Portrait of Adrien Aumon is unavailable

Adrien Aumon

PhD - Université de Montréal
Supervisor
Research Topics
Dimensionality Reduction Methods
Exploratory Data Analysis
Manifold Learning
Medical Machine Learning

Publications

Random Forest Autoencoders for Guided Representation Learning
Kevin R. Moon
Jake S. Rhodes
Decades of research have produced robust methods for unsupervised data visualization, yet supervised visualization…
Random Forest Autoencoders for Guided Representation Learning
Kevin R. Moon
Jake S. Rhodes
Decades of research have produced robust methods for unsupervised data visualization, yet supervised visualization…
Gaining Biological Insights through Supervised Data Visualization
Jake S. Rhodes
Marc Girard
Catherine Larochelle
Boaz Lahav
Elsa Brunet-Ratnasingham
Amélie Pagliuzza
Lorie Marchitto
Wei Zhang
Adele Cutler
F. Grand'Maison
Anhong Zhou
Andrés Finzi
Nicolas Chomont
Daniel E. Kaufmann
Alexandre Prat
Kevin R. Moon
Dimensionality reduction-based data visualization is pivotal in comprehending complex biological data. The most common methods, such as PHAT… (see more)E, t-SNE, and UMAP, are unsupervised and therefore reflect the dominant structure in the data, which may be independent of expert-provided labels. Here we introduce a supervised data visualization method called RF-PHATE, which integrates expert knowledge for further exploration of the data. RF-PHATE leverages random forests to capture intricate featurelabel relationships. Extracting information from the forest, RF-PHATE generates low-dimensional visualizations that highlight relevant data relationships while disregarding extraneous features. This approach scales to large datasets and applies to classification and regression. We illustrate RF-PHATE’s prowess through three case studies. In a multiple sclerosis study using longitudinal clinical and imaging data, RF-PHATE unveils a sub-group of patients with non-benign relapsingremitting Multiple Sclerosis, demonstrating its aptitude for time-series data. In the context of Raman spectral data, RF-PHATE effectively showcases the impact of antioxidants on diesel exhaust-exposed lung cells, highlighting its proficiency in noisy environments. Furthermore, RF-PHATE aligns established geometric structures with COVID-19 patient outcomes, enriching interpretability in a hierarchical manner. RF-PHATE bridges expert insights and visualizations, promising knowledge generation. Its adaptability, scalability, and noise tolerance underscore its potential for widespread adoption.
Gaining Biological Insights through Supervised Data Visualization
Jake S. Rhodes
Marc Girard
Catherine Larochelle
Elsa Brunet-Ratnasingham
Amélie Pagliuzza
Lorie Marchitto
Wei Zhang
Adele Cutler
F. Grand'Maison
Anhong Zhou
Andrés Finzi
Nicolas Chomont
Daniel E. Kaufmann
Alexandre Prat
Kevin R. Moon
Dimensionality reduction-based data visualization is pivotal in comprehending complex biological data. The most common methods, such as PHAT… (see more)E, t-SNE, and UMAP, are unsupervised and therefore reflect the dominant structure in the data, which may be independent of expert-provided labels. Here we introduce a supervised data visualization method called RF-PHATE, which integrates expert knowledge for further exploration of the data. RF-PHATE leverages random forests to capture intricate featurelabel relationships. Extracting information from the forest, RF-PHATE generates low-dimensional visualizations that highlight relevant data relationships while disregarding extraneous features. This approach scales to large datasets and applies to classification and regression. We illustrate RF-PHATE’s prowess through three case studies. In a multiple sclerosis study using longitudinal clinical and imaging data, RF-PHATE unveils a sub-group of patients with non-benign relapsingremitting Multiple Sclerosis, demonstrating its aptitude for time-series data. In the context of Raman spectral data, RF-PHATE effectively showcases the impact of antioxidants on diesel exhaust-exposed lung cells, highlighting its proficiency in noisy environments. Furthermore, RF-PHATE aligns established geometric structures with COVID-19 patient outcomes, enriching interpretability in a hierarchical manner. RF-PHATE bridges expert insights and visualizations, promising knowledge generation. Its adaptability, scalability, and noise tolerance underscore its potential for widespread adoption.
Enhancing Supervised Visualization through Autoencoder and Random Forest Proximities for Out-of-Sample Extension
Kevin R. Moon
Jake S. Rhodes
The value of supervised dimensionality reduction lies in its ability to uncover meaningful connections between data features and labels. Com… (see more)mon dimensionality reduction methods embed a set of fixed, latent points, but are not capable of generalizing to an unseen test set. In this paper, we provide an out-of-sample extension method for the random forest-based supervised dimensionality reduction method, RF-PHATE, combining information learned from the random forest model with the function-learning capabilities of autoencoders. Through quantitative assessment of various autoencoder architectures, we identify that networks that reconstruct random forest proximities are more robust for the embedding extension problem. Furthermore, by leveraging proximity-based prototypes, we achieve a 40% reduction in training time without compromising extension quality. Our method does not require label information for out-of-sample points, thus serving as a semi-supervised method, and can achieve consistent quality using only 10% of the training data.