Learn how to leverage generative AI to support and improve your productivity at work. The next cohort will take place online on April 28 and 30, 2026, in French.
We use cookies to analyze the browsing and usage of our website and to personalize your experience. You can disable these technologies at any time, but this may limit certain functionalities of the site. Read our Privacy Policy for more information.
Setting cookies
You can enable and disable the types of cookies you wish to accept. However certain choices you make could affect the services offered on our sites (e.g. suggestions, personalised ads, etc.).
Essential cookies
These cookies are necessary for the operation of the site and cannot be deactivated. (Still active)
Analytics cookies
Do you accept the use of cookies to measure the audience of our sites?
Multimedia Player
Do you accept the use of cookies to display and allow you to watch the video content hosted by our partners (YouTube, etc.)?
Publications
General Causal Imputation via Synthetic Interventions
Given two sets of elements (such as cell types and drug compounds), researchers typically only have access to a limited subset of their inte… (see more)ractions. The task of causal imputation involves using this subset to predict unobserved interactions. Squires et al. (2022) have proposed two estimators for this task based on the synthetic interventions (SI) estimator: SI-A (for actions) and SI-C (for contexts). We extend their work and introduce a novel causal imputation estimator, generalized synthetic interventions (GSI). We prove the identifiability of this estimator for data generated from a more complex latent factor model. On synthetic and real data we show empirically that it recovers or outperforms their estimators.
With growing application of machine learning (ML) technologies in healthcare, there have been calls for developing techniques to understand … (see more)and mitigate biases these systems may exhibit. Fair-ness considerations in the development of ML-based solutions for health have particular implications for Africa, which already faces inequitable power imbalances between the Global North and South.This paper seeks to explore fairness for global health, with Africa as a case study. We conduct a scoping review to propose axes of disparities for fairness consideration in the African context and delineate where they may come into play in different ML-enabled medical modalities. We then conduct qualitative research studies with 672 general population study participants and 28 experts inML, health, and policy focused on Africa to obtain corroborative evidence on the proposed axes of disparities. Our analysis focuses on colonialism as the attribute of interest and examines the interplay between artificial intelligence (AI), health, and colonialism. Among the pre-identified attributes, we found that colonial history, country of origin, and national income level were specific axes of disparities that participants believed would cause an AI system to be biased.However, there was also divergence of opinion between experts and general population participants. Whereas experts generally expressed a shared view about the relevance of colonial history for the development and implementation of AI technologies in Africa, the majority of the general population participants surveyed did not think there was a direct link between AI and colonialism. Based on these findings, we provide practical recommendations for developing fairness-aware ML solutions for health in Africa.
2024-10-28
Proceedings of the 4th ACM Conference on Equity and Access in Algorithms, Mechanisms, and Optimization (published)
As robots become more common for both able-bodied individuals and those living with a disability, it is increasingly important that lay peop… (see more)le be able to drive multi-degree-of-freedom platforms with low-dimensional controllers. One approach is to use state-conditioned action mapping methods to learn mappings between low-dimensional controllers and high DOF manipulators -- prior research suggests these mappings can simplify the teleoperation experience for users. Recent works suggest that neural networks predicting a local linear function are superior to the typical end-to-end multi-layer perceptrons because they allow users to more easily undo actions, providing more control over the system. However, local linear models assume actions exist on a linear subspace and may not capture nuanced actions in training data. We observe that the benefit of these mappings is being an odd function concerning user actions, and propose end-to-end nonlinear action maps which achieve this property. Unfortunately, our experiments show that such modifications offer minimal advantages over previous solutions. We find that nonlinear odd functions behave linearly for most of the control space, suggesting architecture structure improvements are not the primary factor in data-driven teleoperation. Our results suggest other avenues, such as data augmentation techniques and analysis of human behavior, are necessary for action maps to become practical in real-world applications, such as in assistive robotics to improve the quality of life of people living with w disability.
Computational neuroscience relies on gradient descent (GD) for training artificial neural network (ANN) models of the brain. The advantage o… (see more)f GD is that it is effective at learning difficult tasks. However, it produces ANNs that are a poor phenomenological fit to biology, making them less relevant as models of the brain. Specifically, it violates Dale’s law, by allowing synapses to change from excitatory to inhibitory, and leads to synaptic weights that are not log-normally distributed, contradicting experimental data. Here, starting from first principles of optimisation theory, we present an alternative learning algorithm, exponentiated gradient (EG), that respects Dale’s Law and produces log-normal weights, without losing the power of learning with gradients. We also show that in biologically relevant settings EG outperforms GD, including learning from sparsely relevant signals and dealing with synaptic pruning. Altogether, our results show that EG is a superior learning algorithm for modelling the brain with ANNs.
In drug discovery, highly automated high-throughput laboratories are used to screen a large number of compounds in search of effective drugs… (see more). These experiments are expensive, so one might hope to reduce their cost by only experimenting on a subset of the compounds, and predicting the outcomes of the remaining experiments. In this work, we model this scenario as a sequential subset selection problem: we aim to select the smallest set of candidates in order to achieve some desired level of accuracy for the system as a whole. Our key observation is that, if there is heterogeneity in the difficulty of the prediction problem across the input space, selectively obtaining the labels for the hardest examples in the acquisition pool will leave only the relatively easy examples to remain in the inference set, leading to better overall system performance. We call this mechanism inference set design, and propose the use of a confidence-based active learning solution to prune out these challenging examples. Our algorithm includes an explicit stopping criterion that interrupts the acquisition loop when it is sufficiently confident that the system has reached the target performance. Our empirical studies on image and molecular datasets, as well as a real-world large-scale biological assay, show that active learning for inference set design leads to significant reduction in experimental cost while retaining high system performance.