible. The stimuli consisted of cloud-like images with various levels of complexity, which we controlled by manipulating fractal dimension (FD) and contrast level. We found that pareidolic perceptions arise more often and more rapidly in individuals that are more creative. Furthermore, the emergence of pareidolia in individuals with lower creativity scores was more restricted to images with a narrow range of FD values, suggesting a wider repertoire for perceptual abilities in creative individuals. Our findings suggest that pareidolia may be used as a perceptual proxy of idea generation abilities, a key component of creative behavior. In sum, we extend the established body of work on divergent thinking, by introducing divergent perception as a complementary manifestation of the creative mind. These findings expand our understanding of the perception-creation link and open new paths in studying creative behavior in humans.